Iron-export ferroxidase activity of β-amyloid precursor protein is inhibited by zinc in Alzheimer's disease JA Duce, A Tsatsanis, MA Cater, SA James, E Robb, K Wikhe, SL Leong, ... Cell 142 (6), 857-867, 2010 | 838 | 2010 |
PBT2 rapidly improves cognition in Alzheimer's Disease: additional phase II analyses NG Faux, CW Ritchie, A Gunn, A Rembach, A Tsatsanis, J Bedo, ... Journal of Alzheimer's Disease 20 (2), 509-516, 2010 | 445 | 2010 |
ID1 and ID3 regulate the self-renewal capacity of human colon cancer-initiating cells through p21 CA O'Brien, A Kreso, P Ryan, KG Hermans, L Gibson, Y Wang, ... Cancer cell 21 (6), 777-792, 2012 | 257 | 2012 |
Zinc and copper modulate Alzheimer Aβ levels in human cerebrospinal fluid D Strozyk, LJ Launer, PA Adlard, RA Cherny, A Tsatsanis, I Volitakis, ... Neurobiology of aging 30 (7), 1069-1077, 2009 | 209 | 2009 |
β-Amyloid precursor protein does not possess ferroxidase activity but does stabilize the cell surface ferrous iron exporter ferroportin BX Wong, A Tsatsanis, LQ Lim, PA Adlard, AI Bush, JA Duce PloS one 9 (12), e114174, 2014 | 163 | 2014 |
SLC30A3 Responds to Glucose- and Zinc Variations in ß-Cells and Is Critical for Insulin Production and In Vivo Glucose-Metabolism During ß-Cell Stress K Smidt, N Jessen, AB Petersen, A Larsen, N Magnusson, JB Jeppesen, ... PLoS One 4 (5), e5684, 2009 | 114 | 2009 |
Amyloidogenic processing of Alzheimer’s disease β-amyloid precursor protein induces cellular iron retention A Tsatsanis, BX Wong, AP Gunn, S Ayton, AI Bush, D Devos, JA Duce Molecular psychiatry 25 (9), 1958-1966, 2020 | 70 | 2020 |
Amyloid precursor protein drives down-regulation of mitochondrial oxidative phosphorylation independent of amyloid beta MIG Lopez Sanchez, HS Waugh, A Tsatsanis, BX Wong, JG Crowston, ... Scientific reports 7 (1), 9835, 2017 | 46 | 2017 |
Protection from neurodegeneration in the 6-hydroxydopamine (6-OHDA) model of Parkinson's with novel 1-hydroxypyridin-2-one metal chelators DG Workman, A Tsatsanis, FW Lewis, JP Boyle, M Mousadoust, ... Metallomics 7 (5), 867-876, 2015 | 43 | 2015 |
The acute phase protein lactoferrin is a key feature of Alzheimer’s disease and predictor of Aβ burden through induction of APP amyloidogenic processing A Tsatsanis, AN McCorkindale, BX Wong, E Patrick, TM Ryan, RW Evans, ... Molecular psychiatry 26 (10), 5516-5531, 2021 | 41 | 2021 |
Post translational modulation of β-amyloid precursor protein trafficking to the cell surface alters neuronal iron homeostasis A Tsatsanis, S Dickens, JCF Kwok, BX Wong, JA Duce Neurochemical Research 44, 1367-1374, 2019 | 39 | 2019 |
Amine oxidase activity of β-amyloid precursor protein modulates systemic and local catecholamine levels JA Duce, S Ayton, AA Miller, A Tsatsanis, LQ Lam, L Leone, JE Corbin, ... Molecular psychiatry 18 (2), 245-254, 2013 | 21 | 2013 |
Changes in cortical protein markers of iron transport with gender, major depressive disorder and suicide B Dean, A Tsatsanis, LQ Lam, E Scarr, JA Duce The World Journal of Biological Psychiatry, 2020 | 19 | 2020 |
Synthesis, physicochemical characterization and neuroprotective evaluation of novel 1-hydroxypyrazin-2 (1 H)-one iron chelators in an in vitro cell model of Parkinson's disease FW Lewis, K Bird, JP Navarro, R El Fallah, J Brandel, V Hubscher-Bruder, ... Dalton Transactions 51 (9), 3590-3603, 2022 | 5 | 2022 |
Lactoferrin Interacts with the Amyloid-β Precursor Protein and Exacerbates Aβ Production A Tsatsanis University of Leeds, 2019 | | 2019 |
Innate immune response protein lactoferrin directly binds amyloid-beta precursor protein to promote amyloidogenic processing A Tsatsanis, T Ryan, B Wong, R Evans, A Bush, J Duce JOURNAL OF NEUROCHEMISTRY 142, 66-66, 2017 | | 2017 |
[P1–169]: LACTOFERRIN IS AN IRON TRANSPORTER AND KEY INNATE IMMUNE RESPONSE PROTEIN THAT DIRECTLY BINDS AMYLOID‐β PRECURSOR PROTEIN TO PROMOTE AMYLOIDOGENIC PROCESSING A Tsatsanis, TM Ryan, BX Wong, RW Evans, AI Bush, JA Duce Alzheimer's & Dementia 13 (7S_Part_6), P308-P308, 2017 | | 2017 |
[P3–153]: THE INFLUENCE OF AMYLOID‐B PRECURSOR PROTEIN PROTEOLYTIC PROCESSING ON NEURONAL IRON HOMEOSTASIS BX Wong, A Tsatsanis, LQ Lam, S Ayton, AP Gunn, D Devos, AI Bush, ... Alzheimer's & Dementia 13 (7S_Part_20), P993-P993, 2017 | | 2017 |
Evaluating Iron Flux in the Brain BX Wong, LQ Lam, A Tsatsanis, JA Duce Metals in the Brain: Measurement and Imaging, 161-193, 2017 | | 2017 |
The influence of amyloid-beta precursor protein proteolytic processing on neuronal iron homeostasis J Duce, B Wong, A Tsatsanis, L Lam, S Ayton, P Adlard, A Bush JOURNAL OF NEUROCHEMISTRY 134, 323-323, 2015 | | 2015 |