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Shane C. Wright
Shane C. Wright
在 ki.se 的电子邮件经过验证
标题
引用次数
引用次数
年份
Agonist-induced dimer dissociation as a macromolecular step in G protein-coupled receptor signaling
J Petersen, SC Wright, D Rodríguez, P Matricon, N Lahav, A Vromen, ...
Nature communications 8 (1), 226, 2017
812017
Frizzleds as GPCRs–more conventional than we thought!
G Schulte, SC Wright
Trends in pharmacological sciences 39 (9), 828-842, 2018
802018
A conserved molecular switch in Class F receptors regulates receptor activation and pathway selection
SC Wright, P Kozielewicz, M Kowalski-Jahn, J Petersen, CF Bowin, ...
Nature communications 10 (1), 667, 2019
682019
FZD5 is a Gαq-coupled receptor that exhibits the functional hallmarks of prototypical GPCRs
SC Wright, MCA Canizal, T Benkel, K Simon, C Le Gouill, P Matricon, ...
Science signaling 11 (559), eaar5536, 2018
602018
Agonist-induced formation of unproductive receptor-G12 complexes
N Okashah, SC Wright, K Kawakami, S Mathiasen, J Zhou, S Lu, ...
Proceedings of the National Academy of Sciences 117 (35), 21723-21730, 2020
442020
Illuminating the complexity of GPCR pathway selectivity–advances in biosensor development
SC Wright, M Bouvier
Current Opinion in Structural Biology 69, 142-149, 2021
372021
BRET-based effector membrane translocation assay monitors GPCR-promoted and endocytosis-mediated Gq activation at early endosomes
SC Wright, V Lukasheva, C Le Gouill, H Kobayashi, B Breton, ...
Proceedings of the National Academy of Sciences 118 (20), e2025846118, 2021
322021
Cryo-EM structure of constitutively active human Frizzled 7 in complex with heterotrimeric Gs
L Xu, B Chen, H Schihada, SC Wright, A Turku, Y Wu, GW Han, ...
Cell research 31 (12), 1311-1314, 2021
292021
Barbadin selectively modulates FPR2-mediated neutrophil functions independent of receptor endocytosis
M Sundqvist, A Holdfeldt, SC Wright, TC Møller, E Siaw, K Jennbacken, ...
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1867 (12), 118849, 2020
202020
GLP-1R signaling neighborhoods associate with the susceptibility to adverse drug reactions of incretin mimetics
SC Wright, A Motso, S Koutsilieri, CM Beusch, P Sabatier, A Berghella, ...
Nature communications 14 (1), 6243, 2023
142023
Organotypic human ex vivo models for coronavirus disease 2019 research and drug development
S Youhanna, SC Wright, VM Lauschke
Current Opinion in Pharmacology 59, 11-18, 2021
52021
Crimean–Congo haemorrhagic fever virus uses LDLR to bind and enter host cells
VM Monteil, SC Wright, M Dyczynski, MJ Kellner, S Appelberg, SW Platzer, ...
Nature Microbiology 9 (6), 1499-1512, 2024
22024
Class Frizzled GPCRs (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database
E Arthofer, J Dijksterhuis, B Hot, P Kozielewicz, M Lauth, J Olofsson, ...
IUPHAR/BPS Guide to Pharmacology CITE 2019 (4), 2019
22019
Rewiring of catecholamine‐induced calcium signalling is an early event in non‐alcoholic fatty liver disease.
SC Wright, VM Lauschke
Journal of Physiology 601 (8), 2023
12023
Altered desensitization and internalization patterns of rodent versus human glucose‐dependent insulinotropic polypeptide (GIP) receptors. An important drug discovery challenge
LS Gasbjerg, RS Rasmussen, A Dragan, P Lindquist, JU Melchiorsen, ...
British Journal of Pharmacology, 2024
2024
Conformation-and activation-based BRET sensors differentially report on GPCR–G protein coupling
SC Wright, C Avet, SA Gaitonde, I Muneta-Arrate, C Le Gouill, M Hogue, ...
Science Signaling 17 (841), eadi4747, 2024
2024
Characterization of genetic variants of GIPR reveals a contribution of β-arrestin to metabolic phenotypes
HS Kizilkaya, KV Sørensen, JS Madsen, P Lindquist, JD Douros, ...
Nature metabolism, 1-14, 2024
2024
The novel adrenergic agonist ATR-127 targets skeletal muscle and brown adipose tissue to tackle diabesity and steatohepatitis
E Talamonti, J Davegardh, A Kalinovich, SMM van Beek, N Dehvari, ...
Molecular Metabolism, 101931, 2024
2024
Discovery of a novel inhibitor of macropinocytosis with antiviral activity
B Porebski, W Christ, A Corman, M Haraldsson, M Barz, L Lidemalm, ...
Molecular Therapy, 2023
2023
Class Frizzled GPCRs in GtoPdb v. 2023.1
E Arthofer, J Dijksterhuis, L Grätz, B Hot, P Kozielewicz, M Lauth, ...
IUPHAR/BPS Guide to Pharmacology CITE 2023 (1), 2023
2023
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