NOTCH1 activation compensates BRCA1 deficiency and promotes triple-negative breast cancer formation K Miao, JH Lei, MV Valecha, A Zhang, J Xu, L Wang, X Lyu, S Chen, ... Nature communications 11 (1), 3256, 2020 | 80 | 2020 |
Molecular landscape and subtype-specific therapeutic response of nasopharyngeal carcinoma revealed by integrative pharmacogenomics RB Ding, P Chen, BK Rajendran, X Lyu, H Wang, J Bao, J Zeng, W Hao, ... Nature communications 12 (1), 3046, 2021 | 57 | 2021 |
Single-cell RNA-Seq reveals cell heterogeneity and hierarchy within mouse mammary epithelia H Sun, Z Miao, X Zhang, UI Chan, SM Su, S Guo, CKH Wong, X Xu, ... Journal of Biological Chemistry 293 (22), 8315-8329, 2018 | 50 | 2018 |
S100A9-CXCL12 activation in BRCA1-mutant breast cancer promotes an immunosuppressive microenvironment associated with resistance to immunotherapy J Li, X Shu, J Xu, SM Su, UI Chan, L Mo, J Liu, X Zhang, R Adhav, Q Chen, ... Nature communications 13 (1), 1481, 2022 | 42 | 2022 |
Characterization of BRCA1-deficient premalignant tissues and cancers identifies Plekha5 as a tumor metastasis suppressor J Liu, R Adhav, K Miao, SM Su, L Mo, UI Chan, X Zhang, J Xu, J Li, X Shu, ... Nature communications 11 (1), 4875, 2020 | 31 | 2020 |
BRCA1 represses DNA replication initiation through antagonizing estrogen signaling and maintains genome stability in parallel with WEE1–MCM2 signaling during pregnancy X Xu, E Chen, L Mo, L Zhang, F Shao, K Miao, J Liu, SM Su, M Valecha, ... Human molecular genetics 28 (5), 842-857, 2019 | 17 | 2019 |
Accelerating precision anti-cancer therapy by time-lapse and label-free 3D tumor slice culture platform F Xing, YC Liu, S Huang, X Lyu, SM Su, UI Chan, PC Wu, Y Yan, N Ai, J Li, ... Theranostics 11 (19), 9415, 2021 | 16 | 2021 |
Optimizing CRISPR/Cas9 technology for precise correction of the Fgfr3-G374R mutation in achondroplasia in mice K Miao, X Zhang, SM Su, J Zeng, Z Huang, UI Chan, X Xu, CX Deng Journal of Biological Chemistry 294 (4), 1142-1151, 2019 | 14 | 2019 |
ATP11B inhibits breast cancer metastasis in a mouse model by suppressing externalization of nonapoptotic phosphatidylserine J Xu, SM Su, X Zhang, UI Chan, R Adhav, X Shu, J Liu, J Li, L Mo, Y Wang, ... The Journal of Clinical Investigation 132 (5), 2022 | 11 | 2022 |
Dissecting the heterogeneity and tumorigenesis of BRCA1 deficient mammary tumors via single cell RNA sequencing H Sun, J Zeng, Z Miao, KC Lei, C Huang, L Hu, SM Su, UI Chan, K Miao, ... Theranostics 11 (20), 9967, 2021 | 5 | 2021 |
BRCA1 Insufficiency Induces a Hypersialylated Acidic Tumor Microenvironment That Promotes Metastasis and Immunotherapy Resistance X Shu, J Li, UI Chan, SM Su, C Shi, X Zhang, T An, J Xu, L Mo, J Liu, ... Cancer Research 83 (15), 2614-2633, 2023 | | 2023 |
In vivo Mouse Mammary Gland Formation H Sun, X Zhang, UI Chan, SM Su, S Guo, X Xu, C Deng Bio-protocol 10 (13), e3667-e3667, 2020 | | 2020 |