Mechanisms of RecQ helicases in pathways of DNA metabolism and maintenance of genomic stability S Sharma, KM Doherty, RM Brosh Jr Biochemical Journal 398 (3), 319-337, 2006 | 286 | 2006 |
The FANCJ/MutLα interaction is required for correction of the cross‐link response in FA‐J cells M Peng, R Litman, J Xie, S Sharma, RM Brosh Jr, SB Cantor The EMBO journal 26 (13), 3238-3249, 2007 | 206 | 2007 |
Biochemical Analysis of the DNA Unwinding and Strand Annealing Activities Catalyzed by Human RECQ1*[boxs] S Sharma, JA Sommers, S Choudhary, JK Faulkner, S Cui, L Andreoli, ... Journal of Biological Chemistry 280 (30), 28072-28084, 2005 | 182 | 2005 |
WRN helicase and FEN-1 form a complex upon replication arrest and together process branchmigrating DNA structures associated with the replication fork S Sharma, M Otterlei, JA Sommers, HC Driscoll, GL Dianov, HI Kao, ... Molecular biology of the cell 15 (2), 734-750, 2004 | 155 | 2004 |
Analysis of the DNA Substrate Specificity of the Human BACH1 HelicaseAssociated with BreastCancer R Gupta, S Sharma, JA Sommers, Z Jin, SB Cantor, RM Brosh Journal of Biological Chemistry 280 (27), 25450-25460, 2005 | 148 | 2005 |
Long noncoding RNA PURPL suppresses basal p53 levels and promotes tumorigenicity in colorectal cancer XL Li, M Subramanian, MF Jones, R Chaudhary, DK Singh, X Zong, ... Cell reports 20 (10), 2408-2423, 2017 | 141 | 2017 |
RECQL, a member of the RecQ family of DNA helicases, suppresses chromosomal instability S Sharma, DJ Stumpo, AS Balajee, CB Bock, PM Lansdorp, RM Brosh Jr, ... Molecular and cellular biology 27 (5), 1784-1794, 2007 | 132 | 2007 |
FANCJ (BACH1) helicase forms DNA damage inducible foci with replication protein A and interacts physically and functionally with the single-stranded DNA-binding protein R Gupta, S Sharma, JA Sommers, MK Kenny, SB Cantor, RM Brosh Jr Blood, The Journal of the American Society of Hematology 110 (7), 2390-2398, 2007 | 124 | 2007 |
Stimulation of flap endonuclease-1 by the Bloom's syndrome protein S Sharma, JA Sommers, L Wu, VA Bohr, ID Hickson, RM Brosh Journal of Biological Chemistry 279 (11), 9847-9856, 2004 | 122 | 2004 |
Human RECQ1 is a DNA damage responsive protein required for genotoxic stress resistance and suppression of sister chromatid exchanges S Sharma, RM Brosh Jr PloS one 2 (12), e1297, 2007 | 121 | 2007 |
A p21-ZEB1 complex inhibits epithelial-mesenchymal transition through the microRNA 183-96-182 cluster XL Li, T Hara, Y Choi, M Subramanian, P Francis, S Bilke, RL Walker, ... Molecular and cellular biology 34 (3), 533-550, 2014 | 114 | 2014 |
RECQ1 Helicase Interacts with Human Mismatch Repair Factors That Regulate Genetic Recombination*[boxs] KM Doherty, S Sharma, LA Uzdilla, TM Wilson, S Cui, A Vindigni, ... Journal of Biological Chemistry 280 (30), 28085-28094, 2005 | 106 | 2005 |
Interaction between the helicases genetically linked to Fanconi anemia group J and Bloom's syndrome AN Suhasini, NA Rawtani, Y Wu, JA Sommers, S Sharma, G Mosedale, ... The EMBO journal 30 (4), 692-705, 2011 | 99 | 2011 |
A mutant p53/let-7i-axis-regulated gene network drives cell migration, invasion and metastasis M Subramanian, P Francis, S Bilke, XL Li, T Hara, X Lu, MF Jones, ... Oncogene 34 (9), 1094-1104, 2015 | 92 | 2015 |
DNA helicases as targets for anti-cancer drugs S Sharma, KM Doherty, RM Brosh Jr Current Medicinal Chemistry-Anti-Cancer Agents 5 (3), 183-199, 2005 | 80 | 2005 |
Genetic regulation of OAS1 nonsense-mediated decay underlies association with COVID-19 hospitalization in patients of European and African ancestries AR Banday, ML Stanifer, O Florez-Vargas, OO Onabajo, BW Papenberg, ... Nature genetics 54 (8), 1103-1116, 2022 | 74 | 2022 |
The interaction site of Flap Endonuclease-1 with WRN helicase suggests a coordination of WRN and PCNA S Sharma, JA Sommers, RK Gary, E Friedrich-Heineken, U Hübscher, ... Nucleic acids research 33 (21), 6769-6781, 2005 | 73 | 2005 |
Human RECQ1 interacts with Ku70/80 and modulates DNA end-joining of double-strand breaks S Parvathaneni, A Stortchevoi, JA Sommers, RM Brosh Jr, S Sharma PLoS One 8 (5), e62481, 2013 | 67 | 2013 |
The exonucleolytic and endonucleolytic cleavage activities of human exonuclease 1 are stimulated by an interaction with the carboxyl-terminal region of the Werner syndrome protein S Sharma, JA Sommers, HC Driscoll, L Uzdilla, TM Wilson, RM Brosh Journal of Biological Chemistry 278 (26), 23487-23496, 2003 | 66 | 2003 |
p53 modulates RPA-dependent and RPA-independent WRN helicase activity JA Sommers, S Sharma, KM Doherty, P Karmakar, Q Yang, MK Kenny, ... Cancer research 65 (4), 1223-1233, 2005 | 64 | 2005 |