Functional rafts in cell membranes K Simons, E Ikonen nature 387 (6633), 569-572, 1997 | 12126 | 1997 |
A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD AE Renton, E Majounie, A Waite, J Simón-Sánchez, S Rollinson, ... Neuron 72 (2), 257-268, 2011 | 4774 | 2011 |
Cellular cholesterol trafficking and compartmentalization E Ikonen Nature reviews Molecular cell biology 9 (2), 125-138, 2008 | 1695 | 2008 |
How cells handle cholesterol K Simons, E Ikonen Science 290 (5497), 1721-1726, 2000 | 1614 | 2000 |
Roles of lipid rafts in membrane transport E Ikonen Current opinion in cell biology 13 (4), 470-477, 2001 | 831 | 2001 |
A caveolin dominant negative mutant associates with lipid bodies and induces intracellular cholesterol imbalance A Pol, R Luetterforst, M Lindsay, S Heino, E Ikonen, RG Parton The Journal of cell biology 152 (5), 1057-1070, 2001 | 390 | 2001 |
Caveolin-1 and-2 in the exocytic pathway of MDCK cells P Scheiffele, P Verkade, AM Fra, H Virta, K Simons, E Ikonen The Journal of cell biology 140 (4), 795-806, 1998 | 369 | 1998 |
The impact of low-frequency and rare variants on lipid levels I Surakka, M Horikoshi, R Mägi, AP Sarin, A Mahajan, V Lagou, L Marullo, ... Nature genetics 47 (6), 589-597, 2015 | 367 | 2015 |
Mechanisms for cellular cholesterol transport: defects and human disease E Ikonen Physiological reviews 86 (4), 1237-1261, 2006 | 320 | 2006 |
Dissecting the role of the Golgi complex and lipid rafts in biosynthetic transport of cholesterol to the cell surface S Heino, S Lusa, P Somerharju, C Ehnholm, VM Olkkonen, E Ikonen Proceedings of the National Academy of Sciences 97 (15), 8375-8380, 2000 | 312 | 2000 |
Seipin regulates ER–lipid droplet contacts and cargo delivery VT Salo, I Belevich, S Li, L Karhinen, H Vihinen, C Vigouroux, J Magré, ... The EMBO journal 35 (24), 2699-2716, 2016 | 295 | 2016 |
BODIPY‐cholesterol: a new tool to visualize sterol trafficking in living cells and organisms M Hölttä‐Vuori, RL Uronen, J Repakova, E Salonen, I Vattulainen, ... Traffic 9 (11), 1839-1849, 2008 | 286 | 2008 |
Different requirements for NSF, SNAP, and Rab proteins in apical and basolateral transport in MDCK cells E Ikonen, M Tagaya, O Ullrich, C Montecucco, K Simons Cell 81 (4), 571-580, 1995 | 285 | 1995 |
The OSBP-related protein family in humans M Lehto, S Laitinen, G Chinetti, M Johansson, C Ehnholm, B Staels, ... Journal of lipid research 42 (8), 1203-1213, 2001 | 242 | 2001 |
Protein and lipid sorting from thetrans–Golgi network to the plasma membrane in polarized cells E Ikonen, K Simons Seminars in cell & developmental biology 9 (5), 503-509, 1998 | 228 | 1998 |
Aster proteins facilitate nonvesicular plasma membrane to ER cholesterol transport in mammalian cells J Sandhu, S Li, L Fairall, SG Pfisterer, JE Gurnett, X Xiao, TA Weston, ... Cell 175 (2), 514-529. e20, 2018 | 222 | 2018 |
Prohibitin, an antiproliferative protein, is localized to mitochondria E Ikonen, K Fiedler, RG Parton, K Simons FEBS letters 358 (3), 273-277, 1995 | 220 | 1995 |
Zebrafish: gaining popularity in lipid research M Hölttä-Vuori, VTV Salo, L Nyberg, C Brackmann, A Enejder, P Panula, ... Biochemical Journal 429 (2), 235-242, 2010 | 210 | 2010 |
Dynamic association of human insulin receptor with lipid rafts in cells lacking caveolae S Vainio, S Heino, JE Månsson, P Fredman, E Kuismanen, O Vaarala, ... EMBO reports, 2002 | 200 | 2002 |
Intracellular and secreted Alzheimer β-amyloid species are generated by distinct mechanisms in cultured hippocampal neurons PJ Tienari, N Ida, E Ikonen, M Simons, A Weidemann, G Multhaup, ... Proceedings of the National Academy of Sciences 94 (8), 4125-4130, 1997 | 194 | 1997 |