Th17 cells contribute to combination MEK inhibitor and anti-PD-L1 therapy resistance in KRAS/p53 mutant lung cancers DH Peng, BL Rodriguez, L Diao, PO Gaudreau, A Padhye, JM Konen, ... Nature communications 12 (1), 2606, 2021 | 63 | 2021 |
Sox2 Regulates the Emergence of Lung Basal Cells by Directly Activating the Transcription of Trp63 JK Ochieng, K Schilders, H Kool, A Boerema-De Munck, ... American journal of respiratory cell and molecular biology 51 (2), 311-322, 2014 | 60 | 2014 |
Hypoxia inducible factor 3α plays a critical role in alveolarization and distal epithelial cell differentiation during mouse lung development Y Huang, J Kapere Ochieng, MB Kempen, AB Munck, S Swagemakers, ... PLoS One 8 (2), e57695, 2013 | 40 | 2013 |
Augmented Lipocalin-2 is Associated with COPD and Counteracts Lung Adenocarcinoma Development Am J Respir Crit Care Med, 2020 | 29* | 2020 |
Development of Kras mutant lung adenocarcinoma in mice with knockout of the airway lineage‐specific gene Gprc5a J Fujimoto, S Nunomura‐Nakamura, Y Liu, W Lang, T McDowell, ... International journal of cancer 141 (8), 1589-1599, 2017 | 29 | 2017 |
Dual inhibition of MEK and AXL targets tumor cell heterogeneity and prevents resistant outgrowth mediated by the epithelial-to-mesenchymal transition in NSCLC JM Konen, BL Rodriguez, A Padhye, JK Ochieng, L Gibson, L Diao, ... Cancer research 81 (5), 1398-1412, 2021 | 25 | 2021 |
Next-generation immunotherapies to improve anticancer immunity Y Shi, K Tomczak, J Li, JK Ochieng, Y Lee, C Haymaker Frontiers in pharmacology 11, 566401, 2021 | 20 | 2021 |
MBIP (MAP3K12 binding inhibitory protein) drives NSCLC metastasis by JNK-dependent activation of MMPs JK Ochieng, ST Kundu, R Bajaj, B Leticia Rodriguez, JJ Fradette, ... Oncogene 39 (43), 6719-6732, 2020 | 19 | 2020 |
Differentiated type II pneumocytes can be reprogrammed by ectopic Sox2 expression J Kapere Ochieng, K Schilders, H Kool, M Buscop-van Kempen, ... PLoS One 9 (9), e107248, 2014 | 17 | 2014 |
Targeting CDK4 overcomes EMT-mediated tumor heterogeneity and therapeutic resistance in KRAS-mutant lung cancer A Padhye, JM Konen, BL Rodriguez, JJ Fradette, JK Ochieng, L Diao, ... JCI insight 6 (17), 2021 | 16 | 2021 |
Targeting immunosuppressive Ly6C+ classical monocytes reverses anti-PD-1/CTLA-4 immunotherapy resistance BL Rodriguez, L Chen, Y Li, S Miao, DH Peng, JJ Fradette, L Diao, ... Frontiers in immunology 14, 1161869, 2023 | 6 | 2023 |
Cabozantinib monotherapy for advanced adrenocortical carcinoma: a single-arm, phase 2 trial MT Campbell, V Balderrama-Brondani, C Jimenez, G Tamsen, LP Marcal, ... The Lancet Oncology 25 (5), 649-657, 2024 | 5 | 2024 |
Host lipocalin 2 protects against Kras mutant lung cancer development by maintaining an anti-tumor immune contexture M Hassane, W Treekitkarnmongkol, TL McDowell, S Sivakumar, W Lang, ... Cancer Research 79 (13_Supplement), 4952-4952, 2019 | 1 | 2019 |
Role of SOX2 in foregut development in relation to congenital abnormalities K Schilders, JK Ochieng, CP van de Ven, C Gontan, D Tibboel, RJ Rottier World Journal of Medical Genetics 4 (4), 94-104, 2014 | 1 | 2014 |
Changes in circulating immune biomarkers following nivolumab with or without ipilimumab for metastatic anal cancer (NCI9673). VK Morris, J Ochieng, KK Ciombor, BN Polite, S Mukherjee, JC Krauss, ... Journal of Clinical Oncology 42 (3_suppl), 3-3, 2024 | | 2024 |
Targeting immunosuppressive classical monocytes prevents immunotherapy resistance BL Rodriguez, L Chen, Y Li, S Miao, DH Peng, J Fradette, L Diao, ... | | 2022 |
MBIP promotes cell motility and metastasis in Kras/p53 mutant non-small cell lung cancer JK Ochieng 8th Annual Postdoctoral Science Symposium, 51, 2018 | | 2018 |
Development of Kras mutant lung adenocarcinoma in tobacco carcinogen exposed mice with knockout of the airway lineage-specific G-protein coupled receptor Gprc5a J Fujimoto, S Nunomura, W Lang, Y Liu, J Wei, J Ochieng, Y Jakubek, ... Cancer Research 76 (14_Supplement), 4056-4056, 2016 | | 2016 |
Identifying Sox2 interaction partners in the developing lung K Schilders | | 2016 |
Expression of the lipocalin 2 oncogene in the development of smoking-associated and Kras mutant lung adenocarcinoma JFHK Joshua Ochieng, Sayuri Nunomura, Wenhua Lang, Jinsong Wei, Li Xu ... 107th AACR 76 (14), 1124, 2016 | | 2016 |