Early correlation of microglial activation with enhanced tumor necrosis factor-alpha and monocyte chemoattractant protein-1 expression specifically within the entorhinal cortex … MC Janelsins, MA Mastrangelo, S Oddo, FM LaFerla, HJ Federoff, ... Journal of neuroinflammation 2 (1), 1-12, 2005 | 319 | 2005 |
Detailed immunohistochemical characterization of temporal and spatial progression of Alzheimer's disease-related pathologies in male triple-transgenic mice MA Mastrangelo, WJ Bowers BMC neuroscience 9, 1-31, 2008 | 290 | 2008 |
Triple‐transgenic Alzheimer's disease mice exhibit region‐specific abnormalities in brain myelination patterns prior to appearance of amyloid and tau pathology MK Desai, KL Sudol, MC Janelsins, MA Mastrangelo, ME Frazer, ... Glia 57 (1), 54-65, 2009 | 279 | 2009 |
Chronic neuron-specific tumor necrosis factor-alpha expression enhances the local inflammatory environment ultimately leading to neuronal death in 3xTg-AD mice MC Janelsins, MA Mastrangelo, KM Park, KL Sudol, WC Narrow, S Oddo, ... The American journal of pathology 173 (6), 1768-1782, 2008 | 262 | 2008 |
Early oligodendrocyte/myelin pathology in Alzheimer's disease mice constitutes a novel therapeutic target MK Desai, MA Mastrangelo, DA Ryan, KL Sudol, WC Narrow, WJ Bowers The American journal of pathology 177 (3), 1422-1435, 2010 | 242 | 2010 |
Genome-wide association transethnic meta-analyses identifies novel associations regulating coagulation factor VIII and von Willebrand factor plasma levels M Sabater-Lleal, JE Huffman, PS De Vries, J Marten, MA Mastrangelo, ... Circulation 139 (5), 620-635, 2019 | 130 | 2019 |
Ablation of TNF-RI/RII expression in Alzheimer's disease mice leads to an unexpected enhancement of pathology: implications for chronic pan-TNF-α suppressive therapeutic … SL Montgomery, MA Mastrangelo, D Habib, WC Narrow, SA Knowlden, ... The American journal of pathology 179 (4), 2053-2070, 2011 | 130 | 2011 |
Interferon-γ differentially affects Alzheimer’s disease pathologies and induces neurogenesis in triple transgenic-AD mice MA Mastrangelo, KL Sudol, WC Narrow, WJ Bowers The American journal of pathology 175 (5), 2076-2088, 2009 | 110 | 2009 |
SIRT6 protects against endothelial dysfunction and atherosclerosis in mice S Xu, M Yin, M Koroleva, MA Mastrangelo, W Zhang, P Bai, PJ Little, ... Aging (Albany NY) 8 (5), 1064, 2016 | 105 | 2016 |
Aβ-directed single-chain antibody delivery via a serotype-1 AAV vector improves learning behavior and pathology in Alzheimer's disease mice DA Ryan, MA Mastrangelo, WC Narrow, MA Sullivan, HJ Federoff, ... Molecular Therapy 18 (8), 1471-1481, 2010 | 84 | 2010 |
Helper-free HSV-1 amplicons elicit a markedly less robust innate immune response in the CNS JA Olschowka, WJ Bowers, SD Hurley, MA Mastrangelo, HJ Federoff Molecular Therapy 7 (2), 218-227, 2003 | 80 | 2003 |
Reduced pathology and improved behavioral performance in Alzheimer's disease mice vaccinated with HSV amplicons expressing amyloid-β and interleukin-4 ME Frazer, JE Hughes, MA Mastrangelo, JL Tibbens, HJ Federoff, ... Molecular Therapy 16 (5), 845-853, 2008 | 73 | 2008 |
Chronic neuron-and age-selective down-regulation of TNF receptor expression in triple-transgenic Alzheimer disease mice leads to significant modulation of amyloid-and Tau … SL Montgomery, WC Narrow, MA Mastrangelo, JA Olschowka, ... The American journal of pathology 182 (6), 2285-2297, 2013 | 68 | 2013 |
A novel TRPV4-specific agonist inhibits monocyte adhesion and atherosclerosis S Xu, B Liu, M Yin, M Koroleva, M Mastrangelo, S Ture, CN Morrell, ... Oncotarget 7 (25), 37622, 2016 | 65 | 2016 |
Neuronal precursor-restricted transduction via in utero CNS gene delivery of a novel bipartite HSV amplicon/transposase hybrid vector WJ Bowers, MA Mastrangelo, DF Howard, HA Southerland, ... Molecular Therapy 13 (3), 580-588, 2006 | 65 | 2006 |
The choline transporter Slc44a2 controls platelet activation and thrombosis by regulating mitochondrial function JA Bennett, MA Mastrangelo, SK Ture, CO Smith, SG Loelius, RA Berg, ... Nature Communications 11 (1), 3479, 2020 | 63 | 2020 |
Interleukin-17 limits hypoxia-inducible factor 1α and development of hypoxic granulomas during tuberculosis R Domingo-Gonzalez, S Das, KL Griffiths, M Ahmed, M Bambouskova, ... JCI insight 2 (19), 2017 | 61 | 2017 |
Generating differentially targeted amyloid-β specific intrabodies as a passive vaccination strategy for Alzheimer's disease KL Sudol, MA Mastrangelo, WC Narrow, ME Frazer, YR Levites, TE Golde, ... Molecular Therapy 17 (12), 2031-2040, 2009 | 57 | 2009 |
HSV amplicon-mediated Aβ vaccination in Tg2576 mice: differential antigen-specific immune responses WJ Bowers, MA Mastrangelo, HA Stanley, AE Casey, LJ Milo Jr, ... Neurobiology of aging 26 (4), 393-407, 2005 | 53 | 2005 |
Behavioral pharmacology of AR-A000002, a novel, selective 5-hydroxytryptamine1B antagonist TJ Hudzik, M Yanek, T Porrey, J Evenden, C Paronis, M Mastrangelo, ... Journal of Pharmacology and Experimental Therapeutics 304 (3), 1072-1084, 2003 | 52 | 2003 |