| Intranasal administration of plasmid DNA nanoparticles yields successful transfection and expression of a reporter protein in rat brain BT Harmon, AE Aly, L Padegimas, O Sesenoglu-Laird, MJ Cooper, ... Gene therapy 21 (5), 514-521, 2014 | 58 | 2014 |
| Intranasal gene delivery for treating Parkinson’s disease: overcoming the blood–brain barrier AEE Aly, BL Waszczak Expert opinion on drug delivery 12 (12), 1923-1941, 2015 | 56 | 2015 |
| Mutant huntingtin is cleared from the brain via active mechanisms in Huntington disease NS Caron, R Banos, C Yanick, AE Aly, LM Byrne, ED Smith, Y Xie, ... Journal of Neuroscience 41 (4), 780-796, 2021 | 55 | 2021 |
| Intranasal delivery of pGDNF DNA nanoparticles provides neuroprotection in the rat 6-hydroxydopamine model of Parkinson’s disease AEE Aly, BT Harmon, L Padegimas, O Sesenoglu-Laird, MJ Cooper, ... Molecular Neurobiology 56, 688-701, 2019 | 53 | 2019 |
| Intranasal delivery of hGDNF plasmid DNA nanoparticles results in long-term and widespread transfection of perivascular cells in rat brain AEE Aly, B Harmon, L Padegimas, O Sesenoglu-Laird, MJ Cooper, ... Nanomedicine: Nanotechnology, Biology and Medicine 16, 20-33, 2019 | 31 | 2019 |
| DAPK1 promotes extrasynaptic GluN2B phosphorylation and striatal spine instability in the YAC128 mouse model of Huntington disease ME Schmidt, NS Caron, AE Aly, FL Lemarié, L Dal Cengio, Y Ko, N Lazic, ... Frontiers in Cellular Neuroscience 14, 590569, 2020 | 16 | 2020 |
| Cerebrospinal fluid mutant huntingtin is a biomarker for huntingtin lowering in the striatum of Huntington disease mice NS Caron, R Banos, AE Aly, Y Xie, S Ko, N Potluri, C Anderson, HF Black, ... Neurobiology of Disease 166, 105652, 2022 | 15 | 2022 |
| Cerebrospinal fluid biomarkers for assessing Huntington disease onset and severity NS Caron, AS Haqqani, A Sandhu, AE Aly, H Findlay Black, JN Bone, ... Brain Communications 4 (6), fcac309, 2022 | 15 | 2022 |
| Focused ultrasound enhances transgene expression of intranasal hGDNF DNA nanoparticles in the sonicated brain regions AEE Aly, T Sun, Y Zhang, Z Li, M Kyada, Q Ma, L Padegimas, ... Journal of Controlled Release 358, 498-509, 2023 | 4 | 2023 |
| Intranasal GDNF for Parkinson's disease: Next steps in preclinical development B Lee Waszczak, L Wachtman, GC Newsome, A Aly, N Silva, ... The FASEB Journal 27, 1177.10-1177.10, 2013 | 4 | 2013 |
| Delivery of mutant huntingtin-lowering antisense oligonucleotides to the brain by intranasally administered apolipoprotein AI nanodisks AEE Aly, NS Caron, HF Black, ME Schmidt, C Anderson, S Ko, ... Journal of Controlled Release 360, 913-927, 2023 | 3 | 2023 |
| Intranasal Delivery of hGDNF Nanoparticles Results in GDNF Expression Throughout Rat Brain and Provides Neuroprotection in the Rat 6-Hydroxydopamine Model of Parkinson's Disease AEE Aly, BT Harmon, K Dines, O Sesenoglu-Laird, L Padegimas, ... CELL TRANSPLANTATION 23 (6), 762-763, 2014 | 3 | 2014 |
| Systemic delivery of mutant huntingtin lowering antisense oligonucleotides to the brain using apolipoprotein AI nanodisks for Huntington disease NS Caron, AEE Aly, HF Black, DDO Martin, ME Schmidt, S Ko, ... Journal of Controlled Release 367, 27-44, 2024 | 2 | 2024 |
| Widespread expression of GDNF throughout rat brain after intranasal delivery of hGDNF plasmid nanoparticles AEE Aly, BT Harmon, P Shah, O Sesenoglu-Laird, L Padegimas, ... CELL TRANSPLANTATION 24 (4), 752-753, 2015 | 2 | 2015 |
| Intranasal delivery of pGDNF nanoparticles provides neuroprotection in the rat 6‐hydroxydopamine model of Parkinson's disease BT Harmon, A Aly, MJ Cooper, K Dines, L Padegimas, BL Waszczak The FASEB Journal 27, 662.12-662.12, 2013 | 2 | 2013 |
| 5th International Symposium on Focused Ultrasound M Zaaroor, A Sinai, D Goldsher, A Eran, M Nassar, I Schlesinger, J Parker, ... Journal of Therapeutic Ultrasound 4 (1), 1-113, 2016 | 1 | 2016 |
| Expression of GDNF throughout rat brain after intranasal delivery of hGDNF plasmid nanoparticles A Aly, B Harmon, P Shah, O Sesenoglu‐Laird, L Padegimas, M Cooper, ... The FASEB Journal 29, 620.10, 2015 | 1 | 2015 |
| D16 Cerebrospinal fluid biomarkers for assessing Huntington disease onset and severity NS Caron, AS Haqqani, A Sandhu, AE Aly, HF Black, JN Bone, ... Journal of Neurology, Neurosurgery & Psychiatry 93 (Suppl 1), A25-A26, 2022 | | 2022 |
| Mutant Huntingtin Is Cleared fromthe Brain via Active Mechanisms R Banos, C Yanick, AE Aly, LM Byrne, ED Smith, Y Xie, SEP Smith, ... NEUROTHERAPEUTICS 17 (SUPPL 1), 38-39, 2020 | | 2020 |
| An Intranasal Gene Therapy for Parkinson's Disease and Enhancement by Focused Ultrasound (FUS) BL Waszczak, AEE Aly CELL TRANSPLANTATION 26 (4), 729-730, 2017 | | 2017 |
