关注
Ha T. Do
Ha T. Do
Principal Scientist, Reata Pharmaceuticals Inc.
在 reatapharma.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Inducible nitric oxide synthase: Regulation, structure, and inhibition
MA Cinelli, HT Do, GP Miley, RB Silverman
Medicinal research reviews 40 (1), 158-189, 2020
5802020
Optimization of blood–brain barrier permeability with potent and selective human neuronal nitric oxide synthase inhibitors having a 2-aminopyridine scaffold
HT Do, H Li, G Chreifi, TL Poulos, RB Silverman
Journal of medicinal chemistry 62 (5), 2690-2707, 2019
342019
Pharmacophore-based design of novel 3-hydroxypyrimidine-2, 4-dione subtypes as inhibitors of HIV reverse transcriptase-associated RNase H: tolerance of a nonflexible linker
J Tang, HT Do, AD Huber, MC Casey, KA Kirby, DJ Wilson, J Kankanala, ...
European journal of medicinal chemistry 166, 390-399, 2019
262019
Chemical profiling of HIV-1 capsid-targeting antiviral PF74
L Wang, MC Casey, SKV Vernekar, HT Do, RL Sahani, KA Kirby, H Du, ...
European journal of medicinal chemistry 200, 112427, 2020
222020
Enantioselective Synthesis of (−)-Dysiherbaine
H Do, CW Kang, JH Cho, SR Gilbertson
Organic letters 17 (16), 3972-3974, 2015
192015
Improvement of cell permeability of human neuronal nitric oxide synthase inhibitors using potent and selective 2-aminopyridine-based scaffolds with a fluorobenzene linker
HT Do, HY Wang, H Li, G Chreifi, TL Poulos, RB Silverman
Journal of medicinal chemistry 60 (22), 9360-9375, 2017
162017
Synthesis and activity of benzimidazole-1, 3-dioxide inhibitors of separase
HT Do, N Zhang, D Pati, SR Gilbertson
Bioorganic & Medicinal Chemistry Letters 26 (18), 4446-4450, 2016
112016
Potent, Selective, and Membrane Permeable 2-Amino-4-Substituted Pyridine-Based Neuronal Nitric Oxide Synthase Inhibitors
D Vasu, HT Do, H Li, CD Hardy, A Awasthi, TL Poulos, RB Silverman
Journal of Medicinal Chemistry 66 (14), 9934-9953, 2023
32023
Pregabalin Treatment does not Affect Amyloid Pathology in 5XFAD Mice
KR Sadleir, J Popovoic, W Zhu, CT Reidel, H Do, RB Silverman, R Vassar
Current Alzheimer Research 18 (4), 283, 2021
32021
Synthetic triterpenoids with nitrogen-​based substituents at C-​17 and methods of use thereof
CF Bender, H Do, X Jiang, H Sun, M Visnick, I Janser, LJ Simons, ...
WO Patent 2,021,127,480, 2021
12021
Correction to improvement of cell permeability of human neuronal nitric oxide synthase inhibitors using potent and selective 2-aminopyridine-based scaffolds with a …
HT Do, HY Wang, H Li, G Chreifi, TL Poulos, RB Silverman
Journal of medicinal chemistry 62 (2), 1074-1074, 2018
12018
Synthesis of ursolic acid antioxidant inflammation modulators treating inflammation disorders and cancers
X Jiang, H Do, H Sun, M Visnick, J Kral, Robert M.
WO Patent 2,022,155,614, 2022
2022
Preparation of 2-​aminopyridines as potent human neuronal nitric oxide synthase inhibitors for the treatment of neurological diseases
RB Silverman, HT Do
WO Patent 2,021,173,111, 2021
2021
Synthesis of dimeric compounds as STING agonists
JR Duvall, KW Bentley, HT Do, BD Jones, NI Kauser, EW Kelleher, ...
WO Patent 2,021,113,679, 2021
2021
C17 polar-substituted heteroaromatic synthetic triterpenoids and methods of use thereof
X Jiang, CF Bender, H Do, SUN Haizhou, M Visnick
US Patent App. 16/933,635, 2021
2021
Preparation of C17 polar-​substituted heteroaromatic synthetic triterpenoids as antioxidant inflammation modulators
X Jiang, CF Bender, H Do, H Sun, M Visnick
US Patent 20,210,040,142, 2021
2021
Synthesis of Dysiherbaine and Separase Inhibitors in Drug Development for Neural Disorders and Breast Cancer
HT Do
2015
Synthesis of dysiherbaine and its analogs
HT Do, SR Gilbertson
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 245, 2013
2013
Supplementary Material Pregabalin Treatment does not Affect Amyloid Pathology in 5XFAD Mice
KR Sadleir, J Popovoic, W Zhu, CT Reidel, H Do, RB Silverman, R Vassar
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