| Drosophila tools and assays for the study of human diseases B Ugur, K Chen, HJ Bellen Disease models & mechanisms 9 (3), 235-244, 2016 | 542 | 2016 |
| ALS-implicated protein TDP-43 sustains levels of STMN2, a mediator of motor neuron growth and repair JR Klim, LA Williams, F Limone, I Guerra San Juan, BN Davis-Dusenbery, ... Nature neuroscience 22 (2), 167-179, 2019 | 449 | 2019 |
| A library of MiMICs allows tagging of genes and reversible, spatial and temporal knockdown of proteins in Drosophila S Nagarkar-Jaiswal, PT Lee, ME Campbell, K Chen, S Anguiano-Zarate, ... elife 4, e05338, 2015 | 408 | 2015 |
| A drosophila genetic resource of mutants to study mechanisms underlying human genetic diseases S Yamamoto, M Jaiswal, WL Charng, T Gambin, E Karaca, G Mirzaa, ... Cell 159 (1), 200-214, 2014 | 406 | 2014 |
| Phospholipase PLA2G6, a parkinsonism-associated gene, affects Vps26 and Vps35, retromer function, and ceramide levels, similar to α-synuclein gain G Lin, PT Lee, K Chen, D Mao, KL Tan, Z Zuo, WW Lin, L Wang, HJ Bellen Cell metabolism 28 (4), 605-618. e6, 2018 | 151 | 2018 |
| Mitochondrial fusion but not fission regulates larval growth and synaptic development through steroid hormone production H Sandoval, CK Yao, K Chen, M Jaiswal, T Donti, YQ Lin, V Bayat, ... Elife 3, e03558, 2014 | 114 | 2014 |
| Drosophila neuroligin 2 is required presynaptically and postsynaptically for proper synaptic differentiation and synaptic transmission YC Chen, YQ Lin, S Banerjee, K Venken, J Li, A Ismat, K Chen, L Duraine, ... Journal of neuroscience 32 (45), 16018-16030, 2012 | 80 | 2012 |
| Loss of Frataxin induces iron toxicity, sphingolipid synthesis, and Pdk1/Mef2 activation, leading to neurodegeneration K Chen, G Lin, NA Haelterman, TSY Ho, T Li, Z Li, L Duraine, BH Graham, ... Elife 5, e16043, 2016 | 79 | 2016 |
| A TRPV channel in Drosophila motor neurons regulates presynaptic resting Ca2+ levels, synapse growth, and synaptic transmission CO Wong, K Chen, YQ Lin, Y Chao, L Duraine, Z Lu, WH Yoon, ... Neuron 84 (4), 764-777, 2014 | 73 | 2014 |
| Loss of Frataxin activates the iron/sphingolipid/PDK1/Mef2 pathway in mammals K Chen, TSY Ho, G Lin, KL Tan, MN Rasband, HJ Bellen Elife 5, e20732, 2016 | 67 | 2016 |
| Drosophila Tempura, a Novel Protein Prenyltransferase α Subunit, Regulates Notch Signaling Via Rab1 and Rab11 WL Charng, S Yamamoto, M Jaiswal, V Bayat, B Xiong, K Zhang, ... PLoS biology 12 (1), e1001777, 2014 | 53 | 2014 |
| Human amyotrophic lateral sclerosis excitability phenotype screen: Target discovery and validation X Huang, KCD Roet, L Zhang, A Brault, AP Berg, AB Jefferson, ... Cell reports 35 (10), 2021 | 41 | 2021 |
| Ubr3, a novel modulator of Hh signaling affects the degradation of Costal-2 and Kif7 through poly-ubiquitination T Li, J Fan, B Blanco-Sánchez, N Giagtzoglou, G Lin, S Yamamoto, ... PLoS Genetics 12 (5), e1006054, 2016 | 18 | 2016 |
| Role of a propeller loop in the quaternary structure and enzymatic activity of prolyl dipeptidases DPP-IV and DPP9 HK Tang, KC Chen, GG Liou, SC Cheng, CH Chien, HY Tang, LH Huang, ... Febs Letters 585 (21), 3409-3414, 2011 | 15 | 2011 |
| Screening for axon regeneration promoting compounds with human iPSC-derived motor neurons TSY Ho, JT Hees, Z Xu, R Kawaguchi, NP Biscola, DG Taub, K Chen, ... bioRxiv, 2021.11. 02.466937, 2021 | 3 | 2021 |
| Identification of novel neuroprotectants against vincristine-induced neurotoxicity in iPSC-derived neurons V Petrova, AR Snavely, J Splaine, S Zhen, B Singh, R Pandey, K Chen, ... Cellular and Molecular Life Sciences 81 (1), 1-12, 2024 | | 2024 |
| Downregulation of the silent potassium channel Kv8. 1 increases motor neuron vulnerability in amyotrophic lateral sclerosis X Huang, S Lee, K Chen, R Kawaguchi, O Wiskow, S Ghosh, D Frost, ... Brain Communications, fcae202, 2024 | | 2024 |
| NEK1 modulates neurite outgrowth in motor neurons through coordinating retromer formation X Huang, JA Oses, R Kawaguchi, L Perrault, D Frost, K Chen, F Guo, ... bioRxiv, 2024.05. 06.592854, 2024 | | 2024 |
| Downregulation of the silent potassium channel Kv8. 1 increases ALS motor neuron vulnerability X Huang, S Lee, R Kawaguchi, O Wiskow, S Ghosh, D Frost, L Perrault, ... bioRxiv, 2023.05. 07.539778, 2023 | | 2023 |
| A TRPV Channel in Drosophila Motor Neurons Regulates Presynaptic Resting Ca 2 Levels, Synapse Growth, and Synaptic Transmission CO Wong, YQ Lin, K Chen, Y Chao, L Duraine, WH Yoon, JM Sullivan, ... | | |
