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Yan KAI
Yan KAI
Dana-Farber Cancer Institute, Harvard University
在 jimmy.harvard.edu 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
Loss of KDM6A Activates Super-Enhancers to Induce Gender-Specific Squamous-like Pancreatic Cancer and Confers Sensitivity to BET Inhibitors
J Andricovich, S Perkail, Y Kai, N Casasanta, W Peng, A Tzatsos
Cancer cell 33 (3), 512-526. e8, 2018
2672018
miR-137 mediates the functional link between c-Myc and EZH2 that regulates cisplatin resistance in ovarian cancer
J Sun, X Cai, MMH Yung, W Zhou, J Li, Y Zhang, Z Li, SS Liu, ...
Oncogene 38 (4), 564, 2019
1232019
Histone demethylase KDM2B regulates lineage commitment in normal and malignant hematopoiesis
AT Jaclyn Andricovich, Yan Kai, Weiqun Peng, Adlen Foudi
Journal of Clinical Investigation, 2016
922016
Transcription factor competition at the γ-globin promoters controls hemoglobin switching
N Liu, S Xu, Q Yao, Q Zhu, Y Kai, JY Hsu, P Sakon, L Pinello, GC Yuan, ...
Nature Genetics 53 (4), 511-520, 2021
742021
DUOXA1-mediated ROS production promotes cisplatin resistance by activating ATR-Chk1 pathway in ovarian cancer
Y Meng, CW Chen, MMH Yung, W Sun, J Sun, Z Li, J Li, Z Li, W Zhou, ...
Cancer Letters, 2018
662018
Predicting CTCF-mediated chromatin interactions by integrating genomic and epigenomic features
Y Kai, J Andricovich, Z Zeng, J Zhu, A Tzatsos, W Peng
Nature Communications 9 (1), 4221, 2018
552018
Highly stable and AC electric field-activated electrorheological fluid based on mesoporous silica-coated graphene nanosheets
J Yin, R Chang, Y Kai, X Zhao
Soft Matter 9 (15), 3910-3914, 2013
442013
Autocrine activation of JAK2 by IL-11 promotes platinum drug resistance
W Zhou, W Sun, MMH Yung, S Dai, Y Cai, CW Chen, Y Meng, JB Lee, ...
Oncogene, 1, 2018
352018
Inner nuclear protein Matrin-3 coordinates cell differentiation by stabilizing chromatin architecture
HJ Cha, Ö Uyan*, Y Kai*, T Liu, Q Zhu, Z Tothova, GA Botten, J Xu, ...
Nature Communications 12 (1), 1-19, 2021
322021
MLL:: AF9 degradation induces rapid changes in transcriptional elongation and subsequent loss of an active chromatin landscape
SN Olsen, L Godfrey, JP Healy, YA Choi, Y Kai, C Hatton, F Perner, ...
Molecular Cell 82 (6), 1140-1155. e11, 2022
292022
Mapping the evolving landscape of super-enhancers during cell differentiation
Y Kai, BE Li, M Zhu, GY Li, F Chen, Y Han, HJ Cha, SH Orkin, W Cai, ...
Genome Biology 22, 1-21, 2021
262021
dbVar structural variant cluster set for data analysis and variant comparison
L Phan, J Hsu, M Willi, T Mansour, Y Kai, J Garner, J Lopez, B Busby
F1000Research 5, 2017
252017
Temporal resolution of gene derepression and proteome changes upon PROTAC-mediated degradation of BCL11A protein in erythroid cells
S Mehta*, A Buyanbat*, Y Kai*, O Karayel, SR Goldman, D Seruggia, ...
Cell Chemical Biology, 2022
232022
BAP1 is a haploinsufficient tumor suppressor linking chronic pancreatitis to pancreatic cancer in mice
S Perkail, J Andricovich, Y Kai, A Tzatsos
Nature Communications 11 (1), 3018, 2020
212020
Lysine-specific histone demethylases in normal and malignant hematopoiesis
J Andricovich, Y Kai, A Tzatsos
Experimental hematology 44 (9), 778-782, 2016
182016
A distinct core regulatory module enforces oncogene expression in KMT2A-rearranged leukemia
T Harada, Y Heshmati, J Kalfon, MW Perez, JX Ferrucio, J Ewers, ...
Genes & Development 36 (5-6), 368-389, 2022
162022
Secretome profiling identifies neuron-derived neurotrophic factor as a tumor-suppressive factor in lung cancer
Y Zhang*, X Wu*, Y Kai*, CH Lee, F Cheng, Y Li, Y Zhuang, ...
JCI insight 4 (24), 2019
102019
Matrin3 mediates differentiation through stabilizing chromatin loop-domain interactions and YY1 mediated enhancer-promoter interactions
T Liu, Q Zhu, Y Kai, T Bingham, S Wang, HJ Cha, S Mehta, TM Schlaeger, ...
Nature Communications 15 (1), 1274, 2024
42024
Lysine methyltransferase Kmt2d regulates naive CD8+ T cell activation-induced survival
N Weng, J Kim, T Nguyen, J Cifello, R Ahmad, Y Zhang, Q Yang, JE Lee, ...
Frontiers in Immunology 13, 8240, 2022
4*2022
Epigenetic regulation of lineage commitment in normal and malignant hematopoiesis by histone demethylase KDM2B
J Andricovich, Y Kai, W Peng, A Foudi, A Tzatsos
J. Clin. Invest 126, 905-920, 2016
22016
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