mTOR inhibition decreases SOX2-SOX9 mediated glioma stem cell activity and temozolomide resistance L Garros-Regulez, P Aldaz, O Arrizabalaga, V Moncho-Amor, ... Expert opinion on therapeutic targets 20 (4), 393-405, 2016 | 140 | 2016 |
Targeting SOX2 as a therapeutic strategy in glioblastoma L Garros-Regulez, I Garcia, E Carrasco-Garcia, A Lantero, P Aldaz, ... Frontiers in oncology 6, 222, 2016 | 122 | 2016 |
SOX9 elevation acts with canonical WNT signaling to drive gastric cancer progression JC Santos, E Carrasco-Garcia, M Garcia-Puga, P Aldaz, M Montes, ... Cancer research 76 (22), 6735-6746, 2016 | 116 | 2016 |
Liquid biopsy in glioblastoma: opportunities, applications and challenges A Saenz-Antoñanzas, J Auzmendi-Iriarte, E Carrasco-Garcia, ... Cancers 11 (7), 950, 2019 | 106 | 2019 |
Role of receptor tyrosine kinases and their ligands in glioblastoma E Carrasco-García, M Saceda, I Martínez-Lacaci Cells 3 (2), 199-235, 2014 | 92 | 2014 |
Inhibition of Hsp90 function by ansamycins causes downregulation of cdc2 and cdc25c and G2/M arrest in glioblastoma cell lines P Garcia-Morales, E Carrasco-Garcia, P Ruiz-Rico, R Martinez-Mira, ... Oncogene 26 (51), 7185-7193, 2007 | 80 | 2007 |
Small tyrosine kinase inhibitors interrupt EGFR signaling by interacting with erbB3 and erbB4 in glioblastoma cell lines E Carrasco-García, M Saceda, S Grasso, L Rocamora-Reverte, M Conde, ... Experimental cell research 317 (10), 1476-1489, 2011 | 71 | 2011 |
Histone deacetylase inhibitors induced caspase-independent apoptosis in human pancreatic adenocarcinoma cell lines P García-Morales, A Gómez-Martínez, A Carrato, I Martínez-Lacaci, ... Molecular cancer therapeutics 4 (8), 1222-1230, 2005 | 70 | 2005 |
Study of the anticancer properties of tin (IV) carboxylate complexes on a panel of human tumor cell lines L Rocamora‐Reverte, E Carrasco‐García, J Ceballos‐Torres, S Prashar, ... ChemMedChem 7 (2), 301-310, 2012 | 68 | 2012 |
Relevance of oxidative stress and inflammation in frailty based on human studies and mouse models M Álvarez-Satta, A Berna-Erro, E Carrasco-Garcia, A Alberro, ... Aging (Albany NY) 12 (10), 9982, 2020 | 58 | 2020 |
SOX9-regulated cell plasticity in colorectal metastasis is attenuated by rapamycin E Carrasco-Garcia, L Lopez, P Aldaz, S Arevalo, J Aldaregia, L Egaña, ... Scientific reports 6 (1), 32350, 2016 | 55 | 2016 |
Increased Arf/p53 activity in stem cells, aging and cancer E Carrasco‐Garcia, M Moreno, L Moreno‐Cugnon, A Matheu Aging cell 16 (2), 219-225, 2017 | 53 | 2017 |
Paradoxical role of SOX2 in gastric cancer E Carrasco-Garcia, JC Santos, I Garcia, M Brianti, M García-Puga, ... American journal of cancer research 6 (4), 701, 2016 | 53 | 2016 |
Post-transcriptional regulation of P-glycoprotein expression in cancer cell lines A Gómez-Martínez, P García-Morales, A Carrato, MD Castro-Galache, ... Molecular cancer research 5 (6), 641-653, 2007 | 48 | 2007 |
Increased gene dosage of Ink4/Arf and p53 delays age‐associated central nervous system functional decline E Carrasco‐Garcia, O Arrizabalaga, M Serrano, R Lovell‐Badge, ... Aging Cell 14 (4), 710-714, 2015 | 44 | 2015 |
Characterization of a new small-molecule inhibitor of HDAC6 in glioblastoma J Auzmendi-Iriarte, A Saenz-Antoñanzas, I Mikelez-Alonso, ... Cell death & disease 11 (6), 417, 2020 | 42 | 2020 |
Cyclin D3 is down-regulated by rapamycin in HER-2-overexpressing breast cancer cells P García-Morales, E Hernando, E Carrasco-García, ... Molecular cancer therapeutics 5 (9), 2172-2181, 2006 | 41 | 2006 |
Resistance to Selumetinib (AZD6244) in colorectal cancer cell lines is mediated by p70S6K and RPS6 activation S Grasso, E Tristante, M Saceda, P Carbonell, L Mayor-López, ... Neoplasia 16 (10), 845-860, 2014 | 40 | 2014 |
SOX9 promotes tumor progression through the axis BMI1-p21CIP P Aldaz, M Otaegi-Ugartemendia, A Saenz-Antonanzas, M Garcia-Puga, ... Scientific reports 10 (1), 357, 2020 | 39 | 2020 |
SOX2 expression diminishes with ageing in several tissues in mice and humans E Carrasco-Garcia, L Moreno-Cugnon, I Garcia, C Borras, M Revuelta, ... Mechanisms of Ageing and Development 177, 30-36, 2019 | 37 | 2019 |