| The four-herb Chinese medicine PHY906 reduces chemotherapy-induced gastrointestinal toxicity W Lam, S Bussom, F Guan, Z Jiang, W Zhang, EA Gullen, SH Liu, ... Science translational medicine 2 (45), 45ra59-45ra59, 2010 | 408 | 2010 |
| Safety surveillance of traditional Chinese medicine: current and future SH Liu, WC Chuang, W Lam, Z Jiang, YC Cheng Drug safety 38, 117-128, 2015 | 271 | 2015 |
| Novel mode of action of tylophorine analogs as antitumor compounds W Gao, W Lam, S Zhong, C Kaczmarek, DC Baker, YC Cheng Cancer research 64 (2), 678-688, 2004 | 209 | 2004 |
| Nucleoplasmic calcium is required for cell proliferation MA Rodrigues, DA Gomes, MF Leite, W Grant, L Zhang, W Lam, ... Journal of Biological Chemistry 282 (23), 17061-17068, 2007 | 172 | 2007 |
| Novel mechanism of inhibition of nuclear factor-κB DNA-binding activity by diterpenoids isolated from Isodon rubescens CH Leung, SP Grill, W Lam, QB Han, HD Sun, YC Cheng Molecular pharmacology 68 (2), 286-297, 2005 | 170 | 2005 |
| Major achievements of evidence-based traditional Chinese medicine in treating major diseases J Chao, Y Dai, R Verpoorte, W Lam, YC Cheng, LH Pao, W Zhang, ... Biochemical pharmacology 139, 94-104, 2017 | 141 | 2017 |
| Phosphorylation of pyrimidine deoxynucleoside analog diphosphates: selective phosphorylation of L-nucleoside analog diphosphates by 3-phosphoglycerate kinase P Krishnan, Q Fu, W Lam, JY Liou, G Dutschman, YC Cheng Journal of Biological Chemistry 277 (7), 5453-5459, 2002 | 120 | 2002 |
| PHY906 (KD018), an adjuvant based on a 1800-year-old Chinese medicine, enhanced the anti-tumor activity of Sorafenib by changing the tumor microenvironment W Lam, Z Jiang, F Guan, X Huang, R Hu, J Wang, S Bussom, SH Liu, ... Scientific reports 5 (1), 9384, 2015 | 117 | 2015 |
| Characterization of Human UMP/CMP Kinase and Its Phosphorylation of d- and l-Form Deoxycytidine Analogue Monophosphates JY Liou, GE Dutschman, W Lam, Z Jiang, YC Cheng Cancer research 62 (6), 1624-1631, 2002 | 115 | 2002 |
| Simple and convenient G-quadruplex-based turn-on fluorescence assay for 3′→ 5′ exonuclease activity CH Leung, DSH Chan, BYW Man, CJ Wang, W Lam, YC Cheng, WF Fong, ... Analytical chemistry 83 (2), 463-466, 2011 | 109 | 2011 |
| Antibacterial flavonoids from medicinal plants covalently inactivate type III protein secretion substrates LK Tsou, M Lara-Tejero, J RoseFigura, ZJ Zhang, YC Wang, JS Yount, ... Journal of the American Chemical Society 138 (7), 2209-2218, 2016 | 108 | 2016 |
| Identification of chemicals and their metabolites from PHY906, a Chinese medicine formulation, in the plasma of a patient treated with irinotecan and PHY906 using liquid … W Zhang, MW Saif, GE Dutschman, X Li, W Lam, S Bussom, Z Jiang, M Ye, ... Journal of Chromatography A 1217 (37), 5785-5793, 2010 | 98 | 2010 |
| Targeting tumour microenvironment by tyrosine kinase inhibitor HY Tan, N Wang, W Lam, W Guo, Y Feng, YC Cheng Molecular cancer 17 (1), 1-15, 2018 | 94 | 2018 |
| Impairment of APE1 function enhances cellular sensitivity to clinically relevant alkylators and antimetabolites DR McNeill, W Lam, TL DeWeese, YC Cheng, DM Wilson III Molecular Cancer Research 7 (6), 897-906, 2009 | 93 | 2009 |
| X-ray repair cross-complementing gene I protein plays an important role in camptothecin resistance SY Park, W Lam, Y Cheng Cancer research 62 (2), 459-465, 2002 | 90 | 2002 |
| Interaction of a traditional Chinese Medicine (PHY906) and CPT-11 on the inflammatory process in the tumor microenvironment E Wang, S Bussom, J Chen, C Quinn, D Bedognetti, W Lam, F Guan, ... BMC medical genomics 4 (1), 1-13, 2011 | 89 | 2011 |
| Eriocalyxin B inhibits nuclear factor-κB activation by interfering with the binding of both p65 and p50 to the response element in a noncompetitive manner CH Leung, SP Grill, W Lam, W Gao, HD Sun, YC Cheng Molecular pharmacology 70 (6), 1946-1955, 2006 | 88 | 2006 |
| Butyrate mediates nucleotide‐binding and oligomerisation domain (NOD) 2‐dependent mucosal immune responses against peptidoglycan CH Leung, W Lam, DL Ma, EA Gullen, YC Cheng European journal of immunology 39 (12), 3529-3537, 2009 | 65 | 2009 |
| Antiretroviral therapy–induced mitochondrial toxicity: potential mechanisms beyond polymerase‐γ inhibition S Selvaraj, M Ghebremichael, M Li, Y Foli, A Langs‐Barlow, A Ogbuagu, ... Clinical Pharmacology & Therapeutics 96 (1), 110-120, 2014 | 49 | 2014 |
| Low-level doxorubicin resistance in benzo [a] pyrene-treated KB-3-1 cells is associated with increased LRP expression and altered subcellular drug distribution SH Cheng, W Lam, ASK Lee, KP Fung, RSS Wu, WF Fong Toxicology and applied pharmacology 164 (2), 134-142, 2000 | 48 | 2000 |
