Tumor heterogeneity correlates with less immune response and worse survival in breast cancer patients KA McDonald, T Kawaguchi, Q Qi, X Peng, M Asaoka, J Young, ... Annals of surgical oncology 26, 2191-2199, 2019 | 163 | 2019 |
CXCL12/CXCR4 blockade by oncolytic virotherapy inhibits ovarian cancer growth by decreasing immunosuppression and targeting cancer-initiating cells M Gil, MP Komorowski, M Seshadri, H Rokita, AJR McGray, M Opyrchal, ... The Journal of Immunology 193 (10), 5327-5337, 2014 | 162 | 2014 |
The mitotic kinase Aurora-A promotes distant metastases by inducing epithelial-to-mesenchymal transition in ERα+ breast cancer cells AB D'assoro, C Quatraro, A Amato, M Opyrchal, A Leontovich, Y Ikeda, ... Oncogene 33 (5), 599-610, 2014 | 147 | 2014 |
Clinical trials with oncolytic measles virus: current status and future prospects P Msaouel, M Opyrchal, A Dispenzieri, K Whye Peng, M J. Federspiel, ... Current cancer drug targets 18 (2), 177-187, 2018 | 139 | 2018 |
Oncolytic measles virus strains have significant antitumor activity against glioma stem cells C Allen, M Opyrchal, I Aderca, MA Schroeder, JN Sarkaria, E Domingo, ... Gene therapy 20 (4), 444-449, 2013 | 101 | 2013 |
Oncolytic measles virus strains as novel anticancer agents P Msaouel, M Opyrchal, E Domingo Musibay, E Galanis Expert opinion on biological therapy 13 (4), 483-502, 2013 | 90 | 2013 |
The 3′ untranslated region of sindbis virus represses deadenylation of viral transcripts in mosquito and Mammalian cells NL Garneau, KJ Sokoloski, M Opyrchal, CP Neff, CJ Wilusz, J Wilusz Journal of virology 82 (2), 880-892, 2008 | 88 | 2008 |
Entinostat plus pembrolizumab in patients with metastatic NSCLC previously treated with anti–PD-(L) 1 therapy MD Hellmann, PA Jänne, M Opyrchal, N Hafez, LE Raez, DI Gabrilovich, ... Clinical Cancer Research 27 (4), 1019-1028, 2021 | 79 | 2021 |
Primary and secondary breast angiosarcoma: single center report and a meta-analysis Y Abdou, A Elkhanany, K Attwood, W Ji, K Takabe, M Opyrchal Breast Cancer Research and Treatment 178, 523-533, 2019 | 78 | 2019 |
Dephosphorylation of HuR protein during alphavirus infection is associated with HuR relocalization to the cytoplasm AM Dickson, JR Anderson, MD Barnhart, KJ Sokoloski, L Oko, M Opyrchal, ... Journal of Biological Chemistry 287 (43), 36229-36238, 2012 | 72 | 2012 |
Effective radiovirotherapy for malignant gliomas by using oncolytic measles virus strains encoding the sodium iodide symporter (MV-NIS) M Opyrchal, C Allen, I Iankov, I Aderca, M Schroeder, J Sarkaria, ... Human gene therapy 23 (4), 419-427, 2012 | 67 | 2012 |
Inhibition of Cdk2 kinase activity selectively targets the CD44+/CD24-/Low stem-like subpopulation and restores chemosensitivity of SUM149PT triple-negative breast cancer cells M Opyrchal, JL Salisbury, I Iankov, MP Goetz, J McCubrey, MW Gambino, ... International journal of oncology 45 (3), 1193-1199, 2014 | 64 | 2014 |
Prognostic significance of stromal versus intratumoral infiltrating lymphocytes in different subtypes of breast cancer treated with cytotoxic neoadjuvant chemotherapy T Khoury, V Nagrale, M Opyrchal, X Peng, D Wang, S Yao Applied Immunohistochemistry & Molecular Morphology 26 (8), 523-532, 2018 | 62 | 2018 |
Chimeric antigen receptor-T cells for targeting solid tumors: current challenges and existing strategies L Springuel, C Lonez, B Alexandre, E Van Cutsem, JPH Machiels, ... BioDrugs 33, 515-537, 2019 | 60 | 2019 |
Phase I clinical trial of locoregional administration of the oncolytic adenovirus ONYX-015 in combination with mitomycin-C, doxorubicin, and cisplatin chemotherapy in patients … M Opyrchal, I Aderca, E Galanis Gene Therapy of Cancer: Methods and Protocols, 705-717, 2009 | 57 | 2009 |
Contribution of immune cells to glucocorticoid receptor expression in breast cancer S Gandhi, A Elkhanany, M Oshi, T Dai, M Opyrchal, H Mohammadpour, ... International journal of molecular sciences 21 (13), 4635, 2020 | 43 | 2020 |
High MYC mRNA expression is more clinically relevant than MYC DNA amplification in triple-negative breast cancer E Katsuta, L Yan, T Takeshita, KA McDonald, S Dasgupta, M Opyrchal, ... International journal of molecular sciences 21 (1), 217, 2019 | 43 | 2019 |
Efficacy and safety of entinostat (ENT) and pembrolizumab (PEMBRO) in patients with melanoma previously treated with anti-PD1 therapy RJ Sullivan, SJ Moschos, ML Johnson, M Opyrchal, P Ordentlich, ... Cancer Res 79 (13), CT072, 2019 | 39 | 2019 |
Aurora-A mitotic kinase induces endocrine resistance through down-regulation of ERα expression in initially ERα+ breast cancer cells M Opyrchal, JL Salisbury, S Zhang, J McCubrey, J Hawse, MP Goetz, ... PloS one 9 (5), e96995, 2014 | 37 | 2014 |
A cell-free mRNA stability assay reveals conservation of the enzymes and mechanisms of mRNA decay between mosquito and mammalian cell lines M Opyrchal, JR Anderson, KJ Sokoloski, CJ Wilusz, J Wilusz Insect biochemistry and molecular biology 35 (12), 1321-1334, 2005 | 36 | 2005 |