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Ozlem Dogan Ekici
Ozlem Dogan Ekici
Associate Professor of Chemistry and Biochemistry
在 osu.edu 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
Irreversible inhibitors of serine, cysteine, and threonine proteases
JC Powers, JL Asgian, ÖD Ekici, KE James
Chemical reviews 102 (12), 4639-4750, 2002
13752002
Unconventional serine proteases: variations on the catalytic Ser/His/Asp triad configuration
ÖD Ekici, M Paetzel, RE Dalbey
Protein Science 17 (12), 2023-2037, 2008
3782008
Aza-peptide Michael acceptors: a new class of inhibitors specific for caspases and other clan CD cysteine proteases
ÖD Ekici, MG Götz, KE James, ZZ Li, BJ Rukamp, JL Asgian, CR Caffrey, ...
Journal of medicinal chemistry 47 (8), 1889-1892, 2004
1082004
Design, synthesis, and evaluation of aza-peptide Michael acceptors as selective and potent inhibitors of caspases-2,-3,-6,-7,-8,-9, and-10
ÖD Ekici, ZZ Li, AJ Campbell, KE James, JL Asgian, J Mikolajczyk, ...
Journal of medicinal chemistry 49 (19), 5728-5749, 2006
1022006
Design, synthesis, and evaluation of aza-peptide epoxides as selective and potent inhibitors of caspases-1,-3,-6, and-8
KE James, JL Asgian, ZZ Li, ÖD Ekici, JR Rubin, J Mikolajczyk, ...
Journal of medicinal chemistry 47 (6), 1553-1574, 2004
782004
Efforts toward treatments against aging of organophosphorus‐inhibited acetylcholinesterase
Q Zhuang, A Young, CS Callam, CA McElroy, ÖD Ekici, RJ Yoder, ...
Annals of the New York Academy of Sciences 1374 (1), 94-104, 2016
482016
Demonstration of in vitro resurrection of aged acetylcholinesterase after exposure to organophosphorus chemical nerve agents
Q Zhuang, AJ Franjesevic, TS Corrigan, WH Coldren, R Dicken, S Sillart, ...
Journal of Medicinal Chemistry 61 (16), 7034-7042, 2018
412018
Altered-3 substrate specificity of Escherichia coli signal peptidase 1 mutants as revealed by screening a combinatorial peptide library
OD Ekici, A Karla, M Paetzel, MO Lively, D Pei, RE Dalbey
Journal of Biological Chemistry 282 (1), 417-425, 2007
242007
Study of para-Quinone Methide Precursors toward the Realkylation of Aged Acetylcholinesterase
RJ Yoder, Q Zhuang, JM Beck, A Franjesevic, TG Blanton, S Sillart, ...
ACS medicinal chemistry letters 8 (6), 622-627, 2017
172017
Profiling the substrate specificity of viral protease VP4 by a FRET-based peptide library approach
OD Ekici, J Zhu, IY Wah Chung, M Paetzel, RE Dalbey, D Pei
Biochemistry 48 (24), 5753-5759, 2009
152009
Design, synthesis, and in vitro evaluation of aza-peptide aldehydes and ketones as novel and selective protease inhibitors
TS Corrigan, LM Lotti Diaz, SE Border, SC Ratigan, KQ Kasper, D Sojka, ...
Journal of enzyme inhibition and medicinal chemistry 35 (1), 1387-1402, 2020
92020
Signal peptidase enzymology and substrate specificity profiling
RE Dalbey, D Pei, ÖD Ekici
Methods in enzymology 584, 35-57, 2017
92017
Aza-peptide aldehydes and ketones
OD Ekici, C Hadad, T Corrigan
US Patent App. 16/080,781, 2019
82019
Propenoyl hydrazides
JC Powers, J Asgian, OD Ekici, MG Gotz, KE James, ZZ Li, B Rukamp
12005
Design, synthesis, and evaluation of novel azapeptide carbonyls as inhibitors of the 20S proteasome
OD Ekici, T Corrigan, K Kasper, LL Diaz, D Ciarlariello, D Benson, ...
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 257, 2019
2019
Aza-peptide aldehydes and ketones
OD Ekici, C HADAD, T Corrigan
2017
Aza-peptide aldehydes and ketones: A new class of proteasome inhibitors
T Corrigan, K Kasper, R McCauslin, R Yoder, C Hadad, OD Ekici
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 253, 2017
2017
Reactivation of aged acetylcholinesterase: design and development of novel therapeutics against exposure to organophosphorus chemical nerve agents
Q Zhuang, A Awad, R McKenney, T Blanton, R Dicken, A Franjesevic, ...
F1000Research 6, 2015
2015
Aza-peptide Michael acceptors: A novel class of potent and selective inhibitors targeting caspases
OD Ekici, ZZ Li, AJ Campbell, KE James, JL Asgian, J Mikolajczyk, ...
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 231, 2006
2006
Aza-peptide epoxides as inhibitors of caspases: How epoxide stereochemistry and prime side interactions influence reactivity and selectivity
AJ Campbell, JL Asgian, J Mikolajczyk, KE James, ZZ Li, OD Ekici, ...
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 230, U2686-U2686, 2005
2005
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