The CDK inhibitor CR8 acts as a molecular glue degrader that depletes cyclin K M Słabicki, Z Kozicka, G Petzold, YD Li, M Manojkumar, RD Bunker, ... Nature 585 (7824), 293-297, 2020 | 270 | 2020 |
Small-molecule-induced polymerization triggers degradation of BCL6 M Słabicki, H Yoon, J Koeppel, L Nitsch, SS Roy Burman, C Di Genua, ... Nature 588 (7836), 164-168, 2020 | 169 | 2020 |
Selection of oncogenic mutant clones in normal human skin varies with body site JC Fowler, C King, C Bryant, MWJ Hall, R Sood, SH Ong, E Earp, ... Cancer discovery 11 (2), 340-361, 2021 | 78 | 2021 |
Prediction of prime editing insertion efficiencies using sequence features and DNA repair determinants J Koeppel, J Weller, EM Peets, A Pallaseni, I Kuzmin, U Raudvere, ... Nature Biotechnology 41 (10), 1446-1456, 2023 | 43* | 2023 |
Loss of neurological disease HSAN-I-associated gene SPTLC2 impairs CD8+ T cell responses to infection by inhibiting T cell metabolic fitness J Wu, S Ma, R Sandhoff, Y Ming, A Hotz-Wagenblatt, V Timmerman, ... Immunity 50 (5), 1218-1231. e5, 2019 | 36 | 2019 |
Predicting base editing outcomes using position-specific sequence determinants A Pallaseni, EM Peets, J Koeppel, J Weller, T Vanderstichele, UL Ho, ... Nucleic Acids Research 50 (6), 3551-3564, 2022 | 24 | 2022 |
Degradation of GSPT1 causes TP53-independent cell death in leukemia while sparing normal hematopoietic stem cells RS Sellar, AS Sperling, M Słabicki, JA Gasser, ME McConkey, ... The Journal of Clinical Investigation 132 (16), 2022 | 22 | 2022 |
Selection of oncogenic mutant clones in normal human skin varies with body site. Cancer Discov. 2021; 11: 340–361. doi: 10.1158/2159-8290 JC Fowler, C King, C Bryant, MWJ Hall, R Sood, SH Ong, E Earp, ... CD-20-1092.[Europe PMC free article][Abstract][CrossRef][Google Scholar], 0 | 11 | |
BTBBCL6 dimers as building blocks for reversible drug-induced protein oligomerization L Nitsch, P Jensen, H Yoon, J Koeppel, SSR Burman, ES Fischer, ... Cell Reports Methods 2 (4), 2022 | 9 | 2022 |
Randomizing the human genome by engineering recombination between repeat elements J Koeppel, R Ferreira, T Vanderstichele, LM Riedmayr, EM Peets, ... bioRxiv, 2024.01. 22.576745, 2024 | 3 | 2024 |
Multiplex generation and single cell analysis of structural variants in a mammalian genome S Pinglay, JB Lalanne, RM Daza, J Koeppel, X Li, DS Lee, J Shendure bioRxiv, 2024 | 2 | 2024 |
Misexpression of inactive genes in whole blood is associated with nearby rare structural variants T Vanderstichele, KL Burnham, N de Klein, M Tardaguila, B Howell, ... bioRxiv, 2023.11. 17.567537, 2023 | 1 | 2023 |
Predicting Mutations Generated by Cas9, Base Editing, and Prime Editing in Mammalian Cells J Weller, A Pallaseni, J Koeppel, L Parts The CRISPR Journal 6 (4), 325-338, 2023 | | 2023 |
Chemically inducible polypeptide polymerization B Ebert, M Slabicki, ES Fischer, H Yoon, J Koeppel US Patent App. 17/750,061, 2022 | | 2022 |