| Snake venomics and antivenomics: Proteomic tools in the design and control of antivenoms for the treatment of snakebite envenoming JM Gutiérrez, B Lomonte, G León, A Alape-Giron, M Flores-Díaz, L Sanz, ... Journal of proteomics 72 (2), 165-182, 2009 | 261 | 2009 |
| Pharmacokinetic-pharmacodynamic relationships of immunoglobulin therapy for envenomation JM Gutiérrez, G León, B Lomonte Clinical pharmacokinetics 42, 721-741, 2003 | 256 | 2003 |
| Snake venomics of African spitting cobras: toxin composition and assessment of congeneric cross-reactivity of the pan-African EchiTAb-Plus-ICP antivenom by antivenomics and … D Petras, L Sanz, A Segura, M Herrera, M Villalta, D Solano, M Vargas, ... Journal of proteome research 10 (3), 1266-1280, 2011 | 235 | 2011 |
| Neutralization of local tissue damage induced by Bothrops asper (terciopelo) snake venom JM Gutiérrez, G León, G Rojas, B Lomonte, A Rucavado, F Chaves Toxicon 36 (11), 1529-1538, 1998 | 232 | 1998 |
| Trends in snakebite envenomation therapy: scientific, technological and public health considerations JM Gutierrez, B Lomonte, G León, A Rucavado, F Chaves, Y Angulo Current pharmaceutical design 13 (28), 2935-2950, 2007 | 202 | 2007 |
| Antivenoms for the treatment of snakebite envenomings: the road ahead JM Gutiérrez, G León, T Burnouf Biologicals 39 (3), 129-142, 2011 | 190 | 2011 |
| Pathogenic mechanisms underlying adverse reactions induced by intravenous administration of snake antivenoms G León, M Herrera, Á Segura, M Villalta, M Vargas, JM Gutiérrez Toxicon 76, 63-76, 2013 | 169 | 2013 |
| A randomized blinded clinical trial of two antivenoms, prepared by caprylic acid or ammonium sulphate fractionation of IgG, in Bothrops and Porthidium snake bites in Colombia … R Otero, JM Gutiérrez, G Rojas, V Núñez, A Dıaz, E Miranda, AF Uribe, ... Toxicon 37 (6), 895-908, 1999 | 159 | 1999 |
| Preclinical evaluation of the efficacy of antivenoms for snakebite envenoming: State-of-the-art and challenges ahead JM Gutiérrez, G Solano, D Pla, M Herrera, Á Segura, M Vargas, M Villalta, ... Toxins 9 (5), 163, 2017 | 157 | 2017 |
| Antivenoms for snakebite envenomings J Maria Gutierrez, G León, B Lomonte, Y Angulo Inflammation & Allergy-Drug Targets (Formerly Current Drug Targets …, 2011 | 156 | 2011 |
| Inhibition of local hemorrhage and dermonecrosis induced by Bothrops asper snake venom: effectiveness of early in situ administration of the peptidomimetic metalloproteinase … A Rucavado, T Escalante, A Franceschi, F Chaves, G León, Y Cury, ... The American journal of tropical medicine and hygiene 63 (5), 313-319, 2000 | 153 | 2000 |
| Immune response towards snake venoms G León, L Sánchez, A Hernández, M Villalta, M Herrera, A Segura, ... Inflammation & Allergy-Drug Targets (Formerly Current Drug Targets …, 2011 | 145 | 2011 |
| Pan-African polyspecific antivenom produced by caprylic acid purification of horse IgG: an alternative to the antivenom crisis in Africa JM Gutiérrez, E Rojas, L Quesada, G León, J Núñez, GD Laing, M Sasa, ... Transactions of the royal society of tropical medicine and hygiene 99 (6 …, 2005 | 129 | 2005 |
| Preclinical assessment of the neutralizing capacity of antivenoms produced in six Latin American countries against medically-relevant Bothrops snake venoms A Segura, MC Castillo, V Núñez, A Yarlequé, LRC Gonçalves, M Villalta, ... Toxicon 56 (6), 980-989, 2010 | 119 | 2010 |
| Phylovenomics of Daboia russelii across the Indian subcontinent. Bioactivities and comparative in vivo neutralization and in vitro third-generation antivenomics of antivenoms … D Pla, L Sanz, S Quesada-Bernat, M Villalta, J Baal, MAW Chowdhury, ... Journal of proteomics 207, 103443, 2019 | 110 | 2019 |
| Role bending: complex relationships between viruses, hosts, and vectors related to citrus leprosis, an emerging disease A Roy, JS Hartung, WL Schneider, J Shao, G Leon, MJ Melzer, JJ Beard, ... Phytopathology 105 (7), 1013-1025, 2015 | 109 | 2015 |
| Efficacy and safety of two whole IgG polyvalent antivenoms, refined by caprylic acid fractionation with or without β-propiolactone, in the treatment of Bothrops asper bites in … R Otero, G León, JM Gutiérrez, G Rojas, MF Toro, J Barona, V Rodríguez, ... Transactions of the Royal Society of Tropical Medicine and Hygiene 100 (12 …, 2006 | 100 | 2006 |
| Neutralization of Bothrops asper venom by antibodies, natural products and synthetic drugs: contributions to understanding snakebite envenomings and their treatment B Lomonte, G Leon, Y Angulo, A Rucavado, V Nunez Toxicon 54 (7), 1012-1028, 2009 | 94 | 2009 |
| Impact of Regional Variation in Bothrops asper Snake Venom on the Design of Antivenoms: Integrating Antivenomics and Neutralization Approaches JM Gutiérrez, L Sanz, M Flores-Díaz, L Figueroa, M Madrigal, M Herrera, ... Journal of Proteome Research 9 (1), 564-577, 2010 | 91 | 2010 |
| Current technology for the industrial manufacture of snake antivenoms G León, M Vargas, Á Segura, M Herrera, M Villalta, A Sánchez, G Solano, ... Toxicon 151, 63-73, 2018 | 90 | 2018 |
