Mammalian cysteine metabolism: new insights into regulation of cysteine metabolism MH Stipanuk, JE Dominy Jr, JI Lee, RM Coloso The Journal of nutrition 136 (6), 1652S-1659S, 2006 | 572 | 2006 |
The cAMP/PKA pathway rapidly activates SIRT1 to promote fatty acid oxidation independently of changes in NAD+ Z Gerhart-Hines, JE Dominy, SM Blättler, MP Jedrychowski, AS Banks, ... Molecular cell 44 (6), 851-863, 2011 | 367 | 2011 |
The deacetylase Sirt6 activates the acetyltransferase GCN5 and suppresses hepatic gluconeogenesis JE Dominy, Y Lee, MP Jedrychowski, H Chim, MJ Jurczak, JP Camporez, ... Molecular cell 48 (6), 900-913, 2012 | 311 | 2012 |
Mitochondrial biogenesis through activation of nuclear signaling proteins JE Dominy, P Puigserver Cold Spring Harbor perspectives in biology 5 (7), a015008, 2013 | 286 | 2013 |
The sirtuin family’s role in aging and age-associated pathologies JA Hall, JE Dominy, Y Lee, P Puigserver The Journal of clinical investigation 123 (3), 973-979, 2013 | 276 | 2013 |
Cyclin D1–Cdk4 controls glucose metabolism independently of cell cycle progression Y Lee, JE Dominy, YJ Choi, M Jurczak, N Tolliday, JP Camporez, H Chim, ... Nature 510 (7506), 547-551, 2014 | 249 | 2014 |
Oleic acid stimulates complete oxidation of fatty acids through protein kinase A-dependent activation of SIRT1-PGC1α complex JH Lim, Z Gerhart-Hines, JE Dominy, Y Lee, S Kim, M Tabata, YK Xiang, ... Journal of Biological Chemistry 288 (10), 7117-7126, 2013 | 241 | 2013 |
Cysteine dioxygenase: a robust system for regulation of cellular cysteine levels MH Stipanuk, I Ueki, JE Dominy, CR Simmons, LL Hirschberger Amino acids 37, 55-63, 2009 | 240 | 2009 |
The cytoprotective role of taurine in exercise-induced muscle injury R Dawson, Jr, M Biasetti, S Messina, J Dominy Amino acids 22 (4), 309-324, 2002 | 224 | 2002 |
Nutrient-dependent regulation of PGC-1α's acetylation state and metabolic function through the enzymatic activities of Sirt1/GCN5 JE Dominy Jr, Y Lee, Z Gerhart-Hines, P Puigserver Biochimica et biophysica acta (BBA)-proteins and proteomics 1804 (8), 1676-1683, 2010 | 223 | 2010 |
Discovery and characterization of a second mammalian thiol dioxygenase, cysteamine dioxygenase JE Dominy, CR Simmons, LL Hirschberger, J Hwang, RM Coloso, ... Journal of Biological Chemistry 282 (35), 25189-25198, 2007 | 187 | 2007 |
Selective chemical inhibition of PGC-1α gluconeogenic activity ameliorates type 2 diabetes K Sharabi, H Lin, CDJ Tavares, JE Dominy, JP Camporez, RJ Perry, ... Cell 169 (1), 148-160. e15, 2017 | 180 | 2017 |
Synthesis of amino acid cofactor in cysteine dioxygenase is regulated by substrate and represents a novel post-translational regulation of activity JE Dominy, J Hwang, S Guo, LL Hirschberger, S Zhang, MH Stipanuk Journal of Biological Chemistry 283 (18), 12188-12201, 2008 | 145 | 2008 |
Thiol dioxygenases: unique families of cupin proteins MH Stipanuk, CR Simmons, P Andrew Karplus, JE Dominy Amino acids 41, 91-102, 2011 | 128 | 2011 |
Identification and characterization of bacterial cysteine dioxygenases: a new route of cysteine degradation for eubacteria JE Dominy Jr, CR Simmons, PA Karplus, AM Gehring, MH Stipanuk Journal of bacteriology 188 (15), 5561-5569, 2006 | 126 | 2006 |
New Roles for Cysteine and Transsulfuration Enzymes: Production of H2S, a Neuromodulator and Smooth Muscle Relaxant JE Dominy, MH Stipanuk Nutrition reviews 62 (9), 348-353, 2004 | 123 | 2004 |
HepG2/C3A cells respond to cysteine deprivation by induction of the amino acid deprivation/integrated stress response pathway JI Lee, JE Dominy Jr, AK Sikalidis, LL Hirschberger, W Wang, ... Physiological genomics 33 (2), 218-229, 2008 | 119 | 2008 |
Genetic inhibition of hepatic acetyl-CoA carboxylase activity increases liver fat and alters global protein acetylation JDY Chow, RT Lawrence, ME Healy, JE Dominy, JA Liao, DS Breen, ... Molecular metabolism 3 (4), 419-431, 2014 | 118 | 2014 |
A Putative Fe2+-Bound Persulfenate Intermediate in Cysteine Dioxygenase CR Simmons, K Krishnamoorthy, SL Granett, DJ Schuller, JE Dominy Jr, ... Biochemistry 47 (44), 11390-11392, 2008 | 99 | 2008 |
Regulation of cysteine dioxygenase degradation is mediated by intracellular cysteine levels and the ubiquitin–26 S proteasome system in the living rat JE Dominy Jr, LL Hirschberger, RM Coloso, MH Stipanuk Biochemical Journal 394 (1), 267-273, 2006 | 99 | 2006 |