Chronic inflammation promotes myeloid-derived suppressor cell activation blocking antitumor immunity in transgenic mouse melanoma model C Meyer, A Sevko, M Ramacher, AV Bazhin, CS Falk, W Osen, I Borrello, ... Proceedings of the National Academy of Sciences 108 (41), 17111-17116, 2011 | 381 | 2011 |
Myeloid cells and related chronic inflammatory factors as novel predictive markers in melanoma treatment with ipilimumab C Gebhardt, A Sevko, H Jiang, R Lichtenberger, M Reith, K Tarnanidis, ... Clinical Cancer Research 21 (24), 5453-5459, 2015 | 376 | 2015 |
Antitumor effect of paclitaxel is mediated by inhibition of myeloid-derived suppressor cells and chronic inflammation in the spontaneous melanoma model A Sevko, T Michels, M Vrohlings, L Umansky, P Beckhove, M Kato, ... The Journal of Immunology 190 (5), 2464-2471, 2013 | 263 | 2013 |
Extracellular vesicle-mediated transfer of functional RNA in the tumor microenvironment K Ridder, A Sevko, J Heide, M Dams, AK Rupp, J Macas, J Starmann, ... Oncoimmunology 4 (6), e1008371, 2015 | 246 | 2015 |
The TRAIL-induced cancer secretome promotes a tumor-supportive immune microenvironment via CCR2 T Hartwig, A Montinaro, S von Karstedt, A Sevko, S Surinova, ... Molecular cell 65 (4), 730-742. e5, 2017 | 219 | 2017 |
Paclitaxel promotes differentiation of myeloid-derived suppressor cells into dendritic cells in vitro in a TLR4-independent manner T Michels, GV Shurin, H Naiditch, A Sevko, V Umansky, MR Shurin Journal of immunotoxicology 9 (3), 292-300, 2012 | 172 | 2012 |
Tumor microenvironment and myeloid-derived suppressor cells V Umansky, A Sevko Cancer Microenvironment 6, 169-177, 2013 | 169 | 2013 |
Melanoma-induced immunosuppression and its neutralization V Umansky, A Sevko Seminars in cancer biology 22 (4), 319-326, 2012 | 152 | 2012 |
Myeloid-derived suppressor cells interact with tumors in terms of myelopoiesis, tumorigenesis and immunosuppression: thick as thieves A Sevko, V Umansky Journal of Cancer 4 (1), 3, 2013 | 134 | 2013 |
Cyclophosphamide Promotes Chronic Inflammation–Dependent Immunosuppression and Prevents Antitumor Response in Melanoma A Sevko, M Sade-Feldman, J Kanterman, T Michels, CS Falk, L Umansky, ... Journal of Investigative Dermatology 133 (6), 1610-1619, 2013 | 122 | 2013 |
Tadalafil has biologic activity in human melanoma. Results of a pilot trial with Tadalafil in patients with metastatic Melanoma (TaMe) JC Hassel, H Jiang, C Bender, J Winkler, A Sevko, I Shevchenko, ... Oncoimmunology 6 (9), e1326440, 2017 | 89 | 2017 |
Myeloid‐derived suppressor cells in malignant melanoma V Umansky, A Sevko, C Gebhardt, J Utikal JDDG: Journal der Deutschen Dermatologischen Gesellschaft 12 (11), 1021-1027, 2014 | 79 | 2014 |
Skin melanoma development in ret transgenic mice despite the depletion of CD25+ Foxp3+ regulatory T cells in lymphoid organs S Kimpfler, A Sevko, S Ring, C Falk, W Osen, K Frank, M Kato, K Mahnke, ... The Journal of Immunology 183 (10), 6330-6337, 2009 | 76 | 2009 |
Overcoming immunosuppression in the melanoma microenvironment induced by chronic inflammation V Umansky, A Sevko Cancer Immunology, Immunotherapy 61, 275-282, 2012 | 74 | 2012 |
Application of paclitaxel in low non-cytotoxic doses supports vaccination with melanoma antigens in normal mice A Sevko, V Kremer, C Falk, L Umansky, MR Shurin, GV Shurin, ... Journal of immunotoxicology 9 (3), 275-281, 2012 | 71 | 2012 |
Serum inflammatory factors and circulating immunosuppressive cells are predictive markers for efficacy of radiofrequency ablation in non-small-cell lung cancer T Schneider, A Sevko, CP Heussel, L Umansky, P Beckhove, ... Clinical & Experimental Immunology 180 (3), 467-474, 2015 | 51 | 2015 |
The Linear ubiquitin chain assembly complex acts as a liver tumor suppressor and inhibits hepatocyte apoptosis and hepatitis Y Shimizu, N Peltzer, A Sevko, E Lafont, A Sarr, H Draberova, H Walczak Hepatology 65 (6), 1963-1978, 2017 | 35 | 2017 |
Histone deacetylase inhibitor-temozolomide co-treatment inhibits melanoma growth through suppression of Chemokine (CC motif) ligand 2-driven signals L Gatti, A Sevko, M De Cesare, N Arrighetti, G Manenti, E Ciusani, ... Oncotarget 5 (12), 4516, 2014 | 28 | 2014 |
Tumor-specific regulatory T cells from the bone marrow orchestrate antitumor immunity in breast cancer Y Ge, HH Böhm, A Rathinasamy, M Xydia, X Hu, M Pincha, L Umansky, ... Cancer immunology research 7 (12), 1998-2012, 2019 | 23 | 2019 |
Ret transgenic mouse model of spontaneous skin melanoma: focus on regulatory T cells V Umansky, A Sevko Pigment Cell & Melanoma Research 26 (4), 457-463, 2013 | 17 | 2013 |