Thymic stromal lymphopoietin expression is increased in asthmatic airways and correlates with expression of Th2-attracting chemokines and disease severity S Ying, B O’Connor, J Ratoff, Q Meng, K Mallett, D Cousins, D Robinson, ... The Journal of Immunology 174 (12), 8183-8190, 2005 | 1034 | 2005 |
IL-33–dependent type 2 inflammation during rhinovirus-induced asthma exacerbations in vivo DJ Jackson, H Makrinioti, BMJ Rana, BWH Shamji, MB Trujillo-Torralbo, ... American journal of respiratory and critical care medicine 190 (12), 1373-1382, 2014 | 632 | 2014 |
Expression and cellular provenance of thymic stromal lymphopoietin and chemokines in patients with severe asthma and chronic obstructive pulmonary disease S Ying, B O'Connor, J Ratoff, Q Meng, C Fang, D Cousins, G Zhang, S Gu, ... The Journal of Immunology 181 (4), 2790-2798, 2008 | 474 | 2008 |
Rhinovirus-induced IL-25 in asthma exacerbation drives type 2 immunity and allergic pulmonary inflammation J Beale, A Jayaraman, DJ Jackson, JDR Macintyre, MR Edwards, ... Science translational medicine 6 (256), 256ra134-256ra134, 2014 | 368 | 2014 |
Ligation of TLR9 induced on human IL-10–secreting Tregs by 1α, 25-dihydroxyvitamin D3 abrogates regulatory function Z Urry, E Xystrakis, DF Richards, J McDonald, Z Sattar, DJ Cousins, ... The Journal of clinical investigation 119 (2), 387-398, 2009 | 285 | 2009 |
Cytokine coexpression during human Th1/Th2 cell differentiation: direct evidence for coordinated expression of Th2 cytokines DJ Cousins, TH Lee, DZ Staynov The Journal of Immunology 169 (5), 2498-2506, 2002 | 257 | 2002 |
Diminished sarco/endoplasmic reticulum Ca2+ ATPase (SERCA) expression contributes to airway remodelling in bronchial asthma K Mahn, SJ Hirst, S Ying, MR Holt, P Lavender, OO Ojo, L Siew, ... Proceedings of the National Academy of Sciences 106 (26), 10775-10780, 2009 | 195 | 2009 |
DNA methylation changes at human Th2 cytokine genes coincide with DNase I hypersensitive site formation during CD4+ T cell differentiation S Santangelo, DJ Cousins, NEE Winkelmann, DZ Staynov The Journal of Immunology 169 (4), 1893-1903, 2002 | 135 | 2002 |
IL-9 is a key component of memory TH cell peanut-specific responses from children with peanut allergy HA Brough, DJ Cousins, A Munteanu, YF Wong, A Sudra, K Makinson, ... Journal of allergy and clinical immunology 134 (6), 1329-1338. e10, 2014 | 107 | 2014 |
IL-25/IL-33–responsive TH2 cells characterize nasal polyps with a default TH17 signature in nasal mucosa EPS Lam, HH Kariyawasam, BMJ Rana, SR Durham, ANJ McKenzie, ... Journal of Allergy and Clinical Immunology 137 (5), 1514-1524, 2016 | 102 | 2016 |
Human retinoic acid–regulated CD161+ regulatory T cells support wound repair in intestinal mucosa GAM Povoleri, E Nova-Lamperti, C Scottà, G Fanelli, YC Chen, PD Becker, ... Nature immunology 19 (12), 1403-1414, 2018 | 97 | 2018 |
Effects of vitamin D on inflammatory and oxidative stress responses of human bronchial epithelial cells exposed to particulate matter PE Pfeffer, H Lu, EH Mann, YH Chen, TR Ho, DJ Cousins, C Corrigan, ... PloS one 13 (8), e0200040, 2018 | 95 | 2018 |
Group 2 innate lymphoid cells express functional NKp30 receptor inducing type 2 cytokine production M Salimi, L Xue, H Jolin, C Hardman, DJ Cousins, ANJ McKenzie, ... The Journal of Immunology 196 (1), 45-54, 2016 | 95 | 2016 |
Repression of interleukin-5 transcription by the glucocorticoid receptor targets GATA3 signaling and involves histone deacetylase recruitment YK Jee, J Gilmour, A Kelly, H Bowen, D Richards, C Soh, P Smith, ... Journal of Biological Chemistry 280 (24), 23243-23250, 2005 | 91 | 2005 |
Mucosal type 2 innate lymphoid cells are a key component of the allergic response to aeroallergen J Dhariwal, A Cameron, M Trujillo-Torralbo, A del Rosario, E Bakhsoliani, ... American Thoracic Society, 2017 | 87 | 2017 |
Risankizumab in severe asthma—a phase 2a, placebo-controlled trial CE Brightling, P Nair, DJ Cousins, R Louis, D Singh New England Journal of Medicine 385 (18), 1669-1679, 2021 | 74 | 2021 |
T-bet activates Th1 genes through mediator and the super elongation complex A Hertweck, CM Evans, M Eskandarpour, JCH Lau, K Oleinika, I Jackson, ... Cell reports 15 (12), 2756-2770, 2016 | 70 | 2016 |
CD1a presentation of endogenous antigens by group 2 innate lymphoid cells CS Hardman, YL Chen, M Salimi, R Jarrett, D Johnson, VJ Järvinen, ... Science immunology 2 (18), eaan5918, 2017 | 69 | 2017 |
Vitamin D enhances production of soluble ST2, inhibiting the action of IL-33 PE Pfeffer, YH Chen, G Woszczek, NC Matthews, E Chevretton, A Gupta, ... Journal of Allergy and Clinical Immunology 135 (3), 824-827. e3, 2015 | 65 | 2015 |
Analysis of intergenic transcription in the human IL-4/IL-13 gene cluster DF Rogan, DJ Cousins, S Santangelo, PA Ioannou, M Antoniou, TH Lee, ... Proceedings of the National Academy of Sciences of the United States of …, 2004 | 63 | 2004 |