TimeLapse-seq: adding a temporal dimension to RNA sequencing through nucleoside recoding JA Schofield, EE Duffy, L Kiefer, MC Sullivan, MD Simon Nature methods 15 (3), 221-225, 2018 | 223 | 2018 |
p53 activates the long noncoding RNA Pvt1b to inhibit Myc and suppress tumorigenesis CE Olivero, E Martínez-Terroba, J Zimmer, C Liao, E Tesfaye, ... Molecular cell 77 (4), 761-774. e8, 2020 | 127 | 2020 |
Gaining insight into transcriptome‐wide RNA population dynamics through the chemistry of 4‐thiouridine EE Duffy, JA Schofield, MD Simon Wiley Interdisciplinary Reviews: RNA 10 (1), e1513, 2019 | 44 | 2019 |
Expanding the nucleoside recoding toolkit: revealing RNA population dynamics with 6-thioguanosine L Kiefer, JA Schofield, MD Simon Journal of the American Chemical Society 140 (44), 14567-14570, 2018 | 38 | 2018 |
The NBDY microprotein regulates cellular RNA decapping Z Na, Y Luo, JA Schofield, S Smelyansky, A Khitun, S Muthukumar, ... Biochemistry 59 (42), 4131-4142, 2020 | 35 | 2020 |
Global profiling of cellular substrates of human Dcp2 Y Luo, JA Schofield, MD Simon, SA Slavoff Biochemistry 59 (43), 4176-4188, 2020 | 23 | 2020 |
Structural and Spectroscopic Characterization of Iron(II), Cobalt(II), and Nickel(II) ortho-Dihalophenolate Complexes: Insights into Metal–Halogen Secondary Bonding TE Machonkin, MD Boshart, JA Schofield, MM Rodriguez, K Grubel, ... Inorganic Chemistry 53 (18), 9837-9848, 2014 | 18 | 2014 |
Discovery of cellular substrates of human RNA-decapping enzyme DCP2 using a stapled bicyclic peptide inhibitor Y Luo, JA Schofield, Z Na, T Hann, MD Simon, SA Slavoff Cell chemical biology 28 (4), 463-474. e7, 2021 | 14 | 2021 |
Broad compatibility between yeast UAS elements and core promoters and identification of promoter elements that determine cofactor specificity JA Schofield, S Hahn Cell Reports 42 (4), 2023 | 6 | 2023 |
Metal–Halogen Secondary Bonding in a 2, 5‐Dichlorohydroquinonate Cobalt (II) Complex: Insight into Substrate Coordination in the Chlorohydroquinone Dioxygenase PcpA JA Schofield, WW Brennessel, E Urnezius, D Rokhsana, MD Boshart, ... European Journal of Inorganic Chemistry 2015 (28), 4643-4647, 2015 | 3 | 2015 |
Improving the study of RNA dynamics through advances in RNA-seq with metabolic labeling and nucleotide-recoding chemistry JT Zimmer, IW Vock, JA Schofield, L Kiefer, MH Moon, MD Simon bioRxiv, 2023 | 2 | 2023 |
Time lapse sequencing: a convertible-nucleoside approach to enrichment-free analysis of RNA dynamics M Simon, J Schofield US Patent 11,098,342, 2021 | 2 | 2021 |
Transcriptional bursting, gene activation, and roles of SAGA and Mediator Tail measured using nucleotide recoding single cell RNA-seq JA Schofield, S Hahn bioRxiv, 2024.03. 08.584165, 2024 | | 2024 |
Broad compatibility between yeast UAS elements and core promoters and identification of promoter elements that determine cofactor specificity JA Schofield, S Hahn bioRxiv, 2022.11. 03.515066, 2022 | | 2022 |
TimeLapse-seq: Examining the Dynamics of the Transcriptome through 4-Thiouridine Nucleoside Recoding JA Schofield Yale University, 2020 | | 2020 |
Protocol for TimeLapse-seq M Simon, M Sullivan, J Schofield, E Duffy, L Kiefer | | 2018 |
Studying Stimulus‐Induced Changes in RNA Dynamics by Mutational Mapping through TimeLapse‐seq L Kiefer, JA Schofield, MD Simon The FASEB Journal 32, lb23-lb23, 2018 | | 2018 |
Exploring the substrate specificity of the 2, 6-dichlorohydroquinone ring-cleaving dioxygenase PcpA through biochemical and model chemistry approaches TE Machonkin, M Boshart, J Schofield, D Rokhsana, MQ Paulson, ... JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY 19, S299-S299, 2014 | | 2014 |
Metal-halogen secondary bonding in iron (II), cobalt (II), and nickel (II) 2, 6-dihalophenolate complexes: Insights into the substrate specificity of the hydroquinone … TE Machonkin, M Boshart, J Schofield, PL Holland, D Rokhsana Abstracts of Papers of the American Chemical Society 245, 2013 | | 2013 |
Examination of the substrate specificity of the enzyme PcpA using synthetic model complexes J Schofield, TE Machonkin, PL Holland ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 245, 2013 | | 2013 |