Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression NR Wray, S Ripke, M Mattheisen, M Trzaskowski, EM Byrne, A Abdellaoui, ... Nature genetics 50 (5), 668-681, 2018 | 2054 | 2018 |
Sparse whole-genome sequencing identifies two loci for major depressive disorder Nature 523 (7562), 588-591, 2015 | 614 | 2015 |
Reevaluation of SNP heritability in complex human traits D Speed, N Cai, Ucleb Consortium, MR Johnson, S Nejentsev, ... Nature genetics 49 (7), 986-992, 2017 | 397 | 2017 |
The polygenic and monogenic basis of blood traits and diseases D Vuckovic, EL Bao, P Akbari, CA Lareau, A Mousas, T Jiang, MH Chen, ... Cell 182 (5), 1214-1231. e11, 2020 | 281 | 2020 |
Molecular signatures of major depression N Cai, S Chang, Y Li, Q Li, J Hu, J Liang, L Song, W Kretzschmar, X Gan, ... Current Biology 25 (9), 1146-1156, 2015 | 239 | 2015 |
Minimal phenotyping yields genome-wide association signals of low specificity for major depression N Cai, JA Revez, MJ Adams, TFM Andlauer, G Breen, EM Byrne, ... Nature Genetics 52 (4), 437-447, 2020 | 194* | 2020 |
The genetics of the mood disorder spectrum: genome-wide association analyses of more than 185,000 cases and 439,000 controls JRI Coleman, HA Gaspar, J Bryois, EM Byrne, AJ Forstner, PA Holmans, ... Biological psychiatry 88 (2), 169-184, 2020 | 110 | 2020 |
Genome-wide association of multiple complex traits in outbred mice by ultra-low-coverage sequencing J Nicod, RW Davies, N Cai, C Hassett, L Goodstadt, C Cosgrove, BK Yee, ... Nature genetics 48 (8), 912-918, 2016 | 110 | 2016 |
Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium DM Howard, MJ Adams, WD Hill, TK Clarke, MJ Adams, TK Clarke, ... Nature Communications 11 (1), 2301, 2020 | 108 | 2020 |
Does childhood trauma moderate polygenic risk for depression? A meta-analysis of 5765 subjects from the psychiatric genomics consortium WJ Peyrot, S Van der Auwera, Y Milaneschi, CV Dolan, PAF Madden, ... Biological psychiatry 84 (2), 138-147, 2018 | 93 | 2018 |
Reviewing the genetics of heterogeneity in depression: operationalizations, manifestations and etiologies N Cai, KW Choi, EI Fried Human molecular genetics 29 (R1), R10-R18, 2020 | 89 | 2020 |
Genetic control over mtDNA and its relationship to major depressive disorder N Cai, Y Li, S Chang, J Liang, C Lin, X Zhang, L Liang, J Hu, W Chan, ... Current Biology 25 (24), 3170-3177, 2015 | 75 | 2015 |
Molecular genetic analysis subdivided by adversity exposure suggests etiologic heterogeneity in major depression RE Peterson, N Cai, AW Dahl, TB Bigdeli, AC Edwards, BT Webb, ... American Journal of Psychiatry 175 (6), 545-554, 2018 | 65 | 2018 |
Identification of rare and common regulatory variants in pluripotent cells using population-scale transcriptomics MJ Bonder, C Smail, MJ Gloudemans, L Frésard, D Jakubosky, ... Nature genetics 53 (3), 313-321, 2021 | 51* | 2021 |
The genetic architecture of depression in individuals of East Asian ancestry: a genome-wide association study O Giannakopoulou, K Lin, X Meng, MH Su, PH Kuo, RE Peterson, ... JAMA psychiatry 78 (11), 1258-1269, 2021 | 49 | 2021 |
The genetic architecture of major depressive disorder in Han Chinese women RE Peterson, N Cai, TB Bigdeli, Y Li, M Reimers, A Nikulova, BT Webb, ... JAMA psychiatry 74 (2), 162-168, 2017 | 48 | 2017 |
A robust method uncovers significant context-specific heritability in diverse complex traits A Dahl, K Nguyen, N Cai, MJ Gandal, J Flint, N Zaitlen The American Journal of Human Genetics 106 (1), 71-91, 2020 | 42* | 2020 |
RETRACTED ARTICLE: 11,670 whole-genome sequences representative of the Han Chinese population from the CONVERGE project N Cai, TB Bigdeli, WW Kretzschmar, Y Li, J Liang, J Hu, RE Peterson, ... Scientific data 4 (1), 1-14, 2017 | 42 | 2017 |
Reverse GWAS: Using genetics to identify and model phenotypic subtypes A Dahl, N Cai, A Ko, M Laakso, P Pajukanta, J Flint, N Zaitlen PLoS genetics 15 (4), e1008009, 2019 | 41 | 2019 |
Cross-trait assortative mating is widespread and inflates genetic correlation estimates R Border, G Athanasiadis, A Buil, AJ Schork, N Cai, AI Young, T Werge, ... Science 378 (6621), 754-761, 2022 | 29 | 2022 |