Architectural protein subclasses shape 3D organization of genomes during lineage commitment JE Phillips-Cremins, MEG Sauria, A Sanyal, TI Gerasimova, BR Lajoie, ... Cell 153 (6), 1281-1295, 2013 | 1264 | 2013 |
CTCF: an architectural protein bridging genome topology and function CT Ong, VG Corces Nature Reviews Genetics 15 (4), 234-246, 2014 | 1252 | 2014 |
Enhancer function: new insights into the regulation of tissue-specific gene expression CT Ong, VG Corces Nature Reviews Genetics 12 (4), 283-293, 2011 | 1063 | 2011 |
Widespread rearrangement of 3D chromatin organization underlies polycomb-mediated stress-induced silencing L Li, X Lyu, C Hou, N Takenaka, HQ Nguyen, CT Ong, C Cubeñas-Potts, ... Molecular cell 58 (2), 216-231, 2015 | 332 | 2015 |
Insulator function and topological domain border strength scale with architectural protein occupancy K Van Bortle, MH Nichols, L Li, CT Ong, N Takenaka, ZS Qin, VG Corces Genome biology 15, 1-18, 2014 | 318 | 2014 |
NOTCH1 regulates osteoclastogenesis directly in osteoclast precursors and indirectly via osteoblast lineage cells S Bai, R Kopan, W Zou, MJ Hilton, C Ong, F Long, FP Ross, ... Journal of Biological Chemistry 283 (10), 6509-6518, 2008 | 278 | 2008 |
Target selectivity of vertebrate notch proteins: Collaboration between discrete domains and CSL-binding site architecture determines activation probability CT Ong, HT Cheng, LW Chang, T Ohtsuka, R Kageyama, GD Stormo, ... Journal of Biological Chemistry 281 (8), 5106-5119, 2006 | 258 | 2006 |
Enhancers: emerging roles in cell fate specification CT Ong, VG Corces EMBO reports 13 (5), 423-430, 2012 | 174 | 2012 |
Mapping the consequence of Notch1 proteolysis in vivo with NIP-CRE M Vooijs, CT Ong, B Hadland, S Huppert, Z Liu, J Korving, ... Oxford University Press for The Company of Biologists Limited 134 (3), 535-544, 2007 | 169 | 2007 |
Molecular analysis of genetic differences between virulent and avirulent strains of Aeromonas hydrophila isolated from diseased fish YL Zhang, CT Ong, KY Leung Microbiology 146 (4), 999-1009, 2000 | 152 | 2000 |
Notch and presenilin regulate cellular expansion and cytokine secretion but cannot instruct Th1/Th2 fate acquisition CT Ong, JR Sedy, KM Murphy, R Kopan PloS one 3 (7), e2823, 2008 | 121 | 2008 |
Increased intron retention is a post‐transcriptional signature associated with progressive aging and Alzheimer’s disease S Adusumalli, ZK Ngian, WQ Lin, T Benoukraf, CT Ong Aging cell 18 (3), e12928, 2019 | 105 | 2019 |
Poly (ADP-ribosyl) ation regulates insulator function and intrachromosomal interactions in Drosophila CT Ong, K Van Bortle, E Ramos, VG Corces Cell 155 (1), 148-159, 2013 | 79 | 2013 |
Membrane Targeting and Asymmetric Localization of Drosophila Partner of Inscuteable Are Discrete Steps Controlled by Distinct Regions of the Protein F Yu, CT Ong, W Chia, X Yang Molecular and Cellular Biology 22 (12), 4230-4240, 2002 | 49 | 2002 |
Insulators as mediators of intra-and inter-chromosomal interactions: a common evolutionary theme CT Ong, VG Corces Journal of biology 8, 1-4, 2009 | 29 | 2009 |
Increased intron retention is linked to Alzheimer’s disease CT Ong, S Adusumalli Neural regeneration research 15 (2), 259-260, 2020 | 19 | 2020 |
Truncated Tau caused by intron retention is enriched in Alzheimer’s disease cortex and exhibits altered biochemical properties ZK Ngian, YY Tan, CT Choo, WQ Lin, CY Leow, SJ Mah, MKP Lai, ... Proceedings of the National Academy of Sciences 119 (37), e2204179119, 2022 | 15 | 2022 |
Phosphorylation of Tet3 by cdk5 is critical for robust activation of BRN2 during neuronal differentiation VK Rao, A Swarnaseetha, GH Tham, WQ Lin, BB Han, T Benoukraf, ... Nucleic Acids Research 48 (3), 1225-1238, 2020 | 15 | 2020 |
Modulation of CTCF insulator function by transcription of a noncoding RNA CT Ong, VG Corces Developmental cell 15 (4), 489-490, 2008 | 15 | 2008 |
E2F and STAT3 provide transcriptional synergy for histone variant H2AZ activation to sustain glioblastoma chromatin accessibility and tumorigenicity J Yoon, OV Grinchuk, R Tirado-Magallanes, ZK Ngian, EXY Tay, ... Cell Death & Differentiation 29 (7), 1379-1394, 2022 | 12 | 2022 |