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Leo Pallanck
Leo Pallanck
Professor of Genome Sciences, University of Washington
在 uw.edu 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
Mitochondrial pathology and apoptotic muscle degeneration in Drosophila parkin mutants
JC Greene, AJ Whitworth, I Kuo, LA Andrews, MB Feany, LJ Pallanck
Proceedings of the National Academy of Sciences 100 (7), 4078-4083, 2003
14342003
The PINK1/Parkin pathway regulates mitochondrial morphology
AC Poole, RE Thomas, LA Andrews, HM McBride, AJ Whitworth, ...
Proceedings of the National Academy of Sciences 105 (5), 1638-1643, 2008
10352008
Functional role of the β subunit of high conductance calcium-activated potassium channels
OB McManus, LMH Helms, L Pallanck, B Ganetzky, R Swanson, ...
Neuron 14 (3), 645-650, 1995
5591995
The mitochondrial fusion-promoting factor mitofusin is a substrate of the PINK1/parkin pathway
AC Poole, RE Thomas, S Yu, ES Vincow, L Pallanck
PloS one 5 (4), e10054, 2010
5042010
The PINK1–Parkin pathway promotes both mitophagy and selective respiratory chain turnover in vivo
ES Vincow, G Merrihew, RE Thomas, NJ Shulman, RP Beyer, ...
Proceedings of the National Academy of Sciences 110 (16), 6400-6405, 2013
5012013
Increased glutathione S-transferase activity rescues dopaminergic neuron loss in a Drosophila model of Parkinson's disease
AJ Whitworth, DA Theodore, JC Greene, H Beneš, PD Wes, LJ Pallanck
Proceedings of the National Academy of Sciences 102 (22), 8024-8029, 2005
4832005
Drosophila DJ-1 mutants are selectively sensitive to environmental toxins associated with Parkinson’s disease
M Meulener, AJ Whitworth, CE Armstrong-Gold, P Rizzu, P Heutink, ...
Current Biology 15 (17), 1572-1577, 2005
4252005
VCP is essential for mitochondrial quality control by PINK1/Parkin and this function is impaired by VCP mutations
NC Kim, E Tresse, RM Kolaitis, A Molliex, RE Thomas, NH Alami, B Wang, ...
Neuron 78 (1), 65-80, 2013
2612013
Genetic and genomic studies of Drosophila parkin mutants implicate oxidative stress and innate immune responses in pathogenesis
JC Greene, AJ Whitworth, LA Andrews, TJ Parker, LJ Pallanck
Human molecular genetics 14 (6), 799-811, 2005
2352005
Cloning and characterization of human and mouse homologs of the Drosophila calcium-activated potassium channel gene, slowpoke
L Pallanck, B Ganetzky
Human molecular genetics 3 (8), 1239-1243, 1994
2331994
Ataxin-2 and its Drosophila homolog, ATX2, physically assemble with polyribosomes
TF Satterfield, LJ Pallanck
Human molecular genetics 15 (16), 2523-2532, 2006
2312006
Oxidative stress is not a major contributor to somatic mitochondrial DNA mutations
LS Itsara, SR Kennedy, EJ Fox, S Yu, JJ Hewitt, M Sanchez-Contreras, ...
PLoS genetics 10 (2), e1003974, 2014
1952014
Induction of the phase II detoxification pathway suppresses neuron loss in Drosophila models of Parkinson's disease
K Trinh, K Moore, PD Wes, PJ Muchowski, J Dey, L Andrews, LJ Pallanck
Journal of Neuroscience 28 (2), 465-472, 2008
1822008
PINK1/Parkin mitophagy and neurodegeneration—what do we really know in vivo?
AJ Whitworth, LJ Pallanck
Current opinion in genetics & development 44, 47-53, 2017
1702017
A Drosophila Homolog of the Polyglutamine Disease Gene SCA2 Is a Dosage-Sensitive Regulator of Actin Filament Formation
TF Satterfield, SM Jackson, LJ Pallanck
Genetics 162 (4), 1687-1702, 2002
1672002
The PINK1/Parkin pathway: a mitochondrial quality control system?
AJ Whitworth, LJ Pallanck
Journal of bioenergetics and biomembranes 41, 499-503, 2009
1592009
Drosophila models pioneer a new approach to drug discovery for Parkinson's disease
AJ Whitworth, PD Wes, LJ Pallanck
Drug discovery today 11 (3-4), 119-126, 2006
1552006
Parkin: a multipurpose neuroprotective agent?
MB Feany, LJ Pallanck
Neuron 38 (1), 13-16, 2003
1532003
Decaffeinated coffee and nicotine-free tobacco provide neuroprotection in Drosophila models of Parkinson's disease through an NRF2-dependent mechanism
K Trinh, L Andrews, J Krause, T Hanak, D Lee, M Gelb, L Pallanck
Journal of Neuroscience 30 (16), 5525-5532, 2010
1452010
PINK1-Parkin pathway activity is regulated by degradation of PINK1 in the mitochondrial matrix
RE Thomas, LA Andrews, JL Burman, WY Lin, LJ Pallanck
PLoS genetics 10 (5), e1004279, 2014
1422014
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