Smad2 and Smad3 positively and negatively regulate TGFβ-dependent transcription through the forkhead DNA-binding protein FAST2 E Labbé, C Silvestri, PA Hoodless, JL Wrana, L Attisano Molecular cell 2 (1), 109-120, 1998 | 636 | 1998 |
The endocannabinoid system in energy homeostasis and the etiopathology of metabolic disorders C Silvestri, V Di Marzo Cell metabolism 17 (4), 475-490, 2013 | 598 | 2013 |
Foxh1 is essential for development of the anterior heart field I von Both, C Silvestri, T Erdemir, H Lickert, JR Walls, RM Henkelman, ... Developmental cell 7 (3), 331-345, 2004 | 233 | 2004 |
Endoglin increases eNOS expression by modulating Smad2 protein levels and Smad2‐dependent TGF‐β signaling JF Santibanez, A Letamendia, F Perez‐Barriocanal, C Silvestri, M Saura, ... Journal of cellular physiology 210 (2), 456-468, 2007 | 169 | 2007 |
Obesity-driven synaptic remodeling affects endocannabinoid control of orexinergic neurons L Cristino, G Busetto, R Imperatore, I Ferrandino, L Palomba, C Silvestri, ... Proceedings of the National Academy of Sciences 110 (24), E2229-E2238, 2013 | 149 | 2013 |
The transcriptional role of Smads and FAST (FoxH1) in TGFβ and activin signalling L Attisano, C Silvestri, L Izzi, E Labbé Molecular and cellular endocrinology 180 (1-2), 3-11, 2001 | 145 | 2001 |
Lifestyle and metabolic syndrome: contribution of the endocannabinoidome V Di Marzo, C Silvestri Nutrients 11 (8), 1956, 2019 | 130 | 2019 |
The cannabinoid Δ9-tetrahydrocannabivarin (THCV) ameliorates insulin sensitivity in two mouse models of obesity ET Wargent, MS Zaibi, C Silvestri, DC Hislop, CJ Stocker, CG Stott, ... Nutrition & diabetes 3 (5), e68-e68, 2013 | 123 | 2013 |
Germ-free mice exhibit profound gut microbiota-dependent alterations of intestinal endocannabinoidome signaling C Manca, B Boubertakh, N Leblanc, T Deschênes, S Lacroix, C Martin, ... Journal of lipid research 61 (1), 70-85, 2020 | 112 | 2020 |
Peripheral effects of the endocannabinoid system in energy homeostasis: adipose tissue, liver and skeletal muscle C Silvestri, A Ligresti, V Di Marzo Reviews in Endocrine and Metabolic Disorders 12 (3), 153-162, 2011 | 103 | 2011 |
Two non-psychoactive cannabinoids reduce intracellular lipid levels and inhibit hepatosteatosis C Silvestri, D Paris, A Martella, D Melck, I Guadagnino, M Cawthorne, ... Journal of hepatology 62 (6), 1382-1390, 2015 | 101 | 2015 |
The endocannabinoid 2-AG controls skeletal muscle cell differentiation via CB1 receptor-dependent inhibition of Kv7 channels FA Iannotti, C Silvestri, E Mazzarella, A Martella, D Calvigioni, F Piscitelli, ... Proceedings of the National Academy of Sciences 111 (24), E2472-E2481, 2014 | 97 | 2014 |
Second generation CB1 receptor blockers and other inhibitors of peripheral endocannabinoid overactivity and the rationale of their use against metabolic disorders C Silvestri, V Di Marzo Expert opinion on investigational drugs 21 (9), 1309-1322, 2012 | 93 | 2012 |
Chronic treatment with krill powder reduces plasma triglyceride and anandamide levels in mildly obese men K Berge, F Piscitelli, N Hoem, C Silvestri, I Meyer, S Banni, V Di Marzo Lipids in health and disease 12, 1-8, 2013 | 91 | 2013 |
The expanded endocannabinoid system/endocannabinoidome as a potential target for treating diabetes mellitus A Veilleux, V Di Marzo, C Silvestri Current Diabetes Reports 19, 1-12, 2019 | 84 | 2019 |
Bisphenol A induces fatty liver by an endocannabinoid-mediated positive feedback loop A Martella, C Silvestri, F Maradonna, G Gioacchini, M Allara, G Radaelli, ... Endocrinology 157 (5), 1751-1763, 2016 | 83 | 2016 |
CB1 cannabinoid receptors couple to focal adhesion kinase to control insulin release K Malenczyk, M Jazurek, E Keimpema, C Silvestri, J Janikiewicz, ... Journal of Biological Chemistry 288 (45), 32685-32699, 2013 | 81 | 2013 |
Endocannabinoid regulation in white and brown adipose tissue following thermogenic activation LM Krott, F Piscitelli, M Heine, S Borrino, L Scheja, C Silvestri, J Heeren, ... Journal of lipid research 57 (3), 464-473, 2016 | 75 | 2016 |
Genome-wide identification of Smad/Foxh1 targets reveals a role for Foxh1 in retinoic acid regulation and forebrain development C Silvestri, M Narimatsu, I von Both, Y Liu, NBJ Tan, L Izzi, P McCaffery, ... Developmental cell 14 (3), 411-423, 2008 | 71 | 2008 |
Negative regulation of leptin-induced reactive oxygen species (ROS) formation by cannabinoid CB1 receptor activation in hypothalamic neurons L Palomba, C Silvestri, R Imperatore, G Morello, F Piscitelli, A Martella, ... Journal of Biological Chemistry 290 (22), 13669-13677, 2015 | 63 | 2015 |