Bile acids permeabilize the blood brain barrier after bile duct ligation in rats via Rac1-dependent mechanisms M Quinn, M McMillin, C Galindo, G Frampton, HY Pae, S DeMorrow Digestive and Liver Disease 46 (6), 527-534, 2014 | 222 | 2014 |
Effects of bile acids on neurological function and disease M McMillin, S DeMorrow The FASEB Journal 30 (11), 3658, 2016 | 157 | 2016 |
Interleukin-6-driven progranulin expression increases cholangiocarcinoma growth by an Akt-dependent mechanism G Frampton, P Invernizzi, F Bernuzzi, HY Pae, M Quinn, D Horvat, ... Gut 61 (2), 268-277, 2012 | 133 | 2012 |
TGR 5 signaling reduces neuroinflammation during hepatic encephalopathy M McMillin, G Frampton, R Tobin, G Dusio, J Smith, H Shin, ... Journal of neurochemistry 135 (3), 565-576, 2015 | 110 | 2015 |
Bile acid signaling is involved in the neurological decline in a murine model of acute liver failure M McMillin, G Frampton, M Quinn, S Ashfaq, S Grant, S DeMorrow The American Journal of Pathology 186 (2), 312-323, 2016 | 109 | 2016 |
TGFβ1 exacerbates blood–brain barrier permeability in a mouse model of hepatic encephalopathy via upregulation of MMP9 and downregulation of claudin-5 MA McMillin, GA Frampton, AP Seiwell, NS Patel, AN Jacobs, ... Laboratory investigation 95 (8), 903-913, 2015 | 105 | 2015 |
Cholangiocarcinoma pathogenesis: Role of the tumor microenvironment D Leyva-Illades, M McMillin, M Quinn, S DeMorrow Translational gastrointestinal cancer 1 (1), 71, 2012 | 90 | 2012 |
Role of TGR5 (GPBAR1) in liver disease V Keitel, D Häussinger Seminars in liver disease 38 (04), 333-339, 2018 | 89 | 2018 |
Bile acid-mediated sphingosine-1-phosphate receptor 2 signaling promotes neuroinflammation during hepatic encephalopathy in mice M McMillin, G Frampton, S Grant, S Khan, J Diocares, A Petrescu, A Wyatt, ... Frontiers in Cellular Neuroscience 11, 191, 2017 | 84 | 2017 |
Suppression of the HPA axis during cholestasis can be attributed to hypothalamic bile acid signaling M McMillin, G Frampton, M Quinn, A Divan, S Grant, N Patel, ... Molecular Endocrinology 29 (12), 1720-1730, 2015 | 82 | 2015 |
Neuronal CCL2 is upregulated during hepatic encephalopathy and contributes to microglia activation and neurological decline M McMillin, G Frampton, M Thompson, C Galindo, H Standeford, ... Journal of neuroinflammation 11, 1-11, 2014 | 76 | 2014 |
Monoamine oxidase A expression is suppressed in human cholangiocarcinoma via coordinated epigenetic and IL-6-driven events L Huang, G Frampton, A Rao, K Zhang, W Chen, J Lai, X Yin, K Walker, ... Laboratory investigation 92 (10), 1451-1460, 2012 | 62 | 2012 |
The direct contribution of astrocytes and microglia to the pathogenesis of hepatic encephalopathy V Jaeger, S DeMorrow, M McMillin Journal of clinical and translational hepatology 7 (4), 352, 2019 | 55 | 2019 |
Hepatic alterations are accompanied by changes to bile acid transporter-expressing neurons in the hypothalamus after traumatic brain injury D Nizamutdinov, S DeMorrow, M McMillin, J Kain, S Mukherjee, ... Scientific Reports 7 (1), 40112, 2017 | 42 | 2017 |
Direct comparison of the thioacetamide and azoxymethane models of type A hepatic encephalopathy in mice S Grant, M McMillin, G Frampton, AD Petrescu, E Williams, V Jaeger, ... Gene expression 18 (3), 171, 2018 | 39 | 2018 |
FXR-mediated cortical cholesterol accumulation contributes to the pathogenesis of type A hepatic encephalopathy M McMillin, S Grant, G Frampton, AD Petrescu, J Kain, E Williams, ... Cellular and Molecular Gastroenterology and Hepatology 6 (1), 47-63, 2018 | 39 | 2018 |
Suppression of the HPA axis during extrahepatic biliary obstruction induces cholangiocyte proliferation in the rat M Quinn, Y Ueno, HY Pae, L Huang, G Frampton, C Galindo, H Francis, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 302 (1 …, 2012 | 38 | 2012 |
Tumor microenvironment alters chemoresistance of hepatocellular carcinoma through CYP3A4 metabolic activity A Özkan, DL Stolley, ENK Cressman, M McMillin, S DeMorrow, ... Frontiers in oncology 11, 662135, 2021 | 34 | 2021 |
Fractalkine suppression during hepatic encephalopathy promotes neuroinflammation in mice M McMillin, S Grant, G Frampton, S Andry, A Brown, S DeMorrow Journal of Neuroinflammation 13, 1-12, 2016 | 32 | 2016 |
Gli1 activation and protection against hepatic encephalopathy is suppressed by circulating transforming growth factor β1 in mice M McMillin, C Galindo, HY Pae, G Frampton, PL Di Patre, M Quinn, ... Journal of hepatology 61 (6), 1260-1266, 2014 | 32 | 2014 |