| The structural basis of Janus kinase 2 inhibition by a potent and specific pan-Janus kinase inhibitor IS Lucet, E Fantino, M Styles, R Bamert, O Patel, SE Broughton, M Walter, ... Blood 107 (1), 176-183, 2006 | 331 | 2006 |
| The GM–CSF/IL‐3/IL‐5 cytokine receptor family: from ligand recognition to initiation of signaling SE Broughton, U Dhagat, TR Hercus, TL Nero, MA Grimbaldeston, ... Immunological reviews 250 (1), 277-302, 2012 | 262 | 2012 |
| Biased T cell receptor usage directed against human leukocyte antigen DQ8-restricted gliadin peptides is associated with celiac disease SE Broughton, J Petersen, A Theodossis, SW Scally, KL Loh, ... Immunity 37 (4), 611-621, 2012 | 148 | 2012 |
| Signalling by the βc family of cytokines TR Hercus, U Dhagat, WLT Kan, SE Broughton, TL Nero, M Perugini, ... Cytokine & growth factor reviews 24 (3), 189-201, 2013 | 105 | 2013 |
| The βc receptor family–Structural insights and their functional implications SE Broughton, TL Nero, U Dhagat, WL Kan, TR Hercus, D Tvorogov, ... Cytokine 74 (2), 247-258, 2015 | 87 | 2015 |
| The GM-CSF receptor family: mechanism of activation and implications for disease TR Hercus, SE Broughton, PG Ekert, HS Ramshaw, M Perugini, ... Growth factors 30 (2), 63-75, 2012 | 86 | 2012 |
| The 2.7 Å crystal structure of the autoinhibited human c-Fms kinase domain M Walter, IS Lucet, O Patel, SE Broughton, R Bamert, NK Williams, ... Journal of molecular biology 367 (3), 839-847, 2007 | 82 | 2007 |
| Dual mechanism of interleukin-3 receptor blockade by an anti-cancer antibody SE Broughton, TR Hercus, MP Hardy, BJ McClure, TL Nero, M Dottore, ... Cell reports 8 (2), 410-419, 2014 | 56 | 2014 |
| Conformational changes in the GM-CSF receptor suggest a molecular mechanism for affinity conversion and receptor signaling SE Broughton, TR Hercus, TL Nero, M Dottore, BJ McClure, U Dhagat, ... Structure 24 (8), 1271-1281, 2016 | 48 | 2016 |
| Role of the β Common (βc) Family of Cytokines in Health and Disease TR Hercus, WLT Kan, SE Broughton, D Tvorogov, HS Ramshaw, ... Cold Spring Harbor Perspectives in Biology 10 (6), a028514, 2018 | 47 | 2018 |
| Cytokine receptor activation at the cell surface SE Broughton, TR Hercus, AF Lopez, MW Parker Current opinion in structural biology 22 (3), 350-359, 2012 | 44 | 2012 |
| A dual role for the N-terminal domain of the IL-3 receptor in cell signalling SE Broughton, TR Hercus, TL Nero, WL Kan, EF Barry, M Dottore, ... Nature communications 9 (1), 386, 2018 | 41 | 2018 |
| EPO does not promote interaction between the erythropoietin and beta-common receptors KS Cheung Tung Shing, SE Broughton, TL Nero, K Gillinder, MD Ilsley, ... Scientific reports 8 (1), 12457, 2018 | 29 | 2018 |
| The production and crystallization of the human leukocyte antigen class II molecules HLA-DQ2 and HLA-DQ8 complexed with deamidated gliadin peptides implicated in coeliac disease KN Henderson, HH Reid, NA Borg, SE Broughton, T Huyton, ... Acta Crystallographica Section F: Structural Biology and Crystallization …, 2007 | 24 | 2007 |
| Crystallization and preliminary X-ray diffraction analysis of the interleukin-3 alpha receptor bound to the Fab fragment of antibody CSL362 SE Broughton, TR Hercus, TL Nero, U Dhagat, CM Owczarek, MP Hardy, ... Acta Crystallographica Section F: Structural Biology Communications 70 (3 …, 2014 | 13 | 2014 |
| The mechanism of GM-CSF inhibition by human GM-CSF auto-antibodies suggests novel therapeutic opportunities U Dhagat, TR Hercus, SE Broughton, TL Nero, KS Cheung Tung Shing, ... MAbs 10 (7), 1018-1029, 2018 | 10 | 2018 |
| Distinct assemblies of heterodimeric cytokine receptors govern stemness programs in leukemia WL Kan, U Dhagat, KB Kaufmann, TR Hercus, TL Nero, AGX Zeng, ... Cancer Discovery 13 (8), 1922-1947, 2023 | 6 | 2023 |
| Anti il-3r alpha agents and uses thereof AF Lopez, TR Hercus, SE Broughton, MW Parker, N Wilson, M Hardy US Patent App. 15/724,145, 2018 | 2 | 2018 |
| Anti il-3r alpha agents and uses thereof AF Lopez, TR Hercus, SE Broughton, MW Parker, N Wilson, M Hardy US Patent App. 14/775,631, 2016 | 1 | 2016 |
| Unexpected mechanisms of action for a cytokine receptor-blocking antibody TR Hercus, SE Broughton, MP Hardy, TL Nero, NJ Wilson, MW Parker, ... Molecular & Cellular Oncology 1 (4), e969129, 2014 | 1 | 2014 |
