| Pancreatic cancer is marked by complement-high blood monocytes and tumor-associated macrophages SB Kemp, NG Steele, ES Carpenter, KL Donahue, GG Bushnell, ... Life science alliance 4 (6), 2021 | 86 | 2021 |
| Metastatic conditioning of myeloid cells at a subcutaneous synthetic niche reflects disease progression and predicts therapeutic outcomes RS Oakes, GG Bushnell, SM Orbach, P Kandagatla, Y Zhang, AH Morris, ... Cancer research 80 (3), 602-612, 2020 | 41 | 2020 |
| The design of antimicrobial LL37-modified collagen-hyaluronic acid detachable multilayers ME Cassin, AJ Ford, SM Orbach, SE Saverot, P Rajagopalan Acta biomaterialia 40, 119-129, 2016 | 36 | 2016 |
| In vitro intestinal and liver models for toxicity testing SM Orbach, RR Less, A Kothari, P Rajagopalan ACS Biomaterials Science & Engineering 3 (9), 1898-1910, 2017 | 31 | 2017 |
| Investigating acetaminophen hepatotoxicity in multi-cellular organotypic liver models SM Orbach, ME Cassin, MF Ehrich, P Rajagopalan Toxicology in Vitro 42, 10-20, 2017 | 29 | 2017 |
| Fibroblasts stimulate macrophage migration in interconnected extracellular matrices through tunnel formation and fiber alignment AJ Ford, SM Orbach, P Rajagopalan Biomaterials 209, 88-102, 2019 | 28 | 2019 |
| Engineered niches to analyze mechanisms of metastasis and guide precision medicine AH Morris, SM Orbach, GG Bushnell, RS Oakes, JS Jeruss, LD Shea Cancer research 80 (18), 3786-3794, 2020 | 26 | 2020 |
| Cargo-free immunomodulatory nanoparticles combined with anti-PD-1 antibody for treating metastatic breast cancer Y Zhang, KR Hughes, RM Raghani, J Ma, S Orbach, JS Jeruss, LD Shea Biomaterials 269, 120666, 2021 | 25 | 2021 |
| A synthetic metastatic niche reveals antitumor neutrophils drive breast cancer metastatic dormancy in the lungs J Wang, R Ocadiz-Ruiz, MS Hall, GG Bushnell, SM Orbach, JT Decker, ... Nature communications 14 (1), 4790, 2023 | 15 | 2023 |
| High-throughput toxicity testing of chemicals and mixtures in organotypic multi-cellular cultures of primary human hepatic cells SM Orbach, MF Ehrich, P Rajagopalan Toxicology in Vitro 51, 83-94, 2018 | 15 | 2018 |
| Multi-cellular transitional organotypic models to investigate liver fibrosis SM Orbach, AJ Ford, SE Saverot, P Rajagopalan Acta Biomaterialia 82, 79-92, 2018 | 13 | 2018 |
| Single-cell RNA-sequencing identifies anti-cancer immune phenotypes in the early lung metastatic niche during breast cancer SM Orbach, MD Brooks, Y Zhang, SE Campit, GG Bushnell, JT Decker, ... Clinical & experimental metastasis 39 (6), 865-881, 2022 | 10 | 2022 |
| Biodegradable nanoparticles induce cGAS/STING-dependent reprogramming of myeloid cells to promote tumor immunotherapy JR Podojil, AC Cogswell, MY Chiang, V Eaton, I Ifergan, T Neef, D Xu, ... Frontiers in immunology 13, 887649, 2022 | 10 | 2022 |
| Disease-induced immunomodulation at biomaterial scaffolds detects early pancreatic cancer in a spontaneous model GG Bushnell, SM Orbach, JA Ma, HC Crawford, MS Wicha, JS Jeruss, ... Biomaterials 269, 120632, 2021 | 9 | 2021 |
| The hepatocyte proteome in organotypic rat liver models and the influence of the local microenvironment LT Vu, SM Orbach, WK Ray, ME Cassin, P Rajagopalan, RF Helm Proteome Science 15, 1-15, 2016 | 6 | 2016 |
| An engineered niche delineates metastatic potential of breast cancer SM Orbach, CY DeVaull, EJ Bealer, BC Ross, JS Jeruss, LD Shea Bioengineering & Translational Medicine 9 (1), e10606, 2024 | 5 | 2024 |
| Myeloid cell reprogramming alleviates immunosuppression and promotes clearance of metastatic lesions RM Raghani, JA Ma, Y Zhang, SM Orbach, J Wang, M Zeinali, S Nagrath, ... Frontiers in Oncology 12, 1039993, 2022 | 3 | 2022 |
| Computational Construction of Toxicant Signaling Networks JN Law, SM Orbach, BR Weston, PA Steele, P Rajagopalan, TM Murali Chemical Research in Toxicology 36 (8), 1267-1277, 2023 | 1 | 2023 |
| Dynamic Transcriptional Programs During Single NK Cell Killing: Connecting Form to Function in Cellular Immunotherapy JT Decker, MS Hall, D Nanua, SM Orbach, J Roy, A Angadi, J Caton, ... Cellular and Molecular Bioengineering 17 (3), 177-188, 2024 | | 2024 |
| Cargo-free scaffold implant recruits metastatic cancer cells via lung-mimicking myeloid cell S100A8/A9 axis J Wang, MS Hall, GG Bushnell, SM Orbach, RM Raghani, Y Zhang, ... bioRxiv, 789974, 2019 | | 2019 |
