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Rachel Marty Pyke
Rachel Marty Pyke
Personalis, Inc
在 personalis.com 的电子邮件经过验证
标题
引用次数
引用次数
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MHC-I genotype restricts the oncogenic mutational landscape
R Marty, S Kaabinejadian, D Rossell, MJ Slifker, J van de Haar, HB Engin, ...
Cell 171 (6), 1272-1283. e15, 2017
3322017
Evolutionary pressure against MHC class II binding cancer mutations
RM Pyke, WK Thompson, RM Salem, M Zanetti, H Carter
Cell 175 (2), 416-428. e13, 2018
2062018
Interaction landscape of inherited polymorphisms with somatic events in cancer
H Carter, R Marty, M Hofree, AM Gross, J Jensen, KM Fisch, X Wu, ...
Cancer discovery 7 (4), 410-423, 2017
1502017
Elevated neoantigen levels in tumors with somatic mutations in the HLA-A, HLA-B, HLA-C and B2M genes
A Castro, K Ozturk, RM Pyke, S Xian, M Zanetti, H Carter
BMC medical genomics 12, 1-13, 2019
922019
MHC-I genotype and tumor mutational burden predict response to immunotherapy
AM Goodman, A Castro, RM Pyke, R Okamura, S Kato, P Riviere, ...
Genome medicine 12, 1-13, 2020
862020
Integrative genomic analysis of mouse and human hepatocellular carcinoma
M Dow, RM Pyke, BY Tsui, LB Alexandrov, H Nakagawa, K Taniguchi, ...
Proceedings of the National Academy of Sciences 115 (42), E9879-E9888, 2018
852018
Strength of immune selection in tumors varies with sex and age
A Castro, RM Pyke, X Zhang, WK Thompson, CP Day, LB Alexandrov, ...
Nature communications 11 (1), 4128, 2020
842020
Prediction of immunotherapy response in melanoma through combined modeling of neoantigen burden and immune-related resistance mechanisms
CW Abbott, SM Boyle, RM Pyke, LD McDaniel, E Levy, FCP Navarro, ...
Clinical Cancer Research 27 (15), 4265-4276, 2021
362021
Precision neoantigen discovery using large-scale immunopeptidomes and composite modeling of MHC peptide presentation
RM Pyke, D Mellacheruvu, S Dea, CW Abbott, SV Zhang, NA Phillips, ...
Molecular & Cellular Proteomics 20, 2021
352021
Immune DNA signature of T-cell infiltration in breast tumor exomes
E Levy, R Marty, V Gárate Calderón, B Woo, M Dow, R Armisen, H Carter, ...
Scientific reports 6 (1), 30064, 2016
312016
Interaction landscape of inherited polymorphisms with somatic events in cancer. Cancer Discov. 2017; 7: 410–423. doi: 10.1158/2159-8290
H Carter, R Marty, M Hofree, AM Gross, J Jensen, KM Fisch, X Wu, ...
CD-16-1045.[Europe PMC free article][Abstract][CrossRef][Google Scholar], 0
26
High-‐resolution shot capture reveals systematic biases and an improved method for shooter evaluation
R Marty
112018
A data-driven method for understanding and increasing 3-point shooting percentage
R Marty, S Lucey
MIT Sloan Sports Analytics Conference, 2017
102017
A machine learning algorithm with subclonal sensitivity reveals widespread pan-cancer human leukocyte antigen loss of heterozygosity
RM Pyke, D Mellacheruvu, S Dea, CW Abbott, L McDaniel, DP Bhave, ...
Nature Communications 13 (1), 1925, 2022
92022
MHC-I genotype drives early immune selection of oncogenic mutations
R Marty, N De Prisco, H Carter, J Font-Burgada
Molecular & cellular oncology 5 (2), e1409863, 2018
52018
A high sensitivity, tumor-informed liquid biopsy platform, designed to detect minimal residual disease at part per million resolution
SM Boyle, G Bartha, J Lyle, J Harris, J Northcott, D Norton, RM Pyke, ...
Cancer Research 82 (12_Supplement), 5163-5163, 2022
32022
Association of HLA loss of heterozygosity with allele-specific neoantigen expansion in response to immunotherapy.
RM Pyke, C Abbott, S Dea, N Bedi, AD Colevas, E Levy, SV Zhang, ...
Journal of Clinical Oncology 39 (15_suppl), e18030-e18030, 2021
32021
P04. 02 A high sensitivity, tumor-informed liquid biopsy platform, designed to detect minimum residual disease at part per million resolution
M Pruess, E Newburn, SM Boyle, D Norton, RM Pyke, F Navarro, J West, ...
Journal for ImmunoTherapy of Cancer 10 (Suppl 1), 2022
22022
Computational KIR copy number discovery reveals interaction between inhibitory receptor burden and survival
RM Pyke, R Genolet, A Harari, G Coukos, D Gfeller, H Carter
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing 24, 148, 2019
22019
Analytical validation of NeXT Personal®, an ultra-sensitive personalized circulating tumor DNA assay
J Northcott, G Bartha, J Harris, C Li, FCP Navarro, RM Pyke, M Hong, ...
Oncotarget 15, 200, 2024
12024
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