Synthesis and direct assay of large macrocycle diversities by combinatorial late-stage modification at picomole scale S Habeshian, ML Merz, G Sangouard, GK Mothukuri, M Schüttel, ... Nature Communications 13 (3823), 2022 | 22 | 2022 |
Solid-phase peptide synthesis on disulfide-linker resin followed by reductive release affords pure thiol-functionalized peptides Z Bognar, GK Mothukuri, AL Nielsen, ML Merz, PMF Pânzar, C Heinis Organic & Biomolecular Chemistry 20 (29), 5699-5703, 2022 | 11 | 2022 |
Cyclative Release Strategy to Obtain Pure Cyclic Peptides Directly from the Solid Phase S Habeshian, GA Sable, M Schüttel, ML Merz, C Heinis ACS Chem. Biol. 17 (1), 181-186, 2022 | 11 | 2022 |
De novo development of small cyclic peptides that are orally bioavailable ML Merz, S Habeshian, B Li, JAGL David, AL Nielsen, X Ji, K Il Khwildy, ... Nature Chemical Biology 20 (5), 624-633, 2024 | 6 | 2024 |
Development of cyclic peptides that can be administered orally to inhibit disease targets ML Merz, C Heinis Nature Chemical Biology, 2023 | 1 | 2023 |
Research briefing ML Merz, C Heinis Nature Chemical Biology 20, 551-552, 2024 | | 2024 |
Large Libraries of Structurally Diverse Macrocycles Suitable for Membrane Permeation AL Nielsen, Z Bognar, GK Mothukuri, A Zarda, M Schüttel, ML Merz, X Ji, ... Angewandte Chemie, e202400350, 2024 | | 2024 |
De novo developed small cyclic peptides that are orally available ML Merz EPFL, 2022 | | 2022 |
Method for preparing a library of peptides or a peptide C Heinis, S Habeshian, GK Mothukuri, M Schüttel, M Merz, G Sangouard, ... | | 2022 |
Angewandte AL Nielsen, Z Bognar, GK Mothukuri, A Zarda, M Schuttel, ML Merz, X Ji, ... | | |