| Complex oscillatory waves emerging from cortical organoids model early human brain network development CA Trujillo, R Gao, PD Negraes, J Gu, J Buchanan, S Preissl, A Wang, ... Cell stem cell 25 (4), 558-569. e7, 2019 | 667 | 2019 |
| Elimination of toxic microsatellite repeat expansion RNA by RNA-targeting Cas9 R Batra, DA Nelles, E Pirie, SM Blue, RJ Marina, H Wang, IA Chaim, ... Cell 170 (5), 899-912. e10, 2017 | 293 | 2017 |
| Multiplexed DNA repair assays for multiple lesions and multiple doses via transcription inhibition and transcriptional mutagenesis ZD Nagel, CM Margulies, IA Chaim, SK McRee, P Mazzucato, A Ahmad, ... Proceedings of the National Academy of Sciences 111 (18), E1823-E1832, 2014 | 140 | 2014 |
| Reintroduction of the archaic variant of NOVA1 in cortical organoids alters neurodevelopment CA Trujillo, ES Rice, NK Schaefer, IA Chaim, EC Wheeler, AA Madrigal, ... Science 371 (6530), eaax2537, 2021 | 128 | 2021 |
| DNA repair capacity in multiple pathways predicts chemoresistance in glioblastoma multiforme ZD Nagel, GJ Kitange, SK Gupta, BA Joughin, IA Chaim, P Mazzucato, ... Cancer research 77 (1), 198-206, 2017 | 125 | 2017 |
| Inhibition of YTHDF2 triggers proteotoxic cell death in MYC-driven breast cancer JM Einstein, M Perelis, IA Chaim, JK Meena, JK Nussbacher, AT Tankka, ... Molecular cell 81 (15), 3048-3064. e9, 2021 | 115 | 2021 |
| Robust single-cell discovery of RNA targets of RNA-binding proteins and ribosomes KW Brannan, IA Chaim, RJ Marina, BA Yee, ER Kofman, DA Lorenz, ... Nature methods 18 (5), 507-519, 2021 | 94 | 2021 |
| Inter-individual variation in DNA repair capacity: a need for multi-pathway functional assays to promote translational DNA repair research ZD Nagel, IA Chaim, LD Samson DNA repair 19, 199-213, 2014 | 85 | 2014 |
| Longitudinal assessment of tumor development using cancer avatars derived from genetically engineered pluripotent stem cells T Koga, IA Chaim, JA Benitez, S Markmiller, AD Parisian, RF Hevner, ... Nature communications 11 (1), 550, 2020 | 53 | 2020 |
| In vivo measurements of interindividual differences in DNA glycosylases and APE1 activities IA Chaim, ZD Nagel, JJ Jordan, P Mazzucato, LD Samson Proceedings of the National Academy of Sciences 114 (48), E10379-E10388, 2017 | 52 | 2017 |
| Evaluation of the potential of novel PCL–PPDX biodegradable scaffolds as support materials for cartilage tissue engineering IA Chaim, MA Sabino, M Mendt, AJ Müller, D Ajami Journal of tissue engineering and regenerative medicine 6 (4), 272-279, 2012 | 28 | 2012 |
| Nitric oxide induced S-nitrosation causes base excision repair imbalance MC Parrish, IA Chaim, ZD Nagel, SR Tannenbaum, LD Samson, ... DNA repair 68, 25-33, 2018 | 21 | 2018 |
| A novel role for transcription-coupled nucleotide excision repair for the in vivo repair of 3,N4-ethenocytosine IA Chaim, A Gardner, J Wu, T Iyama, DM Wilson III, LD Samson Nucleic Acids Research 45 (6), 3242-3252, 2017 | 19 | 2017 |
| CometChip analysis of human primary lymphocytes enables quantification of inter-individual differences in the kinetics of repair of oxidative DNA damage LP Ngo, S Kaushal, IA Chaim, P Mazzucato, C Ricciardi, LD Samson, ... Free Radical Biology and Medicine 174, 89-99, 2021 | 11 | 2021 |
| MECP2-related pathways are dysregulated in a cortical organoid model of myotonic dystrophy KH Morelli, W Jin, S Shathe, AA Madrigal, KL Jones, JL Schwartz, ... Science translational medicine 14 (651), eabn2375, 2022 | 10 | 2022 |
| Alkylation induced cerebellar degeneration dependent on Aag and Parp1 does not occur via previously established cell death mechanisms CM Margulies, IA Chaim, A Mazumder, J Criscione, LD Samson PloS one 12 (9), e0184619, 2017 | 7 | 2017 |
| Assessing BER capacity in the human population IA Chaim, ZD Nagel The Base Excision Repair Pathway: Molecular Mechanisms and Role in Disease …, 2017 | 2 | 2017 |
Gene Yeo PhD MBAProfessor of Cellular and Molecular Medicine at UC San Diego在 ucsd.edu 的电子邮件经过验证
