SurvExpress: an online biomarker validation tool and database for cancer gene expression data using survival analysis R Aguirre-Gamboa, H Gomez-Rueda, E Martínez-Ledesma, ... PloS one 8 (9), e74250, 2013 | 703 | 2013 |
A functional genomics approach to understand variation in cytokine production in humans Y Li, M Oosting, SP Smeekens, M Jaeger, R Aguirre-Gamboa, KTT Le, ... Cell 167 (4), 1099-1110. e14, 2016 | 327 | 2016 |
DNA methylation in childhood asthma: an epigenome-wide meta-analysis CJ Xu, C Söderhäll, M Bustamante, N Baïz, O Gruzieva, U Gehring, ... The lancet Respiratory medicine 6 (5), 379-388, 2018 | 212 | 2018 |
Differential effects of environmental and genetic factors on T and B cell immune traits R Aguirre-Gamboa, I Joosten, PCM Urbano, RG van der Molen, ... Cell reports 17 (9), 2474-2487, 2016 | 182 | 2016 |
Effect of host genetics on the gut microbiome in 7,738 participants of the Dutch Microbiome Project EA Lopera-Maya, A Kurilshikov, A van der Graaf, S Hu, ... Nature genetics 54 (2), 143-151, 2022 | 178 | 2022 |
Integration of multi-omics data and deep phenotyping enables prediction of cytokine responses OB Bakker, R Aguirre-Gamboa, S Sanna, M Oosting, SP Smeekens, ... Nature immunology 19 (7), 776-786, 2018 | 120 | 2018 |
Sex-specific regulation of inflammation and metabolic syndrome in obesity R Ter Horst, ICL van den Munckhof, K Schraa, R Aguirre-Gamboa, ... Arteriosclerosis, thrombosis, and vascular biology 40 (7), 1787-1800, 2020 | 102 | 2020 |
Cerebral tryptophan metabolism and outcome of tuberculous meningitis: an observational cohort study A van Laarhoven, S Dian, R Aguirre-Gamboa, J Avila-Pacheco, ... The Lancet Infectious Diseases 18 (5), 526-535, 2018 | 84 | 2018 |
Understanding human immune function using the resources from the Human Functional Genomics Project MG Netea, LAB Joosten, Y Li, V Kumar, M Oosting, S Smeekens, ... Nature medicine 22 (8), 831-833, 2016 | 73 | 2016 |
ER stress and UPR activation in glioblastoma: identification of a noncanonical PERK mechanism regulating GBM stem cells through SOX2 modulation NM Peñaranda-Fajardo, C Meijer, Y Liang, BM Dijkstra, ... Cell death & disease 10 (10), 690, 2019 | 72 | 2019 |
Deconvolution of bulk blood eQTL effects into immune cell subpopulations R Aguirre-Gamboa, N de Klein, J di Tommaso, A Claringbould, ... BMC bioinformatics 21, 1-23, 2020 | 52 | 2020 |
The inter-relationship of platelets with interleukin-1β-mediated inflammation in humans RN Tunjungputri, Y Li, PG de Groot, CA Dinarello, SP Smeekens, ... Thrombosis and haemostasis 118 (12), 2112-2125, 2018 | 50 | 2018 |
SurvMicro: assessment of miRNA-based prognostic signatures for cancer clinical outcomes by multivariate survival analysis R Aguirre-Gamboa, V Trevino Bioinformatics 30 (11), 1630-1632, 2014 | 47 | 2014 |
TNF-α–induced protein 3 (TNFAIP3)/A20 acts as a master switch in TNF-α blockade–driven IL-17A expression PCM Urbano, R Aguirre-Gamboa, A Ashikov, B van Heeswijk, ... Journal of Allergy and Clinical Immunology 142 (2), 517-529, 2018 | 40 | 2018 |
Running‐wheel activity delays mitochondrial respiratory flux decline in aging mouse muscle via a post‐transcriptional mechanism S Stolle, J Ciapaite, AC Reijne, A Talarovicova, JC Wolters, ... Aging cell 17 (1), e12700, 2018 | 38 | 2018 |
Integration of metabolomics, genomics, and immune phenotypes reveals the causal roles of metabolites in disease X Chu, M Jaeger, J Beumer, OB Bakker, R Aguirre-Gamboa, M Oosting, ... Genome biology 22, 1-22, 2021 | 35 | 2021 |
Systematic Prioritization of Candidate Genes in Disease Loci Identifies TRAFD1 as a Master Regulator of IFNγ Signaling in Celiac Disease A Van der Graaf, MM Zorro, A Claringbould, U Vosa, R Aguirre-Gamboa, ... Frontiers in Genetics 11, 562434, 2021 | 33 | 2021 |
An integrative genomics approach identifies KDM4 as a modulator of trained immunity SJ Moorlag, V Matzaraki, JH van Puffelen, C van der Heijden, S Keating, ... European journal of immunology 52 (3), 431-446, 2022 | 30 | 2022 |
A genome-wide functional genomics approach identifies susceptibility pathways to fungal bloodstream infection in humans M Jaeger, V Matzaraki, R Aguirre-Gamboa, MS Gresnigt, X Chu, ... The Journal of Infectious Diseases 220 (5), 862-872, 2019 | 22 | 2019 |
Seasonal and nonseasonal longitudinal variation of immune function R Ter Horst, M Jaeger, L van de Wijer, WA van der Heijden, ... The Journal of Immunology 207 (2), 696-708, 2021 | 21 | 2021 |