Big data in basic and translational cancer research P Jiang, S Sinha, K Aldape, S Hannenhalli, C Sahinalp, E Ruppin Nature Reviews Cancer 22 (11), 625-639, 2022 | 116 | 2022 |
In vitro and in vivo identification of clinically approved drugs that modify ACE2 expression S Sinha, K Cheng, AA Schäffer, K Aldape, E Schiff, E Ruppin Molecular systems biology 16 (7), e9628, 2020 | 75* | 2020 |
Synthetic lethality-mediated precision oncology via the tumor transcriptome JS Lee, NU Nair, G Dinstag, L Chapman, Y Chung, K Wang, S Sinha, ... Cell 184 (9), 2487-2502. e13, 2021 | 73 | 2021 |
Identification of drugs associated with reduced severity of COVID-19–a case-control study in a large population A Israel, AA Schäffer, A Cicurel, K Cheng, S Sinha, E Schiff, I Feldhamer, ... Elife 10, e68165, 2021 | 63* | 2021 |
A systematic genome-wide mapping of oncogenic mutation selection during CRISPR-Cas9 genome editing S Sinha, K Barbosa, K Cheng, MDM Leiserson, P Jain, A Deshpande, ... Nature communications 12 (1), 6512, 2021 | 49* | 2021 |
AXL and error-prone DNA replication confer drug resistance and offer strategies to treat EGFR-mutant lung cancer A Noronha, N Belugali Nataraj, JS Lee, B Zhitomirsky, Y Oren, S Oster, ... Cancer discovery 12 (11), 2666-2683, 2022 | 47 | 2022 |
A Division of Labor between YAP and TAZ in Non–Small Cell Lung Cancer M Shreberk-Shaked, B Dassa, S Sinha, S Di Agostino, I Azuri, ... Cancer research 80 (19), 4145-4157, 2020 | 42 | 2020 |
Higher prevalence of homologous recombination deficiency in tumors from African Americans versus European Americans S Sinha, KA Mitchell, A Zingone, E Bowman, N Sinha, AA Schäffer, ... Nature Cancer 1 (1), 112-121, 2020 | 39 | 2020 |
Genome‐scale metabolic modeling reveals SARS‐CoV‐2‐induced metabolic changes and antiviral targets K Cheng, L Martin‐Sancho, LR Pal, Y Pu, L Riva, X Yin, S Sinha, NU Nair, ... Molecular systems biology 17 (11), e10260, 2021 | 30* | 2021 |
Recurrent PTPRT/JAK2 mutations in lung adenocarcinoma among African Americans KA Mitchell, N Nichols, W Tang, J Walling, H Stevenson, M Pineda, ... Nature communications 10 (1), 5735, 2019 | 27 | 2019 |
Immune determinants of the association between tumor mutational burden and immunotherapy response across cancer types N Sinha, S Sinha, C Valero, AA Schäffer, K Aldape, K Litchfield, TA Chan, ... Cancer research 82 (11), 2076-2083, 2022 | 24 | 2022 |
Whole-exome profiling of NSCLC among African Americans RF Arauz, JS Byun, M Tandon, S Sinha, S Kuhn, S Taylor, A Zingone, ... Journal of Thoracic Oncology 15 (12), 1880-1892, 2020 | 22 | 2020 |
Dysregulation of HNF1B/Clusterin axis enhances disease progression in a highly aggressive subset of pancreatic cancer patients S Yang, W Tang, A Azizian, J Gaedcke, P Ströbel, L Wang, H Cawley, ... Carcinogenesis 43 (12), 1198-1210, 2022 | 16 | 2022 |
The GPCR–Gαs–PKA signaling axis promotes T cell dysfunction and cancer immunotherapy failure VH Wu, BS Yung, F Faraji, R Saddawi-Konefka, Z Wang, AT Wenzel, ... Nature immunology 24 (8), 1318-1330, 2023 | 14 | 2023 |
MCP-1/CCR2 axis inhibition sensitizes the brain microenvironment against melanoma brain metastasis progression S Pozzi, A Scomparin, D Ben-Shushan, E Yeini, P Ofek, AD Nahmad, ... JCI insight 7 (17), 2022 | 14 | 2022 |
Clinically oriented prediction of patient response to targeted and immunotherapies from the tumor transcriptome G Dinstag, ED Shulman, E Elis, DS Ben-Zvi, O Tirosh, E Maimon, ... Med 4 (1), 15-30. e8, 2023 | 13 | 2023 |
The landscape of receptor-mediated precision cancer combination therapy via a single-cell perspective S Ahmadi, P Sukprasert, R Vegesna, S Sinha, F Schischlik, N Artzi, ... Nature communications 13 (1), 1613, 2022 | 13 | 2022 |
A comprehensive map of alternative polyadenylation in African American and European American lung cancer patients A Zingone, S Sinha, M Ante, C Nguyen, D Daujotyte, ED Bowman, ... Nature communications 12 (1), 5605, 2021 | 12 | 2021 |
Membrane-tethered mucin 1 is stimulated by interferon and virus infection in multiple cell types and inhibits influenza a virus infection in human airway epithelium E Iverson, K Griswold, D Song, TB Gagliardi, K Hamidzadeh, M Kesimer, ... MBio 13 (4), e01055-22, 2022 | 10* | 2022 |
Prediction of cancer treatment response from histopathology images through imputed transcriptomics DT Hoang, G Dinstag, LC Hermida, DS Ben-Zvi, E Elis, K Caley, ... Research Square, 2023 | 9* | 2023 |