Paradigms of lung microbiota functions in health and disease, particularly, in asthma E Mathieu, U Escribano-Vazquez, D Descamps, C Cherbuy, P Langella, ... Frontiers in physiology 9, 1168, 2018 | 224 | 2018 |
De novo protein design enables the precise induction of RSV-neutralizing antibodies F Sesterhenn, C Yang, J Bonet, JT Cramer, X Wen, Y Wang, CI Chiang, ... Science 368 (6492), eaay5051, 2020 | 178 | 2020 |
Respiratory syncytial virus infects regulatory B cells in human neonates via chemokine receptor CX3CR1 and promotes lung disease severity D Zhivaki, S Lemoine, A Lim, A Morva, PO Vidalain, L Schandene, ... Immunity 46 (2), 301-314, 2017 | 153 | 2017 |
Modifying the protease, antiprotease pattern by elafin overexpression protects mice from colitis JP Motta, L Magne, D Descamps, C Rolland, C Squarzoni–Dale, ... Gastroenterology 140 (4), 1272-1282, 2011 | 147 | 2011 |
Neutrophil Elastase Degrades Cystic Fibrosis Transmembrane Conductance Regulator via Calpains and Disables Channel Function In Vitro and In Vivo M Le Gars, D Descamps, D Roussel, E Saussereau, L Guillot, M Ruffin, ... American journal of respiratory and critical care medicine 187 (2), 170-179, 2013 | 128 | 2013 |
Toll-like receptor 5 (TLR5), IL-1β secretion, and asparagine endopeptidase are critical factors for alveolar macrophage phagocytosis and bacterial killing D Descamps, M Le Gars, V Balloy, D Barbier, S Maschalidi, M Tohme, ... Proceedings of the National Academy of Sciences 109 (5), 1619-1624, 2012 | 116 | 2012 |
Substitution of hexon hypervariable region 5 of adenovirus serotype 5 abrogates blood factor binding and limits gene transfer to liver F Vigant, D Descamps, B Jullienne, S Esselin, E Connault, P Opolon, ... Molecular Therapy 16 (8), 1474-1480, 2008 | 105 | 2008 |
Bacteria isolated from lung modulate asthma susceptibility in mice A Remot, D Descamps, ML Noordine, A Boukadiri, E Mathieu, V Robert, ... The ISME journal 11 (5), 1061-1074, 2017 | 101 | 2017 |
Influenza A induces the major secreted airway mucin MUC5AC in a protease–EGFR–extracellular regulated kinase–Sp1–dependent pathway D Barbier, I Garcia-Verdugo, J Pothlichet, R Khazen, D Descamps, ... American journal of respiratory cell and molecular biology 47 (2), 149-157, 2012 | 97 | 2012 |
Transcriptomic analysis of host immune and cell death responses associated with the influenza A virus PB1-F2 protein R Le Goffic, O Leymarie, C Chevalier, E Rebours, B Da Costa, J Vidic, ... PLoS pathogens 7 (8), e1002202, 2011 | 86 | 2011 |
Asparagine endopeptidase controls anti-influenza virus immune responses through TLR7 activation S Maschalidi, S Hässler, F Blanc, FE Sepulveda, M Tohme, M Chignard, ... Public Library of Science 8 (8), e1002841, 2012 | 79 | 2012 |
Two key challenges for effective adenovirus-mediated liver gene therapy: innate immune responses and hepatocyte-specific transduction D Descamps, K Benihoud Current gene therapy 9 (2), 115-127, 2009 | 71 | 2009 |
Respective roles of TNF-α and IL-6 in the immune response-elicited by adenovirus-mediated gene transfer in mice K Benihoud, S Esselin, D Descamps, B Jullienne, B Salone, P Bobe, ... Gene therapy 14 (6), 533-544, 2007 | 56 | 2007 |
IRAP+ endosomes restrict TLR9 activation and signaling J Babdor, D Descamps, AC Adiko, M Tohmé, S Maschalidi, I Evnouchidou, ... Nature Immunology 18 (5), 509-518, 2017 | 49 | 2017 |
Lung protease/anti-protease network and modulation of mucus production and surfactant activity I Garcia-Verdugo, D Descamps, M Chignard, L Touqui, JM Sallenave Biochimie 92 (11), 1608-1617, 2010 | 49 | 2010 |
Porcine alveolar macrophage-like cells are pro-inflammatory pulmonary intravascular macrophages that produce large titers of porcine reproductive and respiratory syndrome virus E Bordet, P Maisonnasse, P Renson, E Bouguyon, E Crisci, M Tiret, ... Scientific reports 8 (1), 10172, 2018 | 46 | 2018 |
Boosting subdominant neutralizing antibody responses with a computationally designed epitope-focused immunogen F Sesterhenn, M Galloux, SS Vollers, L Csepregi, C Yang, D Descamps, ... PLoS biology 17 (2), e3000164, 2019 | 43 | 2019 |
Respiratory syncytial virus tropism for olfactory sensory neurons in mice B Bryche, M Frétaud, A Saint‐Albin Deliot, M Galloux, L Sedano, ... Journal of Neurochemistry 155 (2), 137-153, 2020 | 42 | 2020 |
Pulmonary susceptibility of neonates to respiratory syncytial virus infection: a problem of innate immunity? C Drajac, D Laubreton, S Riffault, D Descamps Journal of Immunology Research 2017, 2017 | 38 | 2017 |
RSV N-nanorings fused to palivizumab-targeted neutralizing epitope as a nanoparticle RSV vaccine PL Hervé, C Deloizy, D Descamps, MA Rameix-Welti, J Fix, JS McLellan, ... Nanomedicine: Nanotechnology, Biology and Medicine 13 (2), 411-420, 2017 | 33 | 2017 |