A pan-cancer blueprint of the heterogeneous tumor microenvironment revealed by single-cell profiling J Qian, S Olbrecht, B Boeckx, H Vos, D Laoui, E Etlioglu, E Wauters, ... Cell Research 30, 745-762, 2020 | 484 | 2020 |
Lineage-dependent gene expression programs influence the immune landscape of colorectal cancer HO Lee, Y Hong, HE Etlioglu, YB Cho, V Pomella, B Van den Bosch, ... Nature genetics 52 (6), 594-603, 2020 | 480 | 2020 |
A single-cell map of intratumoral changes during anti-PD1 treatment of patients with breast cancer A Bassez, H Vos, L Van Dyck, G Floris, I Arijs, C Desmedt, B Boeckx, ... Nature medicine 27 (5), 820-832, 2021 | 439 | 2021 |
An integrated gene expression landscape profiling approach to identify lung tumor endothelial cell heterogeneity and angiogenic candidates J Goveia, K Rohlenova, F Taverna, L Treps, LC Conradi, A Pircher, ... Cancer cell 37 (1), 21-36. e13, 2020 | 359 | 2020 |
Discriminating mild from critical COVID-19 by innate and adaptive immune single-cell profiling of bronchoalveolar lavages E Wauters, P Van Mol, AD Garg, S Jansen, Y Van Herck, L Vanderbeke, ... Cell research 31 (3), 272-290, 2021 | 290 | 2021 |
PP1/Repo-man dephosphorylates mitotic histone H3 at T3 and regulates chromosomal aurora B targeting J Qian, B Lesage, M Beullens, A Van Eynde, M Bollen Current Biology 21 (9), 766-773, 2011 | 226 | 2011 |
Monocyte-driven atypical cytokine storm and aberrant neutrophil activation as key mediators of COVID-19 disease severity L Vanderbeke, P Van Mol, Y Van Herck, F De Smet, S Humblet-Baron, ... Nature communications 12 (1), 4117, 2021 | 214 | 2021 |
Split‐BioID: a proximity biotinylation assay for dimerization‐dependent protein interactions S De Munter, J Görnemann, R Derua, B Lesage, J Qian, E Heroes, ... FEBS letters 591 (2), 415-424, 2017 | 114 | 2017 |
The importance of kinase–phosphatase integration: lessons from mitosis L Gelens, J Qian, M Bollen, AT Saurin Trends in cell biology 28 (1), 6-21, 2018 | 106 | 2018 |
Aurora B defines its own chromosomal targeting by opposing the recruitment of the phosphatase scaffold Repo-Man J Qian, M Beullens, B Lesage, M Bollen Current Biology 23 (12), 1136-1143, 2013 | 102 | 2013 |
High-grade serous tubo-ovarian cancer refined with single-cell RNA sequencing: specific cell subtypes influence survival and determine molecular subtype classification S Olbrecht, P Busschaert, J Qian, A Vanderstichele, L Loverix, T Van Gorp, ... Genome Medicine 13, 1-30, 2021 | 94 | 2021 |
Spindle checkpoint silencing: PP1 tips the balance B Lesage, J Qian, M Bollen Current Biology 21 (21), R898-R903, 2011 | 87 | 2011 |
Cdk1 orders mitotic events through coordination of a chromosome-associated phosphatase switch J Qian, M Beullens, J Huang, S De Munter, B Lesage, M Bollen Nature communications 6 (1), 10215, 2015 | 86 | 2015 |
Development of a peptide that selectively activates protein phosphatase‐1 in living cells J Chatterjee, M Beullens, R Sukackaite, J Qian, B Lesage, DJ Hart, ... Angewandte Chemie International Edition 51 (40), 10054-10059, 2012 | 78 | 2012 |
An attachment-independent biochemical timer of the spindle assembly checkpoint J Qian, MA García-Gimeno, M Beullens, MG Manzione, ... Molecular cell 68 (4), 715-730. e5, 2017 | 64 | 2017 |
Clinical practices underlie COVID-19 patient respiratory microbiome composition and its interactions with the host V Lloréns-Rico, AC Gregory, J Van Weyenbergh, S Jansen, T Van Buyten, ... Nature communications 12 (1), 6243, 2021 | 61 | 2021 |
IL1β promotes immune suppression in the tumor microenvironment independent of the inflammasome and gasdermin D M Kiss, L Vande Walle, PHV Saavedra, E Lebegge, H Van Damme, ... Cancer immunology research 9 (3), 309-323, 2021 | 57 | 2021 |
DNA methylation repels binding of hypoxia-inducible transcription factors to maintain tumor immunotolerance F D’anna, L Van Dyck, J Xiong, H Zhao, RV Berrens, J Qian, ... Genome biology 21, 1-36, 2020 | 55 | 2020 |
LINC00461 promotes cell migration and invasion in breast cancer through miR‐30a‐5p/integrin β3 axis L Dong, J Qian, F Chen, Y Fan, J Long Journal of cellular biochemistry 120 (4), 4851-4862, 2019 | 49 | 2019 |
4D-networking by mitotic phosphatases J Qian, C Winkler, M Bollen Current opinion in cell biology 25 (6), 697-703, 2013 | 35 | 2013 |