Pathways for small molecule delivery to the central nervous system across the blood-brain barrier JL Mikitsh, AM Chacko Perspectives in medicinal chemistry 6, PMC. S13384, 2014 | 246 | 2014 |
Interleukin-11 is a therapeutic target in idiopathic pulmonary fibrosis B Ng, J Dong, G D’Agostino, S Viswanathan, AA Widjaja, WW Lim, ... Science translational medicine 11 (511), eaaw1237, 2019 | 221 | 2019 |
Reduction of nanoparticle avidity enhances the selectivity of vascular targeting and PET detection of pulmonary inflammation BJ Zern, AM Chacko, J Liu, CF Greineder, ER Blankemeyer, ... ACS nano 7 (3), 2461-2469, 2013 | 114 | 2013 |
Targeted delivery of antibody-based therapeutic and imaging agents to CNS tumors: crossing the blood–brain barrier divide AM Chacko, C Li, DA Pryma, S Brem, G Coukos, V Muzykantov Expert opinion on drug delivery 10 (7), 907-926, 2013 | 111 | 2013 |
Endothelial targeting of polymeric nanoparticles stably labeled with the PET imaging radioisotope iodine-124 EA Simone, BJ Zern, AM Chacko, JL Mikitsh, ER Blankemeyer, S Muro, ... Biomaterials 33 (21), 5406-5413, 2012 | 97 | 2012 |
Targeted nanocarriers for imaging and therapy of vascular inflammation AM Chacko, ED Hood, BJ Zern, VR Muzykantov Current opinion in colloid & interface science 16 (3), 215-227, 2011 | 97 | 2011 |
Shape-controlled synthesis of isotopic yttrium-90-labeled rare earth fluoride nanocrystals for multimodal imaging T Paik, AM Chacko, JL Mikitsh, JS Friedberg, DA Pryma, CB Murray ACS nano 9 (9), 8718-8728, 2015 | 51 | 2015 |
Vascular immunotargeting to endothelial determinant ICAM-1 enables optimal partnering of recombinant scFv-thrombomodulin fusion with endogenous cofactor CF Greineder, AM Chacko, S Zaytsev, BJ Zern, R Carnemolla, ED Hood, ... PloS one 8 (11), e80110, 2013 | 51 | 2013 |
Collaborative enhancement of antibody binding to distinct PECAM-1 epitopes modulates endothelial targeting AM Chacko, M Nayak, CF Greineder, HM DeLisser, VR Muzykantov PloS one 7 (4), e34958, 2012 | 46 | 2012 |
Plasmodium vivax binds host CD98hc (SLC3A2) to enter immature red blood cells B Malleret, A El Sahili, MZ Tay, G Carissimo, ASM Ong, W Novera, J Lin, ... Nature microbiology 6 (8), 991-999, 2021 | 38 | 2021 |
Development of 124I immuno-PET targeting tumor vascular TEM1/endosialin AM Chacko, C Li, M Nayak, JL Mikitsh, J Hu, C Hou, L Grasso, ... Journal of nuclear medicine 55 (3), 500-507, 2014 | 35 | 2014 |
SPECT Imaging of Herpes Simplex Virus Type1 Thymidine Kinase Gene Expression By [123I] FIAU1 SR Choi, ZP Zhuang, AM Chacko, PD Acton, J Tjuvajev-Gelovani, ... Academic radiology 12 (7), 798-805, 2005 | 31 | 2005 |
Radiopharmaceutical chemistry with iodine-124: a non-standard radiohalogen for positron emission tomography AM Chacko, C R Divgi Medicinal chemistry 7 (5), 395-412, 2011 | 30 | 2011 |
Granzyme B PET imaging of immune checkpoint inhibitor combinations in colon cancer phenotypes JL Goggi, YX Tan, SV Hartimath, B Jieu, YY Hwang, L Jiang, ... Molecular imaging and biology 22, 1392-1402, 2020 | 29 | 2020 |
Dual targeting of therapeutics to endothelial cells: collaborative enhancement of delivery and effect CF Greineder, JB Brenza, R Carnemolla, S Zaitsev, ED Hood, DC Pan, ... The FASEB Journal 29 (8), 3483, 2015 | 27 | 2015 |
Granzyme B PET imaging of combined chemotherapy and immune checkpoint inhibitor therapy in colon cancer JL Goggi, SV Hartimath, TY Xuan, S Khanapur, B Jieu, HX Chin, ... Molecular Imaging and Biology 23, 714-723, 2021 | 26 | 2021 |
Biodistribution and fate of core-labeled 125 I polymeric nanocarriers prepared by Flash NanoPrecipitation (FNP) C Tang, J Edelstein, JL Mikitsh, E Xiao, AH Hemphill, R Pagels, ... Journal of materials chemistry B 4 (14), 2428-2434, 2016 | 26 | 2016 |
Collaborative enhancement of endothelial targeting of nanocarriers by modulating platelet-endothelial cell adhesion molecule-1/CD31 epitope engagement AM Chacko, J Han, CF Greineder, BJ Zern, JL Mikitsh, M Nayak, D Menon, ... ACS nano 9 (7), 6785-6793, 2015 | 26 | 2015 |
Antibody-based tumor vascular theranostics targeting endosialin/TEM1 in a new mouse tumor vascular model C Li, AM Chacko, J Hu, K Hasegawa, J Swails, L Grasso, WS El-Deiry, ... Cancer biology & therapy 15 (4), 443-451, 2014 | 26 | 2014 |
18F-FDG as an inflammation biomarker for imaging dengue virus infection and treatment response AM Chacko, S Watanabe, KJ Herr, S Kalimuddin, JY Tham, J Ong, ... JCI insight 2 (9), 2017 | 24 | 2017 |