| Crystal structure of the catalytic domains of adenylyl cyclase in a complex with Gsα· GTPγS JJG Tesmer, RK Sunahara, AG Gilman, SR Sprang Science 278 (5345), 1907-1916, 1997 | 1028 | 1997 |
| Structure of RGS4 bound to AlF4−-activated Giα1: stabilization of the transition state for GTP hydrolysis JJG Tesmer, DM Berman, AG Gilman, SR Sprang Cell 89 (2), 251-261, 1997 | 1014 | 1997 |
| G protein-coupled receptor kinases: more than just kinases and not only for GPCRs EV Gurevich, JJG Tesmer, A Mushegian, VV Gurevich Pharmacology & therapeutics 133 (1), 40-69, 2012 | 513 | 2012 |
| Keeping G proteins at bay: A complex between G protein-coupled receptor kinase 2 and Gßγ DT Lodowski, JA Pitcher, WD Capel, RJ Lefkowitz, JJG Tesmer Science 300 (5623), 1256-1262, 2003 | 472 | 2003 |
| Crystal structure of the adenylyl cyclase activator Gsα RK Sunahara, JJG Tesmer, AG Gilman, SR Sprang Science 278 (5345), 1943-1947, 1997 | 409 | 1997 |
| Two-metal-ion catalysis in adenylyl cyclase JJG Tesmer, RK Sunahara, RA Johnson, G Gosselin, AG Gilman, ... Science 285 (5428), 756-760, 1999 | 394 | 1999 |
| Snapshot of Activated G Proteins at the Membrane: The Gαq-GRK2-Gβγ Complex VM Tesmer, T Kawano, A Shankaranarayanan, T Kozasa, JJG Tesmer Science 310 (5754), 1686-1690, 2005 | 362 | 2005 |
| The crystal structure of GMP synthetase reveals a novel catalytic triad and is a structural paradigm for two enzyme families JJG Tesmer, TJ Klem, ML Deras, VJ Davisson, JL Smith Nature structural biology 3 (1), 74-86, 1996 | 295 | 1996 |
| Exchange of substrate and inhibitor specificities between adenylyl and guanylyl cyclases RK Sunahara, A Beuve, JJG Tesmer, SR Sprang, DL Garbers, AG Gilman Journal of Biological Chemistry 273 (26), 16332-16338, 1998 | 285 | 1998 |
| Structure of Gαq-p63RhoGEF-RhoA complex reveals a pathway for the activation of RhoA by GPCRs S Lutz, A Shankaranarayanan, C Coco, M Ridilla, MR Nance, C Vettel, ... Science 318 (5858), 1923-1927, 2007 | 273 | 2007 |
| Monomeric rhodopsin is sufficient for normal rhodopsin kinase (GRK1) phosphorylation and arrestin-1 binding TH Bayburt, SA Vishnivetskiy, MA McLean, T Morizumi, C Huang, ... Journal of Biological Chemistry 286 (2), 1420-1428, 2011 | 242 | 2011 |
| Feedback inhibition of G protein-coupled receptor kinase 2 (GRK2) activity by extracellular signal-regulated kinases JA Pitcher, JJG Tesmer, JLR Freeman, WD Capel, WC Stone, ... Journal of Biological Chemistry 274 (49), 34531-34534, 1999 | 240 | 1999 |
| Paroxetine is a direct inhibitor of g protein-coupled receptor kinase 2 and increases myocardial contractility DM Thal, KT Homan, J Chen, EK Wu, PM Hinkle, ZM Huang, JK Chuprun, ... ACS chemical biology 7 (11), 1830-1839, 2012 | 219 | 2012 |
| Identification of a Giα binding site on type V adenylyl cyclase CW Dessauer, JJG Tesmer, SR Sprang, AG Gilman Journal of Biological Chemistry 273 (40), 25831-25839, 1998 | 197 | 1998 |
| Structure and function of heterotrimeric G protein-regulated Rho guanine nucleotide exchange factors M Aittaleb, CA Boguth, JJG Tesmer Molecular pharmacology 77 (2), 111-125, 2010 | 187 | 2010 |
| Structural determinants of RhoA binding and nucleotide exchange in leukemia-associated Rho guanine-nucleotide exchange factor R Kristelly, G Gao, JJG Tesmer Journal of Biological Chemistry 279 (45), 47352-47362, 2004 | 184 | 2004 |
| The structure, catalytic mechanism and regulation of adenylyl cyclase JJG Tesmer, SR Sprang Current opinion in structural biology 8 (6), 713-719, 1998 | 179 | 1998 |
| Paroxetine-mediated GRK2 inhibition reverses cardiac dysfunction and remodeling after myocardial infarction SM Schumacher, E Gao, W Zhu, X Chen, JK Chuprun, AM Feldman, ... Science translational medicine 7 (277), 277ra31-277ra31, 2015 | 160 | 2015 |
| Self-masking in an intact ERM-merlin protein: an active role for the central α-helical domain Q Li, MR Nance, R Kulikauskas, K Nyberg, R Fehon, PA Karplus, ... Journal of molecular biology 365 (5), 1446-1459, 2007 | 159 | 2007 |
| G protein-coupled receptor kinase 2/Gαq/11 interaction: a novel surface on a regulator of G protein signaling homology domain for binding Gα subunits R Sterne-Marr, JJG Tesmer, PW Day, RAP Stracquatanio, JAE Cilente, ... Journal of Biological Chemistry 278 (8), 6050-6058, 2003 | 151 | 2003 |
