Oxidative damage to RNA: mechanisms, consequences, and diseases Q Kong, CG Lin Cellular and Molecular Life Sciences 67, 1817-1829, 2010 | 429 | 2010 |
Messenger RNA oxidation occurs early in disease pathogenesis and promotes motor neuron degeneration in ALS Y Chang, Q Kong, X Shan, G Tian, H Ilieva, DW Cleveland, JD Rothstein, ... PloS one 3 (8), e2849, 2008 | 275 | 2008 |
An Rgd Sequence in the P2y2 Receptor Interacts with αVβ3 Integrins and Is Required for Go-Mediated Signal Transduction L Erb, J Liu, J Ockerhausen, Q Kong, RC Garrad, K Griffin, C Neal, ... The Journal of Cell Biology 153 (3), 491-502, 2001 | 199 | 2001 |
Functional P2Y2 Nucleotide Receptors Mediate Uridine 5′-Triphosphate–Induced Intimal Hyperplasia in Collared Rabbit Carotid Arteries CI Seye, Q Kong, L Erb, RC Garrad, B Krugh, M Wang, JT Turner, ... Circulation 106 (21), 2720-2726, 2002 | 160 | 2002 |
Small-molecule activator of glutamate transporter EAAT2 translation provides neuroprotection Q Kong, LC Chang, K Takahashi, Q Liu, DA Schulte, L Lai, B Ibabao, ... The Journal of clinical investigation 124 (3), 1255-1267, 2014 | 159 | 2014 |
P2X7 receptors stimulate AKT phosphorylation in astrocytes MC Jacques‐Silva, R Rodnight, G Lenz, Z Liao, Q Kong, M Tran, Y Kang, ... British journal of pharmacology 141 (7), 1106-1117, 2004 | 154 | 2004 |
Glutamate transporter EAAT2: a new target for the treatment of neurodegenerative diseases CLG Lin, Q Kong, GD Cuny, MA Glicksman Future medicinal chemistry 4 (13), 1689-1700, 2012 | 152 | 2012 |
The P2Y2 nucleotide receptor mediates UTP-induced vascular cell adhesion molecule-1 expression in coronary artery endothelial cells CI Seye, N Yu, R Jain, Q Kong, T Minor, J Newton, L Erb, FA González, ... Journal of biological Chemistry 278 (27), 24960-24965, 2003 | 148 | 2003 |
Restored glial glutamate transporter EAAT2 function as a potential therapeutic approach for Alzheimer’s disease K Takahashi, Q Kong, Y Lin, N Stouffer, DA Schulte, L Lai, Q Liu, ... Journal of experimental medicine 212 (3), 319-332, 2015 | 139 | 2015 |
Purine signaling and potential new therapeutic approach: possible outcomes of NTPDase inhibition FP Gendron, OBB Krugh, Q Kong, GA Weisman, AR Beaudoin Current Drug Targets 3 (3), 229-245, 2002 | 133 | 2002 |
P2Y2 nucleotide receptor interaction with αV integrin mediates astrocyte migration M Wang, Q Kong, FA Gonzalez, G Sun, L Erb, C Seye, GA Weisman Journal of neurochemistry 95 (3), 630-640, 2005 | 119 | 2005 |
Molecular determinants of P2Y2 nucleotide receptor function: Implications for proliferative and inflammatory pathways in astrocytes GA Weisman, M Wang, Q Kong, NE Chorna, JT Neary, GY Sun, ... Molecular neurobiology 31, 169-183, 2005 | 117 | 2005 |
Identification of translational activators of glial glutamate transporter EAAT2 through cell-based high-throughput screening: an approach to prevent excitotoxicity CK Colton, Q Kong, L Lai, MX Zhu, KI Seyb, GD Cuny, J Xian, ... Journal of biomolecular screening 15 (6), 653-662, 2010 | 104 | 2010 |
Increased expression of cholesterol 24S‐hydroxylase results in disruption of glial glutamate transporter EAAT2 association with lipid rafts: a potential role in Alzheimer’s disease G Tian, Q Kong, L Lai, A Ray‐Chaudhury, CG Lin Journal of neurochemistry 113 (4), 978-989, 2010 | 101 | 2010 |
Increased glial glutamate transporter EAAT2 expression reduces epileptogenic processes following pilocarpine-induced status epilepticus Q Kong, K Takahashi, D Schulte, N Stouffer, Y Lin, CLG Lin Neurobiology of disease 47 (2), 145-154, 2012 | 94 | 2012 |
Interleukin‐1β enhances nucleotide‐induced and α‐secretase‐dependent amyloid precursor protein processing in rat primary cortical neurons via up‐regulation of the P2Y2 receptor Q Kong, TS Peterson, O Baker, E Stanley, J Camden, CI Seye, L Erb, ... Journal of neurochemistry 109 (5), 1300-1310, 2009 | 80 | 2009 |
P2X7 nucleotide receptors mediate caspase-8/9/3-dependent apoptosis in rat primary cortical neurons Q Kong, M Wang, Z Liao, JM Camden, S Yu, A Simonyi, GY Sun, ... Purinergic signalling 1, 337-347, 2005 | 72 | 2005 |
Structure–activity relationship study of pyridazine derivatives as glutamate transporter EAAT2 activators X Xing, LC Chang, Q Kong, CK Colton, L Lai, MA Glicksman, CLG Lin, ... Bioorganic & medicinal chemistry letters 21 (19), 5774-5777, 2011 | 51 | 2011 |
RNA oxidation: a contributing factor or an epiphenomenon in the process of neurodegeneration Q Kong, X Shan, Y Chang, H Tashiro, CLG Lin Free radical research 42 (9), 773-777, 2008 | 31 | 2008 |
The importance of preclinical trial timing–a potential reason for the disconnect between mouse studies and human clinical trials in ALS Q Kong, S Carothers, Y Chang, CLG Lin CNS neuroscience & therapeutics 18 (9), 791, 2012 | 20 | 2012 |