| A new class of potent matrix metalloproteinase 13 inhibitors for potential treatment of osteoarthritis: Evidence of histologic and clinical efficacy without musculoskeletal … VM Baragi, G Becher, AM Bendele, R Biesinger, H Bluhm, J Boer, H Deng, ... Arthritis & Rheumatism: Official Journal of the American College of …, 2009 | 225 | 2009 |
| Closing the gap: identification of human 3-ketosteroid reductase, the last unknown enzyme of mammalian cholesterol biosynthesis Z Marijanovic, D Laubner, G Moller, C Gege, B Husen, J Adamski, ... Molecular endocrinology 17 (9), 1715-1725, 2003 | 170 | 2003 |
| Synthesis and biological evaluation of α-ketoamides as inhibitors of the Dengue virus protease with antiviral activity in cell-culture C Steuer, C Gege, W Fischl, KH Heinonen, R Bartenschlager, CD Klein Bioorganic & medicinal chemistry 19 (13), 4067-4074, 2011 | 161 | 2011 |
| Extra Binding Region Induced by Non-Zinc Chelating Inhibitors into the S1′ Subsite of Matrix Metalloproteinase 8 (MMP-8) G Pochetti, R Montanari, C Gege, C Chevrier, AG Taveras, F Mazza Journal of medicinal chemistry 52 (4), 1040-1049, 2009 | 94 | 2009 |
| Calcium‐Dependent Carbohydrate–Carbohydrate Recognition between LewisX Blood Group Antigens A Geyer, C Gege, RR Schmidt Angewandte Chemie International Edition 39 (18), 3245-3249, 2000 | 79 | 2000 |
| Nonsteroidal FXR ligands: current status and clinical applications C Gege, E Hambruch, N Hambruch, O Kinzel, C Kremoser Bile Acids and Their Receptors, 167-205, 2019 | 78 | 2019 |
| Discovery and evaluation of a non-Zn chelating, selective matrix metalloproteinase 13 (MMP-13) inhibitor for potential intra-articular treatment of osteoarthritis C Gege, B Bao, H Bluhm, J Boer, BM Gallagher Jr, B Korniski, TS Powers, ... Journal of medicinal chemistry 55 (2), 709-716, 2012 | 76 | 2012 |
| Carbohydrate–Carbohydrate Recognition between LewisX Glycoconjugates A Geyer, C Gege, RR Schmidt Angewandte Chemie International Edition 38 (10), 1466-1468, 1999 | 76 | 1999 |
| Knocking on FXR´s Door: The "Hammerhead"-Structure Series of FXR Agonists – Amphiphilic Isoxazoles with Potent In Vitro and In Vivo Activities C Gege, O Kinzel, C Steeneck, A Schulz, C Kremoser Current topics in medicinal chemistry 14 (19), 2143-2158, 2014 | 71 | 2014 |
| Synthesis of the sialyl Lewis X epitope attached to glycolipids with different core structures and their selectin‐binding characteristics in a dynamic test system C Gege, J Vogel, G Bendas, U Rothe, RR Schmidt Chemistry–A European Journal 6 (1), 111-122, 2000 | 67 | 2000 |
| Adhesion of Giant Vesicles Mediated by Weak Binding of Sialyl-LewisX to E-Selectin in the Presence of Repelling Poly(ethylene glycol) Molecules BG Lorz, AS Smith, C Gege, E Sackmann Langmuir 23 (24), 12293-12300, 2007 | 57 | 2007 |
| Structure-based design, synthesis and in vitro characterization of potent 17β-hydroxysteroid dehydrogenase type 1 inhibitors based on 2-substitutions of estrone and D-homo-estrone G Möller, D Deluca, C Gege, A Rosinus, D Kowalik, O Peters, ... Bioorganic & medicinal chemistry letters 19 (23), 6740-6744, 2009 | 54 | 2009 |
| RORγt inhibitors as potential back-ups for the phase II candidate VTP-43742 from Vitae Pharmaceuticals: patent evaluation of WO2016061160 and US20160122345 C Gege Expert Opinion on Therapeutic Patents 27 (1), 1-8, 2017 | 52 | 2017 |
| Retinoic acid-related orphan receptor gamma t (RORγt) inverse agonists/antagonists for the treatment of inflammatory diseases–where are we presently? C Gege Expert Opinion on Drug Discovery 16 (12), 1517-1535, 2021 | 48 | 2021 |
| Retinoid-related orphan receptor gamma t (RORγt) inhibitors from Vitae Pharmaceuticals (WO2015116904) and structure proposal for their Phase I candidate VTP-43742 C Gege Expert Opinion on Therapeutic Patents 26 (6), 737-744, 2016 | 47 | 2016 |
| Membrane adhesion via homophilic saccharide-saccharide interactions investigated by neutron scattering E Schneck, B Demé, C Gege, M Tanaka Biophysical journal 100 (9), 2151-2159, 2011 | 47 | 2011 |
| Heterobicyclic metalloprotease inhibitors B Nolte, I Sucholeiki, T Feuerstein, BM Gallagher, X Wu, C Steeneck, ... US Patent App. 11/986,622, 2008 | 40 | 2008 |
| Synthesis of fluorescence labeled sialyl LewisX glycosphingolipids C Gege, S Oscarson, RR Schmidt Tetrahedron letters 42 (3), 377-380, 2001 | 40 | 2001 |
| Novel substituted isoxazole FXR agonists with cyclopropyl, hydroxycyclobutyl and hydroxyazetidinyl linkers: Understanding and improving key determinants of pharmacological … O Kinzel, C Steeneck, T Schlüter, A Schulz, C Gege, U Hahn, E Hambruch, ... Bioorganic & Medicinal Chemistry Letters 26 (15), 3746-3753, 2016 | 38 | 2016 |
| Modulation of intermembrane interaction and bending rigidity of biomembrane models via carbohydrates investigated by specular and off-specular neutron scattering E Schneck, F Rehfeldt, RG Oliveira, C Gege, B Demé, M Tanaka Physical Review E 78 (6), 061924, 2008 | 38 | 2008 |
Motomu TanakaHeidelberg University在 uni-heidelberg.de 的电子邮件经过验证
