Novel Single Chain cAMP Sensors for Receptor-induced Signal Propagation*♦ VO Nikolaev, M Bunemann, L Hein, A Hannawacker, MJ Lohse Journal of Biological Chemistry 279 (36), 37215-37218, 2004 | 848 | 2004 |
High Levels of Circulating Epinephrine Trigger Apical Cardiodepression in a β2-Adrenergic Receptor/Gi–Dependent Manner: A New Model of Takotsubo … H Paur, PT Wright, MB Sikkel, MH Tranter, C Mansfield, P O'gara, ... Circulation 126 (6), 697-706, 2012 | 819 | 2012 |
β2-adrenergic receptor redistribution in heart failure changes cAMP compartmentation VO Nikolaev, A Moshkov, AR Lyon, M Miragoli, P Novak, H Paur, ... Science 327 (5973), 1653-1657, 2010 | 666 | 2010 |
Persistent cAMP-signals triggered by internalized G-protein–coupled receptors D Calebiro, VO Nikolaev, MC Gagliani, T De Filippis, C Dees, C Tacchetti, ... PLoS biology 7 (8), e1000172, 2009 | 631 | 2009 |
Cyclic GMP from the surrounding somatic cells regulates cyclic AMP and meiosis in the mouse oocyte RP Norris, WJ Ratzan, M Freudzon, LM Mehlmann, J Krall, MA Movsesian, ... Oxford University Press for The Company of Biologists Limited 136 (11), 1869 …, 2009 | 589 | 2009 |
Cyclic AMP Imaging in Adult Cardiac Myocytes Reveals Far-Reaching β1-Adrenergic but Locally Confined β2-Adrenergic Receptor–Mediated Signaling VO Nikolaev, M Bünemann, E Schmitteckert, MJ Lohse, S Engelhardt Circulation research 99 (10), 1084-1091, 2006 | 396 | 2006 |
Sweet taste receptor expressed in pancreatic β-cells activates the calcium and cyclic AMP signaling systems and stimulates insulin secretion Y Nakagawa, M Nagasawa, S Yamada, A Hara, H Mogami, VO Nikolaev, ... PloS one 4 (4), e5106, 2009 | 368 | 2009 |
Externalized histone H4 orchestrates chronic inflammation by inducing lytic cell death C Silvestre-Roig, Q Braster, K Wichapong, EY Lee, JM Teulon, ... Nature 569 (7755), 236-240, 2019 | 346 | 2019 |
Widespread receptivity to neuropeptide PDF throughout the neuronal circadian clock network of Drosophila revealed by real-time cyclic AMP imaging OT Shafer, DJ Kim, R Dunbar-Yaffe, VO Nikolaev, MJ Lohse, PH Taghert Neuron 58 (2), 223-237, 2008 | 346 | 2008 |
Conformational cross-talk between α2A-adrenergic and μ-opioid receptors controls cell signaling JP Vilardaga, VO Nikolaev, K Lorenz, S Ferrandon, Z Zhuang, MJ Lohse Nature chemical biology 4 (2), 126-131, 2008 | 309 | 2008 |
Signaling by internalized G-protein-coupled receptors D Calebiro, VO Nikolaev, L Persani, MJ Lohse Trends in pharmacological sciences 31 (5), 221-228, 2010 | 308 | 2010 |
FRET measurements of intracellular cAMP concentrations and cAMP analog permeability in intact cells S Börner, F Schwede, A Schlipp, F Berisha, D Calebiro, MJ Lohse, ... Nature protocols 6 (4), 427-438, 2011 | 256 | 2011 |
Interplay of Ca2+ and cAMP Signaling in the Insulin-secreting MIN6 β-Cell Line*[boxs] LR Landa, M Harbeck, K Kaihara, O Chepurny, K Kitiphongspattana, ... Journal of Biological Chemistry 280 (35), 31294-31302, 2005 | 225 | 2005 |
Fluorescent sensors for rapid monitoring of intracellular cGMP VO Nikolaev, S Gambaryan, MJ Lohse Nature methods 3 (1), 23-25, 2006 | 222 | 2006 |
Turn-on switch in parathyroid hormone receptor by a two-step parathyroid hormone binding mechanism M Castro, VO Nikolaev, D Palm, MJ Lohse, JP Vilardaga Proceedings of the National Academy of Sciences 102 (44), 16084-16089, 2005 | 204 | 2005 |
Atrial myocyte NLRP3/CaMKII nexus forms a substrate for postoperative atrial fibrillation J Heijman, AP Muna, T Veleva, CE Molina, H Sutanto, M Tekook, Q Wang, ... Circulation research 127 (8), 1036-1055, 2020 | 188 | 2020 |
Real-time optical recording of β1-adrenergic receptor activation reveals supersensitivity of the Arg389 variant to carvedilol F Rochais, JP Vilardaga, VO Nikolaev, M Bünemann, MJ Lohse, ... The Journal of clinical investigation 117 (1), 229-235, 2007 | 180 | 2007 |
GLP-1 stimulates insulin secretion by PKC-dependent TRPM4 and TRPM5 activation M Shigeto, R Ramracheya, AI Tarasov, CY Cha, MV Chibalina, B Hastoy, ... The Journal of clinical investigation 125 (12), 4714-4728, 2015 | 177 | 2015 |
Spatiotemporal Dynamics of β-Adrenergic cAMP Signals and L-Type Ca2+ Channel Regulation in Adult Rat Ventricular Myocytes: Role of Phosphodiesterases J Leroy, A Abi-Gerges, VO Nikolaev, W Richter, P Lechêne, JL Mazet, ... Circulation research 102 (9), 1091-1100, 2008 | 175 | 2008 |
Gs activation is time-limiting in initiating receptor-mediated signaling P Hein, F Rochais, C Hoffmann, S Dorsch, VO Nikolaev, S Engelhardt, ... Journal of Biological Chemistry 281 (44), 33345-33351, 2006 | 171 | 2006 |