Genomic classification of cutaneous melanoma R Akbani, KC Akdemir, B áArman Aksoy, M Albert, A Ally, SB Amin, ... Cell 161 (7), 1681-1696, 2015 | 2695 | 2015 |
Oncogenic signaling pathways in the cancer genome atlas F Sanchez-Vega, M Mina, J Armenia, WK Chatila, A Luna, KC La, ... Cell 173 (2), 321-337. e10, 2018 | 2501 | 2018 |
Loss of PTEN promotes resistance to T cell–mediated immunotherapy W Peng, JQ Chen, C Liu, S Malu, C Creasy, MT Tetzlaff, C Xu, ... Cancer discovery 6 (2), 202-216, 2016 | 1393 | 2016 |
Analysis of immune signatures in longitudinal tumor samples yields insight into biomarkers of response and mechanisms of resistance to immune checkpoint blockade PL Chen, W Roh, A Reuben, ZA Cooper, CN Spencer, PA Prieto, JP Miller, ... Cancer discovery 6 (8), 827-837, 2016 | 940 | 2016 |
Integrative genomic analysis of cholangiocarcinoma identifies distinct IDH-mutant molecular profiles F Farshidfar, S Zheng, MC Gingras, Y Newton, J Shih, AG Robertson, ... Cell reports 18 (11), 2780-2794, 2017 | 643 | 2017 |
Oncogenic NRAS signaling differentially regulates survival and proliferation in melanoma LN Kwong, JC Costello, H Liu, S Jiang, TL Helms, AE Langsdorf, ... Nature medicine 18 (10), 1503-1510, 2012 | 386 | 2012 |
Passenger deletions generate therapeutic vulnerabilities in cancer FL Muller, S Colla, E Aquilanti, VE Manzo, G Genovese, J Lee, ... Nature 488 (7411), 337-342, 2012 | 364 | 2012 |
APC and Its Modifiers in Colon Cancer LN Kwong, WF Dove Apc Proteins, 85-106, 2009 | 335 | 2009 |
Integrative genome comparison of primary and metastatic melanomas O Kabbarah, C Nogueira, B Feng, RM Nazarian, M Bosenberg, M Wu, ... PloS one 5 (5), e10770, 2010 | 258 | 2010 |
Systematic identification of signaling pathways with potential to confer anticancer drug resistance CA Martz, KA Ottina, KR Singleton, JS Jasper, SE Wardell, ... Science signaling 7 (357), ra121-ra121, 2014 | 225 | 2014 |
Non-germline genetically engineered mouse models for translational cancer research J Heyer, LN Kwong, SW Lowe, L Chin Nature Reviews Cancer 10 (7), 470-480, 2010 | 206 | 2010 |
Oncogenic Kras drives invasion and maintains metastases in colorectal cancer AT Boutin, WT Liao, M Wang, SS Hwang, TV Karpinets, H Cheung, ... Genes & development 31 (4), 370-382, 2017 | 199 | 2017 |
A target-selected Apc-mutant rat kindred enhances the modeling of familial human colon cancer JM Amos-Landgraf, LN Kwong, CM Kendziorski, M Reichelderfer, ... Proceedings of the National Academy of Sciences 104 (10), 4036-4041, 2007 | 184 | 2007 |
A pan-cancer analysis reveals high-frequency genetic alterations in mediators of signaling by the TGF-β superfamily A Korkut, S Zaidi, RS Kanchi, S Rao, NR Gough, A Schultz, X Li, ... Cell systems 7 (4), 422-437. e7, 2018 | 145 | 2018 |
Efficacy of the combination of MEK and CDK4/6 inhibitors in vitro and in vivo in KRAS mutant colorectal cancer models MS Lee, TL Helms, N Feng, J Gay, QE Chang, F Tian, JY Wu, C Toniatti, ... Oncotarget 7 (26), 39595, 2016 | 129 | 2016 |
Co-clinical assessment identifies patterns of BRAF inhibitor resistance in melanoma LN Kwong, GM Boland, DT Frederick, TL Helms, AT Akid, JP Miller, ... The Journal of clinical investigation 125 (4), 1459-1470, 2015 | 124 | 2015 |
microRNA regulatory network inference identifies miR-34a as a novel regulator of TGF-β signaling in glioblastoma G Genovese, A Ergun, SA Shukla, B Campos, J Hanna, P Ghosh, ... Cancer discovery 2 (8), 736-749, 2012 | 124 | 2012 |
Synthetic vulnerabilities of mesenchymal subpopulations in pancreatic cancer G Genovese, A Carugo, J Tepper, FS Robinson, L Li, M Svelto, L Nezi, ... Nature 542 (7641), 362-366, 2017 | 122 | 2017 |
Navigating the therapeutic complexity of PI3K pathway inhibition in melanoma LN Kwong, MA Davies Clinical cancer research 19 (19), 5310-5319, 2013 | 113 | 2013 |
Genomic profiling of biliary tract cancers and implications for clinical practice A Jain, LN Kwong, M Javle Current treatment options in oncology 17, 1-13, 2016 | 112 | 2016 |