Direct evidence for GABAergic activity of Withania somnifera on mammalian ionotropic GABAA and GABAρ receptors M Candelario, E Cuellar, JM Reyes-Ruiz, N Darabedian, Z Feimeng, ... Journal of ethnopharmacology 171, 264-272, 2015 | 102 | 2015 |
Lactate regulates cell cycle by remodelling the anaphase promoting complex W Liu, Y Wang, LHM Bozi, PD Fischer, MP Jedrychowski, H Xiao, T Wu, ... Nature 616 (7958), 790-797, 2023 | 85 | 2023 |
The new chemical reporter 6-alkynyl-6-deoxy-GlcNAc reveals O-GlcNAc modification of the apoptotic caspases that can block the cleavage/activation of caspase-8 KN Chuh, AR Batt, BW Zaro, N Darabedian, NP Marotta, CK Brennan, ... Journal of the American Chemical Society 139 (23), 7872-7885, 2017 | 62 | 2017 |
The Metabolic Chemical Reporter 6-Azido-6-deoxy-glucose Further Reveals the Substrate Promiscuity of O-GlcNAc Transferase and Catalyzes the Discovery of Intracellular … N Darabedian, J Gao, KN Chuh, CM Woo, MR Pratt Journal of the American Chemical Society 140 (23), 7092-7100, 2018 | 58 | 2018 |
Optimization of chemoenzymatic mass tagging by strain-promoted cycloaddition (SPAAC) for the determination of O-GlcNAc stoichiometry by western blotting N Darabedian, JW Thompson, KN Chuh, LC Hsieh-Wilson, MR Pratt Biochemistry 57 (40), 5769-5774, 2018 | 55 | 2018 |
MYPT1 O-GlcNAc modification regulates sphingosine-1-phosphate mediated contraction NJ Pedowitz, AR Batt, N Darabedian, MR Pratt Nature chemical biology 17 (2), 169-177, 2021 | 31 | 2021 |
Nitropyrene photoprobes: making them, and what are they good for? EM Espinoza, B Xia, N Darabedian, JM Larsen, V Nuñez, D Bao, JT Mac, ... European Journal of Organic Chemistry 2016 (2), 343-356, 2016 | 26 | 2016 |
Depletion of creatine phosphagen energetics with a covalent creatine kinase inhibitor N Darabedian, W Ji, M Fan, S Lin, HS Seo, EV Vinogradova, TM Yaron, ... Nature chemical biology 19 (7), 815-824, 2023 | 25 | 2023 |
pH-Dependent Coordination of Pb2+ to Metallothionein2: Structures and Insight into Lead Detoxification Y He, M Liu, N Darabedian, Y Liang, D Wu, J Xiang, F Zhou Inorganic Chemistry 53 (6), 2822-2830, 2014 | 25 | 2014 |
O-acetylated chemical reporters of glycosylation can display metabolism-dependent background labeling of proteins but are generally reliable tools for the identification of … N Darabedian, B Yang, R Ding, G Cutolo, BW Zaro, CM Woo, MR Pratt Frontiers in Chemistry 8, 318, 2020 | 24 | 2020 |
Bioorthogonal profiling of a cancer cell proteome identifies a large set of 3-bromopyruvate targets beyond glycolysis N Darabedian, TC Chen, H Molina, MR Pratt, AH Schönthal ACS chemical biology 13 (11), 3054-3058, 2018 | 24 | 2018 |
An improved Bathocuproine assay for accurate valence identification and quantification of copper bound by biomolecules D Chen, N Darabedian, Z Li, T Kai, D Jiang, F Zhou Analytical biochemistry 497, 27-35, 2016 | 22 | 2016 |
Ca2+ Interacts with Glu-22 of Aβ(1–42) and Phospholipid Bilayers to Accelerate the Aβ(1–42) Aggregation Below the Critical Micelle Concentration X Yi, Y Zhang, M Gong, X Yu, N Darabedian, J Zheng, F Zhou Biochemistry 54 (41), 6323-6332, 2015 | 21 | 2015 |
Identifying potentially O-GlcNAcylated proteins using metabolic labeling, bioorthogonal enrichment, and Western blotting N Darabedian, MR Pratt Methods in enzymology 622, 293-307, 2019 | 15 | 2019 |
Exo-enzymatic addition of diazirine-modified sialic acid to cell surfaces enables photocrosslinking of glycoproteins N Yarravarapu, RSR Konada, N Darabedian, NJ Pedowitz, ... Bioconjugate chemistry 33 (5), 781-787, 2022 | 13 | 2022 |
Azide‐and Alkyne‐Bearing Metabolic Chemical Reporters of Glycosylation Show Structure‐Dependent Feedback Inhibition of the Hexosamine Biosynthetic Pathway LA Walter, AR Batt, N Darabedian, BW Zaro, MR Pratt ChemBioChem 19 (18), 1918-1921, 2018 | 12 | 2018 |
Bioinspired approach toward molecular electrets: synthetic proteome for materials EM Espinoza, JM Larsen-Clinton, M Krzeszewski, N Darabedian, ... Pure and Applied Chemistry 89 (12), 1777-1797, 2017 | 12 | 2017 |
Translation of microbiota short-chain fatty acid mechanisms affords anti-infective acyl-salicylic acid derivatives X Yang, ER Forster, N Darabedian, AT Kim, MR Pratt, A Shen, HC Hang ACS Chemical Biology 15 (5), 1141-1147, 2020 | 10 | 2020 |
Dyes and Redox Couples with Matched Energy Levels: Elimination of the Dye‐Regeneration Energy Loss in Dye‐Sensitized Solar Cells D Jiang, N Darabedian, S Ghazarian, Y Hao, M Zhgamadze, N Majaryan, ... ChemPhysChem 16 (16), 3385-3388, 2015 | 8 | 2015 |
Norepinephrine–Fe (III)–ATP Ternary Complex and Its Relevance to Parkinson’s Disease L Kou, Y Duan, P Wang, Y Fu, N Darabedian, Y He, D Jiang, D Chen, ... ACS Chemical Neuroscience 10 (6), 2777-2785, 2019 | 5 | 2019 |