High serum levels of extracellular vesicles expressing malignancy-related markers are released in patients with various types of hematological neoplastic disorders A Caivano, I Laurenzana, L De Luca, F La Rocca, V Simeon, S Trino, ... Tumor Biology 36, 9739-9752, 2015 | 189 | 2015 |
MiRNAs and piRNAs from bone marrow mesenchymal stem cell extracellular vesicles induce cell survival and inhibit cell differentiation of cord blood hematopoietic stem cells: a … L De Luca, S Trino, I Laurenzana, V Simeon, G Calice, S Raimondo, ... Oncotarget 7 (6), 6676, 2016 | 110 | 2016 |
Lenalidomide restrains motility and overangiogenic potential of bone marrow endothelial cells in patients with active multiple myeloma A De Luisi, A Ferrucci, AML Coluccia, R Ria, M Moschetta, E de Luca, ... Clinical Cancer Research 17 (7), 1935-1946, 2011 | 88 | 2011 |
MicroRNAs as new biomarkers for diagnosis and prognosis, and as potential therapeutic targets in acute myeloid leukemia S Trino, D Lamorte, A Caivano, I Laurenzana, D Tagliaferri, G Falco, ... International journal of molecular sciences 19 (2), 460, 2018 | 86 | 2018 |
MicroRNA-155 in serum-derived extracellular vesicles as a potential biomarker for hematologic malignancies-a short report A Caivano, F La Rocca, V Simeon, M Girasole, S Dinarelli, I Laurenzana, ... Cellular Oncology 40, 97-103, 2017 | 83 | 2017 |
A HGF/cMET autocrine loop is operative in multiple myeloma bone marrow endothelial cells and may represent a novel therapeutic target A Ferrucci, M Moschetta, MA Frassanito, S Berardi, I Catacchio, R Ria, ... Clinical cancer research 20 (22), 5796-5807, 2014 | 78 | 2014 |
HIF-1α of bone marrow endothelial cells implies relapse and drug resistance in patients with multiple myeloma and may act as a therapeutic target R Ria, I Catacchio, S Berardi, A De Luisi, A Caivano, C Piccoli, V Ruggieri, ... Clinical Cancer Research 20 (4), 847-858, 2014 | 64 | 2014 |
Clinical relevance of extracellular vesicles in hematological neoplasms: from liquid biopsy to cell biopsy S Trino, D Lamorte, A Caivano, L De Luca, A Sgambato, I Laurenzana Leukemia 35 (3), 661-678, 2021 | 63 | 2021 |
Vaccination with filamentous bacteriophages targeting DEC‐205 induces DC maturation and potent anti‐tumor T‐cell responses in the absence of adjuvants R Sartorius, C Bettua, L D'Apice, A Caivano, M Trovato, D Russo, I Zanoni, ... European journal of immunology 41 (9), 2573-2584, 2011 | 63 | 2011 |
Characterization and prognostic relevance of circulating microvesicles in chronic lymphocytic leukemia L De Luca, G D’Arena, V Simeon, S Trino, I Laurenzana, A Caivano, ... Leukemia & lymphoma 58 (6), 1424-1432, 2017 | 56 | 2017 |
Mesenchymal stem cell derived extracellular vesicles: a role in hematopoietic transplantation? L De Luca, S Trino, I Laurenzana, D Lamorte, A Caivano, L Del Vecchio, ... International Journal of Molecular Sciences 18 (5), 1022, 2017 | 51 | 2017 |
Knockdown of miR-128a induces Lin28a expression and reverts myeloid differentiation blockage in acute myeloid leukemia L De Luca, S Trino, I Laurenzana, D Tagliaferri, G Falco, V Grieco, ... Cell death & disease 8 (6), e2849-e2849, 2017 | 43 | 2017 |
Extracellular vesicles: a new prospective in crosstalk between microenvironment and stem cells in hematological malignancies I Laurenzana, D Lamorte, S Trino, L De Luca, C Ambrosino, P Zoppoli, ... Stem cells international 2018 (1), 9863194, 2018 | 42 | 2018 |
Extracellular vesicles in hematological malignancies: from biology to therapy A Caivano, F La Rocca, I Laurenzana, S Trino, L De Luca, D Lamorte, ... International Journal of Molecular Sciences 18 (6), 1183, 2017 | 40 | 2017 |
Four proteins governing overangiogenic endothelial cell phenotype in patients with multiple myeloma are plausible therapeutic targets S Berardi, A Caivano, R Ria, B Nico, R Savino, R Terracciano, G De Tullio, ... Oncogene 31 (18), 2258-2269, 2012 | 40 | 2012 |
Induction of specific T-helper and cytolytic responses to epitopes displayed on a virus-like protein scaffold derived from the pyruvate dehydrogenase multienzyme complex GJ Domingo, A Caivano, R Sartorius, P Barba, M Bäckström, ... Vaccine 21 (13-14), 1502-1509, 2003 | 40 | 2003 |
Co-immunization with multimeric scaffolds and DNA rapidly induces potent autologous HIV-1 neutralizing antibodies and CD8+ T cells JP Jaworski, SJ Krebs, M Trovato, DN Kovarik, Z Brower, WF Sutton, ... PloS one 7 (2), e31464, 2012 | 39 | 2012 |
P53-MDM2 pathway: Evidences for a new targeted therapeutic approach in B-acute lymphoblastic leukemia S Trino, L De Luca, I Laurenzana, A Caivano, L Del Vecchio, G Martinelli, ... Frontiers in Pharmacology 7, 491, 2016 | 35 | 2016 |
Use of fusion proteins and procaryotic display systems for delivery of HIV-1 antigens: development of novel vaccines for HIV-1 infection PD Berardinis, R Sartorius, A Caivano, D Mascolo, GJ Domingo, ... Current HIV Research 1 (4), 441-446, 2003 | 32 | 2003 |
Hit Recycling: Discovery of a Potent Carbonic Anhydrase Inhibitor by in Silico Target Fishing M Mori, Y Cau, G Vignaroli, I Laurenzana, A Caivano, D Vullo, ... ACS chemical biology 10 (9), 1964-1969, 2015 | 30 | 2015 |