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Karrthik Krishnamurthy
Karrthik Krishnamurthy
在 jefferson.edu 的电子邮件经过验证 - 首页
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Antisense Proline-Arginine RAN Dipeptides Linked to C9ORF72-ALS/FTD Form Toxic Nuclear Aggregates that Initiate In Vitro and In Vivo Neuronal Death
X Wen, W Tan, T Westergard, K Krishnamurthy, ...
Neuron 84 (6), 1213-1225, 2014
5822014
Astrocytes expressing ALS-linked mutant FUS induce motor neuron death through release of tumor necrosis factor-alpha
A Kia, K McAvoy, K Krishnamurthy, D Trotti, P Pasinelli
Glia 23298 (doi: 10.1002/glia.23298.), doi: 10.1002/glia.23298., 2018
1062018
Pur-alpha regulates cytoplasmic stress granule dynamics and ameliorates FUS toxicity
JG Daigle, K Krishnamurthy, N Ramesh, I Casci, J Monaghan, K McAvoy, ...
Acta neuropathologica 131, 605-620, 2016
652016
Synaptic dysfunction induced by glycine‐alanine dipeptides in C9orf72‐ALS/FTD is rescued by SV 2 replenishment
BK Jensen, MH Schuldi, K McAvoy, KA Russell, A Boehringer, BM Curran, ...
EMBO molecular medicine 12 (5), e10722, 2020
462020
Muscleblind acts as a modifier of FUS toxicity by modulating stress granule dynamics and SMN localization
I Casci, K Krishnamurthy, S Kour, V Tripathy, N Ramesh, EN Anderson, ...
Nature Communications 10 (1), 5583, 2019
312019
AMPA induced Ca2+ influx in motor neurons occurs through voltage gated Ca2+ channel and Ca2+ permeable AMPA receptor
DC Joshi, M Singh, K Krishnamurthy, PG Joshi, NB Joshi
Neurochemistry international 59 (6), 913-921, 2011
262011
AAV2-BDNF promotes respiratory axon plasticity and recovery of diaphragm function following spinal cord injury
BA Charsar, MA Brinton, K Locke, AY Chen, B Ghosh, MW Urban, ...
The FASEB Journal 33 (12), 13775, 2019
252019
A mouse model with widespread expression of the C9orf72-linked glycine–arginine dipeptide displays non-lethal ALS/FTD-like phenotypes
BM Verdone, ME Cicardi, X Wen, S Sriramoji, K Russell, SS Markandaiah, ...
Scientific reports 12 (1), 5644, 2022
202022
Synaptic dysfunction in ALS/FTD-Therapeutic strategies and novel biomarkers
K Krishnamurthy, P Pasinelli
Journal of neuroscience research 99 (6), 1499, 2021
82021
C9orf72 poly (PR) mediated neurodegeneration is associated with nucleolar stress
ME Cicardi, JH Hallgren, D Mawrie, K Krishnamurthy, SS Markandaiah, ...
Iscience 26 (9), 2023
52023
Real-time fluorescent measurement of synaptic functions in models of amyotrophic lateral sclerosis
K Krishnamurthy, D Trotti, P Pasinelli, B Jensen
JoVE (Journal of Visualized Experiments), e62813, 2021
52021
Emerging perspectives of synaptic biomarkers in ALS and FTD
K Krishnamurthy, RK Pradhan
Frontiers in Molecular Neuroscience 16, 1279999, 2024
42024
Depalmitoylation preferentially downregulates AMPA induced Ca2+ signaling and neurotoxicity in motor neurons
K Krishnamurthy, B Mehta, M Singh, BP Tewari, PG Joshi, NB Joshi
brain research 1529, 143-153, 2013
42013
Kapβ2 is a modifier of the C9orf72-linked glycine-arginine dipeptide neurotoxicity
ME Cicardi, V Kankate, S Sriramoji, K Krishnamurthy, SS Markandaiah, ...
bioRxiv, 2022.09. 30.510384, 2022
3*2022
IL-11 induces NLRP3 inflammasome activation, inflammatory cell migration to the CNS and neurotoxicity (P7-6.017)
K Krishnamurthy, M Seyedsadr, P Pasinelli, S Markovic-Plese
Neurology 102 (17_supplement_1), 6653, 2024
2024
Aberrant expression of the axon guidance cue netrin-1 by SOD1-ALS astrocytes contributes to motor neuron degeneration.
K Krishnamurthy, S Markandaiah, M Cicardi, B Ghosh, X Wen, K McAvoy, ...
GLIA 69, E194-E194, 2021
2021
Cultured cortical neurons transfected with genetically encoded calcium indicator GCaMP6m shows repetitive calcium spikes indicative of neuronal hyperexcitability induced by …
K Krishnamurthy, H Aaron, D Trotti, P Pasinelli
https://www.faseb.org/Publications-and-Resources/BioArt/About-BioArt/2020 …, 2020
2020
Fluorescence Imaging of Astrocytes Expressing a Toxic Protein, SOD1
K Krishnamurthy, SM Markandaiah, D Trotti, P Pasinelli
https://faseb.org/Publications-and-Resources/BioArt/Past-Winners/2019-BioArt …, 2019
2019
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