| Glucagon-like peptide I stimulates insulin gene expression and increases cyclic AMP levels in a rat islet cell line. DJ Drucker, J Philippe, S Mojsov, WL Chick, JF Habener Proceedings of the National Academy of Sciences 84 (10), 3434-3438, 1987 | 1150 | 1987 |
| The insulin gene promoter: a simplified nomenclature M German, S Ashcroft, K Docherty, H Edlund, T Edlund, S Goodison, ... Diabetes 44 (8), 1002-1004, 1995 | 243 | 1995 |
| Pdx1 level defines pancreatic gene expression pattern and cell lineage differentiation H Wang, P Maechler, B Ritz-Laser, KA Hagenfeldt, H Ishihara, J Philippe, ... Journal of Biological Chemistry 276 (27), 25279-25286, 2001 | 223 | 2001 |
| Agenesis of human pancreas due to decreased half-life of insulin promoter factor 1 VM Schwitzgebel, A Mamin, T Brun, B Ritz-Laser, M Zaiko, A Maret, ... The Journal of Clinical Endocrinology & Metabolism 88 (9), 4398-4406, 2003 | 209 | 2003 |
| HUMAN ISLET TRANSPLANTATION: Lessons from 13 Autologous and 13 Allogeneic Transplantations: 1, 2 J Oberholzer, F Triponez, R Mage, E Andereggen, L Bühler, N Crétin, ... Transplantation 69 (6), 1115-1123, 2000 | 205 | 2000 |
| Peptones stimulate both the secretion of the incretin hormone glucagon-like peptide 1 and the transcription of the proglucagon gene. M Cordier-Bussat, C Bernard, F Levenez, N Klages, B Laser-Ritz, ... Diabetes 47 (7), 1038-1045, 1998 | 205 | 1998 |
| Ablation of islet endocrine cells by targeted expression of hormone-promoter-driven toxigenes. PL Herrera, J Huarte, R Zufferey, A Nichols, B Mermillod, J Philippe, ... Proceedings of the National Academy of Sciences 91 (26), 12999-13003, 1994 | 176 | 1994 |
| Identification of nine novel mutations in the hepatocyte nuclear factor 1 alpha gene associated with maturity-onset diabetes of the young (MODY3) M Vaxillaire, M Rouard, K Yamagata, N Oda, PJ Kaisaki, VV Boriraj, ... Human molecular genetics 6 (4), 583-586, 1997 | 168 | 1997 |
| Non-alcoholic fatty liver disease and insulin resistance: from bench to bedside K Gariani, J Philippe, FR Jornayvaz Diabetes & metabolism 39 (1), 16-26, 2013 | 160 | 2013 |
| Insulin regulation of the glucagon gene is mediated by an insulin-responsive DNA element. J Philippe Proceedings of the National Academy of Sciences 88 (16), 7224-7227, 1991 | 157 | 1991 |
| Alpha-cell-specific expression of the glucagon gene is conferred to the glucagon promoter element by the interactions of DNA-binding proteins J Philippe, DJ Drucker, W Knepel, L Jepeal, Z Misulovin, JF Habener Molecular and cellular biology 8 (11), 4877-4888, 1988 | 155 | 1988 |
| Glucose-induced preproinsulin gene expression is inhibited by the free fatty acid palmitate B Ritz-Laser, P Meda, I Constant, N Klages, A Charollais, A Morales, ... Endocrinology 140 (9), 4005-4014, 1999 | 148 | 1999 |
| Adequate connexin-mediated coupling is required for proper insulin production. C Vozzi, S Ullrich, A Charollais, J Philippe, L Orci, P Meda The Journal of cell biology 131 (6), 1561-1572, 1995 | 148 | 1995 |
| Multipotential phenotypic expression of genes encoding peptide hormones in rat insulinoma cell lines. J Philippe, WL Chick, JF Habener The Journal of clinical investigation 79 (2), 351-358, 1987 | 144 | 1987 |
| Pax6 is crucial for β-cell function, insulin biosynthesis, and glucose-induced insulin secretion Y Gosmain, LS Katz, MH Masson, C Cheyssac, C Poisson, J Philippe Molecular endocrinology 26 (4), 696-709, 2012 | 140 | 2012 |
| Functional characterization of a cAMP-responsive element of the rat insulin I gene. J Philippe, M Missotten Journal of Biological Chemistry 265 (3), 1465-1469, 1990 | 134 | 1990 |
| Treating type 2 diabetes: how safe are current therapeutic agents? J Philippe, D Raccah International Journal of Clinical Practice 63 (2), 321-332, 2009 | 132 | 2009 |
| Bone and renal components in hypercalcemia of malignancy and responses to a single infusion of clodronate JP Bonjour, J Philippe, G Guelpa, A Bisetti, R Rizzoli, A Jung, S Rosini, ... Bone 9 (3), 123-130, 1988 | 131 | 1988 |
| A review of age-related dehydroepiandrosterone decline and its association with well-known geriatric syndromes: is treatment beneficial? N Samaras, D Samaras, E Frangos, A Forster, J Philippe Rejuvenation research 16 (4), 285-294, 2013 | 122 | 2013 |
| Autonomous and self-sustained circadian oscillators displayed in human islet cells P Pulimeno, T Mannic, D Sage, L Giovannoni, P Salmon, S Lemeille, ... Diabetologia 56, 497-507, 2013 | 119 | 2013 |
