Chemically defined generation of human cardiomyocytes PW Burridge, E Matsa, P Shukla, ZC Lin, JM Churko, AD Ebert, F Lan, ... Nature methods 11 (8), 855-860, 2014 | 1673 | 2014 |
Abnormal Calcium Handling Properties Underlie Familial Hypertrophic Cardiomyopathy Pathology in Patient-Specific Induced Pluripotent Stem Cells F Lan, AS Lee, P Liang, V Sanchez-Freire, PK Nguyen, L Wang, L Han, ... Cell Stem Cell 12 (1), 101-113, 2013 | 727 | 2013 |
Drug screening using a library of human induced pluripotent stem cell–derived cardiomyocytes reveals disease-specific patterns of cardiotoxicity P Liang, F Lan, AS Lee, T Gong, V Sanchez-Freire, Y Wang, S Diecke, ... Circulation 127 (16), 1677-1691, 2013 | 617 | 2013 |
Optimized CRISPR guide RNA design for two high-fidelity Cas9 variants by deep learning D Wang, C Zhang, B Wang, B Li, Q Wang, D Liu, H Wang, Y Zhou, L Shi, ... Nature communications 10 (1), 4284, 2019 | 587 | 2019 |
Screening drug-induced arrhythmia using human induced pluripotent stem cell–derived cardiomyocytes and low-impedance microelectrode arrays EG Navarrete, P Liang, F Lan, V Sanchez-Freire, C Simmons, T Gong, ... Circulation 128 (11_suppl_1), S3-S13, 2013 | 346 | 2013 |
Patient-specific and genome-edited induced pluripotent stem cell–derived cardiomyocytes elucidate single-cell phenotype of Brugada syndrome P Liang, K Sallam, H Wu, Y Li, I Itzhaki, P Garg, Y Zhang, V Termglichan, ... Journal of the American College of Cardiology 68 (19), 2086-2096, 2016 | 225 | 2016 |
Short-term immunosuppression promotes engraftment of embryonic and induced pluripotent stem cells JI Pearl, AS Lee, DB Leveson-Gower, N Sun, Z Ghosh, F Lan, J Ransohoff, ... Cell stem cell 8 (3), 309-317, 2011 | 220 | 2011 |
Epigenetic regulation of phosphodiesterases 2A and 3A underlies compromised β-adrenergic signaling in an iPSC model of dilated cardiomyopathy H Wu, J Lee, LG Vincent, Q Wang, M Gu, F Lan, JM Churko, KI Sallam, ... Cell stem cell 17 (1), 89-100, 2015 | 195 | 2015 |
Genome editing of isogenic human induced pluripotent stem cells recapitulates long QT phenotype for drug testing Y Wang, P Liang, F Lan, H Wu, L Lisowski, M Gu, S Hu, MA Kay, ... Journal of the American College of Cardiology 64 (5), 451-459, 2014 | 181 | 2014 |
Novel microRNA prosurvival cocktail for improving engraftment and function of cardiac progenitor cell transplantation S Hu, M Huang, PK Nguyen, Y Gong, Z Li, F Jia, F Lan, J Liu, D Nag, ... Circulation 124 (11_suppl_1), S27-S34, 2011 | 181 | 2011 |
Mortalin–p53 interaction in cancer cells is stress dependent and constitutes a selective target for cancer therapy WJ Lu, NP Lee, SC Kaul, F Lan, RTP Poon, R Wadhwa, JM Luk Cell Death & Differentiation 18 (6), 1046-1056, 2011 | 176 | 2011 |
Human Cardiac Progenitor Cells Engineered With Pim-I Kinase Enhance Myocardial Repair S Mohsin, M Khan, H Toko, B Bailey, CT Cottage, K Wallach, D Nag, ... Journal of the American College of Cardiology, 2012 | 173 | 2012 |
MicroRNA-302 increases reprogramming efficiency via repression of NR2F2 S Hu, KD Wilson, Z Ghosh, L Han, Y Wang, F Lan, KJ Ransohoff, ... Stem cells 31 (2), 259-268, 2013 | 172 | 2013 |
The role of SIRT6 protein in aging and reprogramming of human induced pluripotent stem cells A Sharma, S Diecke, WY Zhang, F Lan, C He, NM Mordwinkin, KF Chua, ... Journal of Biological Chemistry 288 (25), 18439-18447, 2013 | 151 | 2013 |
Effect of human donor cell source on differentiation and function of cardiac induced pluripotent stem cells V Sanchez-Freire, AS Lee, S Hu, OJ Abilez, P Liang, F Lan, BC Huber, ... Journal of the American College of Cardiology 64 (5), 436-448, 2014 | 138 | 2014 |
Human AML-iPSCs reacquire leukemic properties after differentiation and model clonal variation of disease MP Chao, AJ Gentles, S Chatterjee, F Lan, A Reinisch, MR Corces, ... Cell stem cell 20 (3), 329-344. e7, 2017 | 135 | 2017 |
β-Aminopropionitrile monofumarate induces thoracic aortic dissection in C57BL/6 mice W Ren, Y Liu, X Wang, L Jia, C Piao, F Lan, J Du Scientific reports 6 (1), 28149, 2016 | 130 | 2016 |
Characterization of the molecular mechanisms underlying increased ischemic damage in the aldehyde dehydrogenase 2 genetic polymorphism using a human … AD Ebert, K Kodo, P Liang, H Wu, BC Huber, J Riegler, J Churko, J Lee, ... Science translational medicine 6 (255), 255ra130-255ra130, 2014 | 118 | 2014 |
Stem cell-derived cell sheet transplantation for heart tissue repair in myocardial infarction R Guo, M Morimatsu, T Feng, F Lan, D Chang, F Wan, Y Ling Stem Cell Research & Therapy 11, 1-13, 2020 | 112 | 2020 |
Preclinical derivation and imaging of autologously transplanted canine induced pluripotent stem cells AS Lee, D Xu, JR Plews, PK Nguyen, D Nag, JK Lyons, L Han, S Hu, ... Journal of Biological Chemistry 286 (37), 32697-32704, 2011 | 112 | 2011 |