Loss of KDM6A Activates Super-Enhancers to Induce Gender-Specific Squamous-like Pancreatic Cancer and Confers Sensitivity to BET Inhibitors J Andricovich, S Perkail, Y Kai, N Casasanta, W Peng, A Tzatsos Cancer cell 33 (3), 512-526. e8, 2018 | 267 | 2018 |
miR-137 mediates the functional link between c-Myc and EZH2 that regulates cisplatin resistance in ovarian cancer J Sun, X Cai, MMH Yung, W Zhou, J Li, Y Zhang, Z Li, SS Liu, ... Oncogene 38 (4), 564, 2019 | 123 | 2019 |
Histone demethylase KDM2B regulates lineage commitment in normal and malignant hematopoiesis AT Jaclyn Andricovich, Yan Kai, Weiqun Peng, Adlen Foudi Journal of Clinical Investigation, 2016 | 92 | 2016 |
Transcription factor competition at the γ-globin promoters controls hemoglobin switching N Liu, S Xu, Q Yao, Q Zhu, Y Kai, JY Hsu, P Sakon, L Pinello, GC Yuan, ... Nature Genetics 53 (4), 511-520, 2021 | 74 | 2021 |
DUOXA1-mediated ROS production promotes cisplatin resistance by activating ATR-Chk1 pathway in ovarian cancer Y Meng, CW Chen, MMH Yung, W Sun, J Sun, Z Li, J Li, Z Li, W Zhou, ... Cancer Letters, 2018 | 66 | 2018 |
Predicting CTCF-mediated chromatin interactions by integrating genomic and epigenomic features Y Kai, J Andricovich, Z Zeng, J Zhu, A Tzatsos, W Peng Nature Communications 9 (1), 4221, 2018 | 55 | 2018 |
Highly stable and AC electric field-activated electrorheological fluid based on mesoporous silica-coated graphene nanosheets J Yin, R Chang, Y Kai, X Zhao Soft Matter 9 (15), 3910-3914, 2013 | 44 | 2013 |
Autocrine activation of JAK2 by IL-11 promotes platinum drug resistance W Zhou, W Sun, MMH Yung, S Dai, Y Cai, CW Chen, Y Meng, JB Lee, ... Oncogene, 1, 2018 | 35 | 2018 |
Inner nuclear protein Matrin-3 coordinates cell differentiation by stabilizing chromatin architecture HJ Cha, Ö Uyan*, Y Kai*, T Liu, Q Zhu, Z Tothova, GA Botten, J Xu, ... Nature Communications 12 (1), 1-19, 2021 | 32 | 2021 |
MLL:: AF9 degradation induces rapid changes in transcriptional elongation and subsequent loss of an active chromatin landscape SN Olsen, L Godfrey, JP Healy, YA Choi, Y Kai, C Hatton, F Perner, ... Molecular Cell 82 (6), 1140-1155. e11, 2022 | 29 | 2022 |
Mapping the evolving landscape of super-enhancers during cell differentiation Y Kai, BE Li, M Zhu, GY Li, F Chen, Y Han, HJ Cha, SH Orkin, W Cai, ... Genome Biology 22, 1-21, 2021 | 26 | 2021 |
dbVar structural variant cluster set for data analysis and variant comparison L Phan, J Hsu, M Willi, T Mansour, Y Kai, J Garner, J Lopez, B Busby F1000Research 5, 2017 | 25 | 2017 |
Temporal resolution of gene derepression and proteome changes upon PROTAC-mediated degradation of BCL11A protein in erythroid cells S Mehta*, A Buyanbat*, Y Kai*, O Karayel, SR Goldman, D Seruggia, ... Cell Chemical Biology, 2022 | 23 | 2022 |
BAP1 is a haploinsufficient tumor suppressor linking chronic pancreatitis to pancreatic cancer in mice S Perkail, J Andricovich, Y Kai, A Tzatsos Nature Communications 11 (1), 3018, 2020 | 21 | 2020 |
Lysine-specific histone demethylases in normal and malignant hematopoiesis J Andricovich, Y Kai, A Tzatsos Experimental hematology 44 (9), 778-782, 2016 | 18 | 2016 |
A distinct core regulatory module enforces oncogene expression in KMT2A-rearranged leukemia T Harada, Y Heshmati, J Kalfon, MW Perez, JX Ferrucio, J Ewers, ... Genes & Development 36 (5-6), 368-389, 2022 | 16 | 2022 |
Secretome profiling identifies neuron-derived neurotrophic factor as a tumor-suppressive factor in lung cancer Y Zhang*, X Wu*, Y Kai*, CH Lee, F Cheng, Y Li, Y Zhuang, ... JCI insight 4 (24), 2019 | 10 | 2019 |
Matrin3 mediates differentiation through stabilizing chromatin loop-domain interactions and YY1 mediated enhancer-promoter interactions T Liu, Q Zhu, Y Kai, T Bingham, S Wang, HJ Cha, S Mehta, TM Schlaeger, ... Nature Communications 15 (1), 1274, 2024 | 4 | 2024 |
Lysine methyltransferase Kmt2d regulates naive CD8+ T cell activation-induced survival N Weng, J Kim, T Nguyen, J Cifello, R Ahmad, Y Zhang, Q Yang, JE Lee, ... Frontiers in Immunology 13, 8240, 2022 | 4* | 2022 |
Epigenetic regulation of lineage commitment in normal and malignant hematopoiesis by histone demethylase KDM2B J Andricovich, Y Kai, W Peng, A Foudi, A Tzatsos J. Clin. Invest 126, 905-920, 2016 | 2 | 2016 |