EditR: a method to quantify base editing from Sanger sequencing MG Kluesner, DA Nedveck, WS Lahr, JR Garbe, JE Abrahante, ... The CRISPR journal 1 (3), 239-250, 2018 | 425* | 2018 |
Highly efficient multiplex human T cell engineering without double-strand breaks using Cas9 base editors BR Webber, C Lonetree, MG Kluesner, MJ Johnson, EJ Pomeroy, ... Nature communications 10 (1), 5222, 2019 | 210 | 2019 |
A genetically engineered primary human natural killer cell platform for cancer immunotherapy EJ Pomeroy, JT Hunzeker, MG Kluesner, WS Lahr, BA Smeester, ... Molecular Therapy 28 (1), 52-63, 2020 | 158 | 2020 |
CRISPR-Cas9 cytidine and adenosine base editing of splice-sites mediates highly-efficient disruption of proteins in primary and immortalized cells MG Kluesner, WS Lahr, C Lonetree, BA Smeester, X Qiu, NJ Slipek, ... Nature communications 12 (1), 2437, 2021 | 88 | 2021 |
Highly multiplexed genome engineering using CRISPR/Cas9 gRNA arrays M Kurata, NK Wolf, WS Lahr, MT Weg, MG Kluesner, S Lee, K Hui, ... PLoS one 13 (9), e0198714, 2018 | 73 | 2018 |
MultiEditR: The first tool for the detection and quantification of RNA editing from Sanger sequencing demonstrates comparable fidelity to RNA-seq MG Kluesner, RN Tasakis, T Lerner, A Arnold, S Wüst, M Binder, ... Molecular Therapy-Nucleic Acids 25, 515-523, 2021 | 24* | 2021 |
Correction of Fanconi anemia mutations using digital genome engineering CJ Sipe, MG Kluesner, SP Bingea, WS Lahr, AA Andrew, M Wang, ... International journal of molecular sciences 23 (15), 8416, 2022 | 11 | 2022 |
Highly efficient multiplex human T cell engineering without double-strand breaks using Cas9 base editors. Nat. Commun. 10, 5222 BR Webber, CL Lonetree, MG Kluesner, MJ Johnson, EJ Pomeroy, ... | 9 | 2019 |
Signaling via a CD27-TRAF2-SHP-1 axis during naive T cell activation promotes memory-associated gene regulatory networks CA Jaeger-Ruckstuhl, Y Lo, E Fulton, OG Waltner, TB Shabaneh, S Simon, ... Immunity 57 (2), 287-302. e12, 2024 | 8 | 2024 |
Developing bottom-up induced pluripotent stem cell derived solid tumor models using precision genome editing technologies KL Becklin, GM Draper, RA Madden, MG Kluesner, T Koga, M Huang, ... The CRISPR journal 5 (4), 517-535, 2022 | 6 | 2022 |
C-to-U RNA editing: from computational detection to experimental validation T Lerner, M Kluesner, RN Tasakis, BS Moriarity, FN Papavasiliou, ... RNA Editing: Methods and Protocols, 51-67, 2021 | 5 | 2021 |
Precision Enhancement of CAR-NK Cells through Non-Viral Engineering and Highly Multiplexed Base Editing M Wang, JB Krueger, AK Gilkey, EM Stelljes, MG Kluesner, EJ Pomeroy, ... bioRxiv, 2024 | 3 | 2024 |
216 Multiplex base editing of NK cell to enhance cancer immunotherapy M Wang, M Kluesner, PC Vázquez, B Webber, B Moriarity Journal for ImmunoTherapy of Cancer 9 (Suppl 2), 2021 | 2 | 2021 |
Lymphohematopoietic engineering using cas9 base editors B Moriarity, B Webber, C Lonetree, M Diers, M Kluesner, L Walker, ... | 1 | 2019 |
1150 Non-virally engineered polyclonal gamma delta T cells exhibit potent anti-tumor activity in vivo J Bridge, J Kim, S Wenthe, J Krueger, B Wick, M Kluesner, A Crane, J Bell, ... Journal for ImmunoTherapy of Cancer 12 (Suppl 2), 2024 | | 2024 |
347 Highly multiplexed engineering of immune effector cells for advanced cancer therapies JG Skeate, M Wang, J Krueger, A Gilkey, E Stelljes, M Kluesner, ... Journal for ImmunoTherapy of Cancer 12 (Suppl 2), 2024 | | 2024 |
Multiplex base editing of primary human natural killer cells W Minjing, BS Moriarity, BR Webber, MG Kluesner, EJ Pomeroy, W Bryce US Patent App. 18/293,288, 2024 | | 2024 |
Efficient multiplex non-viral engineering and expansion of polyclonal γδ CAR-T cells for immunotherapy J Bridge, MJ Johnson, J Kim, S Wenthe, J Krueger, B Wick, M Kluesner, ... bioRxiv, 2024 | | 2024 |
Sensitive bispecific chimeric T cell receptors for cancer therapy S Simon, G Bugos, R Prins, A Rajan, A Palani, K Heyer, A Stevens, ... Research Square, 2024 | | 2024 |
Enhancing efficiency of targeted gene knockin by base editors BR Webber, BS Moriarity, W Lahr, N Slipek, MG Kluesner US Patent App. 18/273,454, 2024 | | 2024 |