| BNT162b vaccines protect rhesus macaques from SARS-CoV-2 AB Vogel, I Kanevsky, Y Che, KA Swanson, A Muik, M Vormehr, LM Kranz, ... Nature 592 (7853), 283-289, 2021 | 595 | 2021 |
| Chemical and computational methods for the characterization of covalent reactive groups for the prospective design of irreversible inhibitors ME Flanagan, JA Abramite, DP Anderson, A Aulabaugh, UP Dahal, ... Journal of medicinal chemistry 57 (23), 10072-10079, 2014 | 287 | 2014 |
| Thermodynamic analysis of water molecules at the surface of proteins and applications to binding site prediction and characterization T Beuming, Y Che, R Abel, B Kim, V Shanmugasundaram, W Sherman Proteins: Structure, Function, and Bioinformatics 80 (3), 871-883, 2012 | 166 | 2012 |
| A prefusion SARS-CoV-2 spike RNA vaccine is highly immunogenic and prevents lung infection in non-human primates AB Vogel, I Kanevsky, Y Che, KA Swanson, A Muik, M Vormehr, LM Kranz, ... BioRxiv, 2020.09. 08.280818, 2020 | 137 | 2020 |
| Design of a Janus Kinase 3 (JAK3) Specific Inhibitor 1-((2S,5R)-5-((7H-Pyrrolo[2,3-d]pyrimidin-4-yl)amino)-2-methylpiperidin-1-yl)prop-2-en-1-one (PF … A Thorarensen, ME Dowty, ME Banker, B Juba, J Jussif, T Lin, F Vincent, ... Journal of medicinal chemistry 60 (5), 1971-1993, 2017 | 136 | 2017 |
| Pyridone methylsulfone hydroxamate LpxC inhibitors for the treatment of serious gram-negative infections JI Montgomery, MF Brown, U Reilly, LM Price, JA Abramite, J Arcari, ... Journal of medicinal chemistry 55 (4), 1662-1670, 2012 | 113 | 2012 |
| Potent inhibitors of LpxC for the treatment of Gram-negative infections MF Brown, U Reilly, JA Abramite, JT Arcari, R Oliver, RA Barham, Y Che, ... Journal of medicinal chemistry 55 (2), 914-923, 2012 | 111 | 2012 |
| Development of small molecules designed to modulate protein–protein interactions Y Che, BR Brooks, GR Marshall Journal of computer-aided molecular design 20, 109-130, 2006 | 86 | 2006 |
| Structural basis for chemokine receptor CCR6 activation by the endogenous protein ligand CCL20 DJ Wasilko, ZL Johnson, M Ammirati, Y Che, MC Griffor, S Han, H Wu Nature communications 11 (1), 3031, 2020 | 85 | 2020 |
| Discovery of a highly selective glycogen synthase kinase‐3 inhibitor (PF‐04802367) that modulates tau phosphorylation in the brain: Translation for PET neuroimaging SH Liang, JM Chen, MD Normandin, JS Chang, GC Chang, CK Taylor, ... Angewandte Chemie International Edition 55 (33), 9601-9605, 2016 | 81 | 2016 |
| Engineering cyclic tetrapeptides containing chimeric amino acids as preferred reverse-turn scaffolds Y Che, GR Marshall Journal of medicinal chemistry 49 (1), 111-124, 2006 | 75 | 2006 |
| Impact of Cis‐proline analogs on peptide conformation Y Che, GR Marshall Biopolymers: Original Research on Biomolecules 81 (5), 392-406, 2006 | 72 | 2006 |
| Inducing protein-protein interactions with molecular glues Y Che, AM Gilbert, V Shanmugasundaram, MC Noe Bioorganic & Medicinal Chemistry Letters 28 (15), 2585-2592, 2018 | 71 | 2018 |
| Snapshots and ensembles of BTK and cIAP1 protein degrader ternary complexes J Schiemer, R Horst, Y Meng, JI Montgomery, Y Xu, X Feng, K Borzilleri, ... Nature Chemical Biology 17 (2), 152-160, 2021 | 70 | 2021 |
| Siderophore receptor-mediated uptake of lactivicin analogues in gram-negative bacteria J Starr, MF Brown, L Aschenbrenner, N Caspers, Y Che, ... Journal of medicinal chemistry 57 (9), 3845-3855, 2014 | 67 | 2014 |
| Prefusion structure of human cytomegalovirus glycoprotein B and structural basis for membrane fusion Y Liu, KP Heim, Y Che, X Chi, X Qiu, S Han, PR Dormitzer, X Yang Science Advances 7 (10), eabf3178, 2021 | 65 | 2021 |
| Cryo-EM structures of the human glutamine transporter SLC1A5 (ASCT2) in the outward-facing conformation X Yu, O Plotnikova, PD Bonin, TA Subashi, TJ McLellan, D Dumlao, ... Elife 8, e48120, 2019 | 61 | 2019 |
| Non-traditional antibacterial screening approaches for the identification of novel inhibitors of the glyoxylate shunt in gram-negative pathogens KC Fahnoe, ME Flanagan, G Gibson, V Shanmugasundaram, Y Che, ... PloS one 7 (12), e51732, 2012 | 61 | 2012 |
| Impact of azaproline on peptide conformation Y Che, GR Marshall The Journal of Organic Chemistry 69 (26), 9030-9042, 2004 | 61 | 2004 |
| Pyrrolo [2, 3-d] pyrimidinyl, pyrrolo [2, 3-b] pyrazinyl and pyrrolo [2, 3-d] pyridinyl acrylamides A Thorarensen, MF Brown, A Casimiro-Garcia, CHE Ye, JW Coe, ... US Patent 9,617,258, 2017 | 51 | 2017 |
