Cytochrome P450 structure, function and clinical significance: a review P Manikandan, S Nagini Current drug targets 19 (1), 38-54, 2018 | 708 | 2018 |
The neem limonoids azadirachtin and nimbolide inhibit hamster cheek pouch carcinogenesis by modulating xenobiotic-metabolizing enzymes, DNA damage, antioxidants, invasion and … RV Priyadarsini, P Manikandan, GH Kumar, S Nagini Free radical research 43 (5), 492-504, 2009 | 142 | 2009 |
Eugenol induces apoptosis and inhibits invasion and angiogenesis in a rat model of gastric carcinogenesis induced by MNNG P Manikandan, RS Murugan, RV Priyadarsini, G Vinothini, S Nagini Life sciences 86 (25-26), 936-941, 2010 | 125 | 2010 |
Evaluation of Azadirachta indica leaf fractions for in vitro antioxidant potential and in vivo modulation of biomarkers of chemoprevention in the hamster buccal pouch … P Manikandan, PV Letchoumy, M Gopalakrishnan, S Nagini Food and Chemical Toxicology 46 (7), 2332-2343, 2008 | 113 | 2008 |
Eugenol inhibits cell proliferation via NF-κB suppression in a rat model of gastric carcinogenesis induced by MNNG P Manikandan, G Vinothini, R Vidya Priyadarsini, D Prathiba, S Nagini Investigational new drugs 29, 110-117, 2011 | 108 | 2011 |
The flavonoid quercetin modulates the hallmark capabilities of hamster buccal pouch tumors RV Priyadarsini, G Vinothini, RS Murugan, P Manikandan, S Nagini Nutrition and cancer 63 (2), 218-226, 2011 | 106 | 2011 |
Ocimum sanctum Linn. (Holy Basil) Ethanolic Leaf Extract Protects Against 7,12-Dimethylbenz[a]Anthracene-Induced Genotoxicity, Oxidative Stress, and … P Manikandan, RS Murugan, H Abbas, SK Abraham, S Nagini Journal of medicinal food 10 (3), 495-502, 2007 | 70 | 2007 |
Recruitment of DNA polymerase eta by FANCD2 in the early response to DNA damage D Fu, F Dudimah, J Zhang, A Pickering, J Paneerselvam, M Palrasu, ... Cell cycle 12 (5), 803-809, 2013 | 62 | 2013 |
Evaluation of Azadirachta indica Leaf Fractions for in Vitro Antioxidant Potential and Protective Effects against H2O2-Induced Oxidative Damage to pBR322 DNA … P Manikandan, R Anandan, S Nagini Journal of agricultural and food chemistry 57 (15), 6990-6996, 2009 | 61 | 2009 |
Chemoprevention of rat mammary carcinogenesis by Azadirachta indica leaf fractions: modulation of hormone status, xenobiotic-metabolizing enzymes, oxidative stress, cell … G Vinothini, P Manikandan, R Anandan, S Nagini Food and Chemical Toxicology 47 (8), 1852-1863, 2009 | 52 | 2009 |
Combinatorial chemopreventive effect of Azadirachta indica and Ocimum sanctum on oxidant-antioxidant status, cell proliferation, apoptosis and angiogenesis in a rat forestomach … P Manikandan, P Vidjaya Letchoumy, D Prathiba, S Nagini Singapore medical journal 49 (10), 814, 2008 | 50 | 2008 |
Bacterial CagA protein compromises tumor suppressor mechanisms in gastric epithelial cells M Palrasu, E Zaika, W El-Rifai, M Garcia-Buitrago, MB Piazuelo, ... The Journal of clinical investigation 130 (5), 2422-2434, 2020 | 45 | 2020 |
Proliferation, angiogenesis and apoptosis-associated proteins are molecular targets for chemoprevention of MNNG-induced gastric carcinogenesis by ethanolic Ocimum sanctum leaf … P Manikandan, V Letchoumy, D Prathiba, S Nagini Singapore medical journal 48 (7), 645-651, 2007 | 45 | 2007 |
Nimbolide, a neem limonoid, is a promising candidate for the anticancer drug arsenal S Nagini, R Nivetha, M Palrasu, R Mishra Journal of medicinal chemistry 64 (7), 3560-3577, 2021 | 38 | 2021 |
Helicobacter pylori pathogen regulates p14ARF tumor suppressor and autophagy in gastric epithelial cells A Horvat, JM Noto, B Ramatchandirin, E Zaika, M Palrasu, J Wei, ... Oncogene 37 (37), 5054-5065, 2018 | 36 | 2018 |
Synthesis of 4-methyl-N′-(3-alkyl-2r, 6c-diarylpiperidin-4-ylidene)-1, 2, 3-thiadiazole-5-carbohydrazides with antioxidant, antitumor and antimicrobial activities K Paulrasu, A Duraikannu, M Palrasu, A Shanmugasundaram, ... Organic & biomolecular chemistry 12 (31), 5911-5921, 2014 | 33 | 2014 |
Investigation of the chemopreventive potential of neem leaf subfractions in the hamster buccal pouch model and phytochemical characterization P Manikandan, SM Ramalingam, G Vinothini, VP Ramamurthi, IP Singh, ... European Journal of Medicinal Chemistry 56, 271-281, 2012 | 32 | 2012 |
Role of bacterial and viral pathogens in gastric carcinogenesis M Palrasu, E Zaika, W El-Rifai, J Que, AI Zaika Cancers 13 (8), 1878, 2021 | 24 | 2021 |
Helicobacter pylori pathogen inhibits cellular responses to oncogenic stress and apoptosis M Palrasu, E Zaika, K Paulrasu, R Caspa Gokulan, G Suarez, J Que, ... PLoS pathogens 18 (6), e1010628, 2022 | 14 | 2022 |
A novel probe for spliceosomal proteins that induces autophagy and death of melanoma cells reveals new targets for melanoma drug discovery M Palrasu, AM Knapinska, J Diez, L Smith, T LaVoi, M Giulianotti, ... Cellular physiology and biochemistry: international journal of experimental …, 2019 | 14 | 2019 |