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Mitchell Kluesner
Mitchell Kluesner
University of Washington, Fred Hutchinson Cancer Center
在 uw.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
EditR: a method to quantify base editing from Sanger sequencing
MG Kluesner, DA Nedveck, WS Lahr, JR Garbe, JE Abrahante, ...
The CRISPR journal 1 (3), 239-250, 2018
425*2018
Highly efficient multiplex human T cell engineering without double-strand breaks using Cas9 base editors
BR Webber, C Lonetree, MG Kluesner, MJ Johnson, EJ Pomeroy, ...
Nature communications 10 (1), 5222, 2019
2102019
A genetically engineered primary human natural killer cell platform for cancer immunotherapy
EJ Pomeroy, JT Hunzeker, MG Kluesner, WS Lahr, BA Smeester, ...
Molecular Therapy 28 (1), 52-63, 2020
1582020
CRISPR-Cas9 cytidine and adenosine base editing of splice-sites mediates highly-efficient disruption of proteins in primary and immortalized cells
MG Kluesner, WS Lahr, C Lonetree, BA Smeester, X Qiu, NJ Slipek, ...
Nature communications 12 (1), 2437, 2021
882021
Highly multiplexed genome engineering using CRISPR/Cas9 gRNA arrays
M Kurata, NK Wolf, WS Lahr, MT Weg, MG Kluesner, S Lee, K Hui, ...
PLoS one 13 (9), e0198714, 2018
732018
MultiEditR: The first tool for the detection and quantification of RNA editing from Sanger sequencing demonstrates comparable fidelity to RNA-seq
MG Kluesner, RN Tasakis, T Lerner, A Arnold, S Wüst, M Binder, ...
Molecular Therapy-Nucleic Acids 25, 515-523, 2021
24*2021
Correction of Fanconi anemia mutations using digital genome engineering
CJ Sipe, MG Kluesner, SP Bingea, WS Lahr, AA Andrew, M Wang, ...
International journal of molecular sciences 23 (15), 8416, 2022
112022
Highly efficient multiplex human T cell engineering without double-strand breaks using Cas9 base editors. Nat. Commun. 10, 5222
BR Webber, CL Lonetree, MG Kluesner, MJ Johnson, EJ Pomeroy, ...
92019
Signaling via a CD27-TRAF2-SHP-1 axis during naive T cell activation promotes memory-associated gene regulatory networks
CA Jaeger-Ruckstuhl, Y Lo, E Fulton, OG Waltner, TB Shabaneh, S Simon, ...
Immunity 57 (2), 287-302. e12, 2024
82024
Developing bottom-up induced pluripotent stem cell derived solid tumor models using precision genome editing technologies
KL Becklin, GM Draper, RA Madden, MG Kluesner, T Koga, M Huang, ...
The CRISPR journal 5 (4), 517-535, 2022
62022
C-to-U RNA editing: from computational detection to experimental validation
T Lerner, M Kluesner, RN Tasakis, BS Moriarity, FN Papavasiliou, ...
RNA Editing: Methods and Protocols, 51-67, 2021
52021
Precision Enhancement of CAR-NK Cells through Non-Viral Engineering and Highly Multiplexed Base Editing
M Wang, JB Krueger, AK Gilkey, EM Stelljes, MG Kluesner, EJ Pomeroy, ...
bioRxiv, 2024
32024
216 Multiplex base editing of NK cell to enhance cancer immunotherapy
M Wang, M Kluesner, PC Vázquez, B Webber, B Moriarity
Journal for ImmunoTherapy of Cancer 9 (Suppl 2), 2021
22021
Lymphohematopoietic engineering using cas9 base editors
B Moriarity, B Webber, C Lonetree, M Diers, M Kluesner, L Walker, ...
12019
1150 Non-virally engineered polyclonal gamma delta T cells exhibit potent anti-tumor activity in vivo
J Bridge, J Kim, S Wenthe, J Krueger, B Wick, M Kluesner, A Crane, J Bell, ...
Journal for ImmunoTherapy of Cancer 12 (Suppl 2), 2024
2024
347 Highly multiplexed engineering of immune effector cells for advanced cancer therapies
JG Skeate, M Wang, J Krueger, A Gilkey, E Stelljes, M Kluesner, ...
Journal for ImmunoTherapy of Cancer 12 (Suppl 2), 2024
2024
Multiplex base editing of primary human natural killer cells
W Minjing, BS Moriarity, BR Webber, MG Kluesner, EJ Pomeroy, W Bryce
US Patent App. 18/293,288, 2024
2024
Efficient multiplex non-viral engineering and expansion of polyclonal γδ CAR-T cells for immunotherapy
J Bridge, MJ Johnson, J Kim, S Wenthe, J Krueger, B Wick, M Kluesner, ...
bioRxiv, 2024
2024
Sensitive bispecific chimeric T cell receptors for cancer therapy
S Simon, G Bugos, R Prins, A Rajan, A Palani, K Heyer, A Stevens, ...
Research Square, 2024
2024
Enhancing efficiency of targeted gene knockin by base editors
BR Webber, BS Moriarity, W Lahr, N Slipek, MG Kluesner
US Patent App. 18/273,454, 2024
2024
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