Overcoming the challenges of membrane protein crystallography EP Carpenter, K Beis, AD Cameron, S Iwata Current opinion in structural biology 18 (5), 581-586, 2008 | 705 | 2008 |
Structure and molecular mechanism of a nucleobase–cation–symport-1 family transporter S Weyand, T Shimamura, S Yajima, S Suzuki, O Mirza, K Krusong, ... Science 322 (5902), 709-713, 2008 | 412 | 2008 |
G-protein-coupled receptor inactivation by an allosteric inverse-agonist antibody T Hino, T Arakawa, H Iwanari, T Yurugi-Kobayashi, C Ikeda-Suno, ... Nature 482 (7384), 237-240, 2012 | 373 | 2012 |
Crystal structure of a prokaryotic homologue of the mammalian oligopeptide–proton symporters, PepT1 and PepT2 S Newstead, D Drew, AD Cameron, VLG Postis, X Xia, PW Fowler, ... The EMBO journal 30 (2), 417-426, 2011 | 339 | 2011 |
Molecular basis of alternating access membrane transport by the sodium-hydantoin transporter Mhp1 T Shimamura, S Weyand, O Beckstein, NG Rutherford, JM Hadden, ... Science 328 (5977), 470-473, 2010 | 326 | 2010 |
Crystal structure of human glyoxalase I—evidence for gene duplication and 3D domain swapping AD Cameron, B Olin, M Ridderström, B Mannervik, TA Jones The EMBO journal 16 (12), 3386-3395, 1997 | 290 | 1997 |
Crystal structure of a bacterial homologue of the bile acid sodium symporter ASBT NJ Hu, S Iwata, AD Cameron, D Drew Nature 478 (7369), 408-411, 2011 | 279 | 2011 |
A two-domain elevator mechanism for sodium/proton antiport C Lee, HJ Kang, C von Ballmoos, S Newstead, P Uzdavinys, DL Dotson, ... Nature 501 (7468), 573-577, 2013 | 259 | 2013 |
Alternating access mechanism in the POT family of oligopeptide transporters N Solcan, J Kwok, PW Fowler, AD Cameron, D Drew, S Iwata, ... The EMBO journal 31 (16), 3411-3421, 2012 | 250 | 2012 |
Crystal structure of the anion exchanger domain of human erythrocyte band 3 T Arakawa, T Kobayashi-Yurugi, Y Alguel, H Iwanari, H Hatae, M Iwata, ... Science 350 (6261), 680-684, 2015 | 249 | 2015 |
Clustering procedures for the optimal selection of data sets from multiple crystals in macromolecular crystallography J Foadi, P Aller, Y Alguel, A Cameron, D Axford, RL Owen, W Armour, ... Acta Crystallographica Section D: Biological Crystallography 69 (8), 1617-1632, 2013 | 245 | 2013 |
1, 4, 5, 6-tetrahydropyrrolo [3, 4-c] pyrazoles: identification of a potent Aurora kinase inhibitor with a favorable antitumor kinase inhibition profile D Fancelli, J Moll, M Varasi, R Bravo, R Artico, D Berta, S Bindi, ... Journal of medicinal chemistry 49 (24), 7247-7251, 2006 | 244 | 2006 |
Crystal structure of human glyoxalase II and its complex with a glutathione thiolester substrate analogue AD Cameron, M Ridderström, B Olin, B Mannervik Structure 7 (9), 1067-1078, 1999 | 243 | 1999 |
Structure of Escherichia coli ribokinase in complex with ribose and dinucleotide determined to 1.8 Å resolution: insights into a new family of kinase structures JA Sigrell, AD Cameron, TA Jones, SL Mowbray Structure 6 (2), 183-193, 1998 | 225 | 1998 |
Structural analysis of human alpha-class glutathione transferase A1-1 in the apo-form and in complexes with ethacrynic acid and its glutathione conjugate AD Cameron, I Sinning, G L'Hermite, B Olin, PG Board, B Mannervik, ... Structure 3 (7), 717-727, 1995 | 213 | 1995 |
3-Aminopyrazole inhibitors of CDK2/cyclin A as antitumor agents. 1. Lead finding P Pevarello, MG Brasca, R Amici, P Orsini, G Traquandi, L Corti, C Piutti, ... Journal of medicinal chemistry 47 (13), 3367-3380, 2004 | 182 | 2004 |
Benchmarking membrane protein detergent stability for improving throughput of high-resolution X-ray structures Y Sonoda, S Newstead, NJ Hu, Y Alguel, E Nji, K Beis, S Yashiro, C Lee, ... Structure 19 (1), 17-25, 2011 | 179 | 2011 |
Crystal structure of glucansucrase from the dental caries pathogen Streptococcus mutans K Ito, S Ito, T Shimamura, S Weyand, Y Kawarasaki, T Misaka, K Abe, ... Journal of molecular biology 408 (2), 177-186, 2011 | 175 | 2011 |
Potent and selective Aurora inhibitors identified by the expansion of a novel scaffold for protein kinase inhibition D Fancelli, D Berta, S Bindi, A Cameron, P Cappella, P Carpinelli, ... Journal of medicinal chemistry 48 (8), 3080-3084, 2005 | 174 | 2005 |
Reaction mechanism of glyoxalase I explored by an X-ray crystallographic analysis of the human enzyme in complex with a transition state analogue AD Cameron, M Ridderström, B Olin, MJ Kavarana, DJ Creighton, ... Biochemistry 38 (41), 13480-13490, 1999 | 171 | 1999 |