Irreversible inhibitors of serine, cysteine, and threonine proteases JC Powers, JL Asgian, ÖD Ekici, KE James Chemical reviews 102 (12), 4639-4750, 2002 | 1375 | 2002 |
Unconventional serine proteases: variations on the catalytic Ser/His/Asp triad configuration ÖD Ekici, M Paetzel, RE Dalbey Protein Science 17 (12), 2023-2037, 2008 | 378 | 2008 |
Aza-peptide Michael acceptors: a new class of inhibitors specific for caspases and other clan CD cysteine proteases ÖD Ekici, MG Götz, KE James, ZZ Li, BJ Rukamp, JL Asgian, CR Caffrey, ... Journal of medicinal chemistry 47 (8), 1889-1892, 2004 | 108 | 2004 |
Design, synthesis, and evaluation of aza-peptide Michael acceptors as selective and potent inhibitors of caspases-2,-3,-6,-7,-8,-9, and-10 ÖD Ekici, ZZ Li, AJ Campbell, KE James, JL Asgian, J Mikolajczyk, ... Journal of medicinal chemistry 49 (19), 5728-5749, 2006 | 102 | 2006 |
Design, synthesis, and evaluation of aza-peptide epoxides as selective and potent inhibitors of caspases-1,-3,-6, and-8 KE James, JL Asgian, ZZ Li, ÖD Ekici, JR Rubin, J Mikolajczyk, ... Journal of medicinal chemistry 47 (6), 1553-1574, 2004 | 78 | 2004 |
Efforts toward treatments against aging of organophosphorus‐inhibited acetylcholinesterase Q Zhuang, A Young, CS Callam, CA McElroy, ÖD Ekici, RJ Yoder, ... Annals of the New York Academy of Sciences 1374 (1), 94-104, 2016 | 48 | 2016 |
Demonstration of in vitro resurrection of aged acetylcholinesterase after exposure to organophosphorus chemical nerve agents Q Zhuang, AJ Franjesevic, TS Corrigan, WH Coldren, R Dicken, S Sillart, ... Journal of Medicinal Chemistry 61 (16), 7034-7042, 2018 | 41 | 2018 |
Altered-3 substrate specificity of Escherichia coli signal peptidase 1 mutants as revealed by screening a combinatorial peptide library OD Ekici, A Karla, M Paetzel, MO Lively, D Pei, RE Dalbey Journal of Biological Chemistry 282 (1), 417-425, 2007 | 24 | 2007 |
Study of para-Quinone Methide Precursors toward the Realkylation of Aged Acetylcholinesterase RJ Yoder, Q Zhuang, JM Beck, A Franjesevic, TG Blanton, S Sillart, ... ACS medicinal chemistry letters 8 (6), 622-627, 2017 | 17 | 2017 |
Profiling the substrate specificity of viral protease VP4 by a FRET-based peptide library approach OD Ekici, J Zhu, IY Wah Chung, M Paetzel, RE Dalbey, D Pei Biochemistry 48 (24), 5753-5759, 2009 | 15 | 2009 |
Design, synthesis, and in vitro evaluation of aza-peptide aldehydes and ketones as novel and selective protease inhibitors TS Corrigan, LM Lotti Diaz, SE Border, SC Ratigan, KQ Kasper, D Sojka, ... Journal of enzyme inhibition and medicinal chemistry 35 (1), 1387-1402, 2020 | 9 | 2020 |
Signal peptidase enzymology and substrate specificity profiling RE Dalbey, D Pei, ÖD Ekici Methods in enzymology 584, 35-57, 2017 | 9 | 2017 |
Aza-peptide aldehydes and ketones OD Ekici, C Hadad, T Corrigan US Patent App. 16/080,781, 2019 | 8 | 2019 |
Propenoyl hydrazides JC Powers, J Asgian, OD Ekici, MG Gotz, KE James, ZZ Li, B Rukamp | 1 | 2005 |
Design, synthesis, and evaluation of novel azapeptide carbonyls as inhibitors of the 20S proteasome OD Ekici, T Corrigan, K Kasper, LL Diaz, D Ciarlariello, D Benson, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 257, 2019 | | 2019 |
Aza-peptide aldehydes and ketones OD Ekici, C HADAD, T Corrigan | | 2017 |
Aza-peptide aldehydes and ketones: A new class of proteasome inhibitors T Corrigan, K Kasper, R McCauslin, R Yoder, C Hadad, OD Ekici ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 253, 2017 | | 2017 |
Reactivation of aged acetylcholinesterase: design and development of novel therapeutics against exposure to organophosphorus chemical nerve agents Q Zhuang, A Awad, R McKenney, T Blanton, R Dicken, A Franjesevic, ... F1000Research 6, 2015 | | 2015 |
Aza-peptide Michael acceptors: A novel class of potent and selective inhibitors targeting caspases OD Ekici, ZZ Li, AJ Campbell, KE James, JL Asgian, J Mikolajczyk, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 231, 2006 | | 2006 |
Aza-peptide epoxides as inhibitors of caspases: How epoxide stereochemistry and prime side interactions influence reactivity and selectivity AJ Campbell, JL Asgian, J Mikolajczyk, KE James, ZZ Li, OD Ekici, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 230, U2686-U2686, 2005 | | 2005 |